The pathogenesis of Cryptosporidiosis

Parasitology Today

Volumn 12, Issue 6, 1996, Pages 221-225

  Clark, Douglas P ^a   Sears, Cynthia L ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Division of Pediatric Infectious Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHILD; CRYPTOSPORIDIOSIS; CRYPTOSPORIDIUM PARVUM; DIARRHEA; HOST PARASITE INTERACTION; HUMAN; PARASITE VIRULENCE; REVIEW;

CRYPTOSPORIDIUM; CRYPTOSPORIDIUM PARVUM; CYNTHIA; PROTOZOA;

EID: 0030002674     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-4758(96)10018-1     Document Type: Review

References (41)

1. Garber, L.P. et al (1994) Potential risk factors for Cryptosporidium infection in dairy calves. J. Am. Vet. Med. Assoc. 205, 86-91
2. Newman, R.D. et al. (1994) Household epidemiology of Cryptosporidium parvum infection in an urban community in Northeast Brazil. Ann. Intern. Med. 120, 500-505
3. MacKenzie, W.R. et al. (1994) A massive outbreak in Milwaukee of Cryptosporidium infection transmitted through the public water supply. New Engl. J. Med. 331, 161-167
4. Current, W.L. and Garcia, L.S. (1991) Cryptosporidiosis. Clin. Microbiol. Rev. 4, 325-358
5. Zu, S-X. et al. (1992) Cryptosporidiosis: pathogenesis and immunology. Parasitology Today 8, 24-27
6. + absorption in enteric cryptosporidiosis of pigs. Gastroenterology 98, 1129-1140
7. Ussing, H.H. and Zerahn, K. (1951) Active transport of sodium as the source of electric current in the short-circuited isolated frog skin. Acta Physiol. Scand. 23, 110-127
8. Dharmsathaphorn, K. and Madara, J.L. (1990) Established intestinal cell lines as model systems for electrolyte transport studies. Methods Enzymol. 192, 354-389
9. Neutra, M. and Louvard, D. (1989) in Functional Epithelial Cells in Culture (Matlin, K.S. and Valentich, J.D., eds), pp 363-398, Alan R. Liss
10. Field, M., Rao, M.C. and Chang, E.B. (1989) Intestinal electrolyte transport and diarrheal disease (1st of two parts). New Engl. J. Med. 321, 800-806
11. Chang, E.B. and Rao, M.C. (1994) in Physiology of the Gastrointestinal Tract, 3rd edn (Johnson, L.R., ed.), pp 2027-2081, Raven Press
12. Ciancio, M.E. and Chang, E.B. (1992) Epithelial secretory response to inflammation. Ann. NY Acad. Sci. 664, 211-221
13. Powell, D.W. (1994) New paradigms for the pathophysiology of infectious diarrhea. Gastroenterology 106, 1705-1707
14. Sartor, R.B. (1994) Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology 106, 533-539
15. Field, M., Rao, M.C. and Chang, E.B. (1989) Intestinal electrolyte transport and diarrheal disease (2nd of two parts). New Engl. J. Med. 321, 879-883
16. Goodgame, R.W. et al. (1995) Intestinal function and injury in acquired immunodeficiency syndrome-related cryptosporidiosis. Gastroenterology 108, 1075-1082
17. Argenzio, R.A., Lecce, J. and Powell, D.W. (1993) Prostanoids inhibit intestinal NaCl absorption in experimental porcine cryptosporidiosis. Gastroenterology 104, 440-447
18. Giannella, R.A. (1979) Importance of the intestinal inflammatory reaction in Salmonella-mediated intestinal secretion. Infect. Immun. 23, 140-145
19. McGowan, K. et al. (1990) Role of prostaglandins and calcium in the effects of Entamoeba histolytica on colonic electrolyte transport. Gastroenterology 98, 873-880
20. Lawson, L.D. and Powell, D.W. (1987) Bradykinin-stimulated eicosanoid synthesis and secretion by rabbit ileal components. Am. J. Physiol. 252, G783-G790
21. Moore, R. et al. (1995) Temporal changes in permeability and structure of piglet ileum after site-specific infection by Cryptosporidium parvum. Gastroenterology 108, 1030-1039
22. + exchange in experimental porcine cryptosporidiosis. Gastroenterology 106, 1418-1428
23. Levine, S.A. et al. (1995) L-Glutamine in intestinal sodium absorption: lessons for physiology, pathobiology and therapy of diarrhea. Gastroenterology 106, 1698-1713
24. Schneeberger, E.E. and Lynch, R.D. (1992) Structure, function, and regulation of cellular tight junctions. Am. J. Physiol. 262, L647-L661
25. Adams, R.B. et al. (1994) Cryptosporidium parvum infection of intestinal epithelium: morphologic and functional studies in an in vitro model. J. Infect. Dis. 169, 170-177
26. Griffiths, J.K. et al. (1994) Cryptosporidium parvum infection of Caco-2 cell monolayers induces an apical monolayer defect, selectively increases trans-monolayer permeability, and causes epithelial cell death. Infect. Immun. 62, 4506-4514
27. Madara, J.L. and Trier, J.S. (1994) in Physiology of the Gastrointestinal Tract, 3rd edn (Johnson, L.R., ed.), pp 1577-1622, Raven Press
28. Guarino, A. et al. (1994) Enterotoxic effect of stool supernatant of Cryptosporidium-infected calves on human jejunum. Gastroenterology 106, 28-34
29. Sears, C.L. and Guerrant, R.L. (1994) Cryptosporidiosis: the complexity of intestinal pathophysiology. Gastroenterology 106, 252-267
30. Guarino, A. et al. (1995) Human intestinal cryptosporidiosis: secretory diarrhea and enterotoxic activity in Caco-2 cells. J. Infect. Dis. 171, 976-983
31. Klimpel, G.R. et al. (1995) Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract. Infect. Immun. 63, 1134-1137
32. Eckmann, L. et al. (1993) Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. Gastroenterology 105, 1689-1697
33. Kandil, H.M., Berschneider, H.M. and Argenzio, R.A. (1994) Tumour necrosis factor-α changes porcine intestinal ion transport through a paracrine mechanism involving prostaglandins. Gut 35, 934-940
34. Madara, J.L. and Stafford, J. (1989) Interferon-γ directly affects barrier function of cultured intestinal epithelial monolayers. J. Clin. Invest. 83, 724-772
35. Adams, R.B., Planchon, S.M. and Roche, J.K. (1993) IFN-γ modulation of epithelial barrier function. Timecourse, reversibility, and site of cytokine binding. J. Immunol. 150, 2356-2363
36. Chang, E.B., Musch, M.W. and Mayer, L. (1990) Interleukins 1 and 3 stimulate anion secretion in chicken intestine. Gastroenterology 98, 1518-1524
37. Chiossone, D.C., Simon, P.L. and Smith, P.L. (1990) Interleukin-1: effects on rabbit ileal mucosal ion transport in vitro. Eur. J. Pharmacol. 180, 217-228
38. Theodorou, V. et al. (1994) Interleukin-1 induces a neurally mediated colonie secretion in rats: involvement of mast cells and prostaglandins. Gastroenterology 106, 1493-1500
39. Flanigan, T. et al. (1992) Cryptosporidium infection and CD4 counts. Ann. Intern. Med. 116, 840-842
40. Powell, D.W. (1992) Epithelial secretory responses to inflammation. Platelet activating factor and reactive oxygen metabolites. Ann. NY Acad. Sci. 664, 232-247
41. Madara, J.L. et al. (1993) 5′-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers. J. Clin. Invest. 91, 2320-2325