Autocrine growth stimulation of SW403 colon carcinoma cell line is caused by transforming-growth-factor-α-mediated epidermal growth factor receptor activation

Journal of Cancer Research and Clinical Oncology

Volumn 122, Issue 6, 1996, Pages 328-334

  Hirsch, Thomas ^a   Eggstein, Stefan ^a   Frank, Sabine ^a   Farthmann, Eduard ^a   Specht, Bernd Ulrich V ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Autocrine stimulation; Colon carcinoma; EGF receptor; Monoclonal antibody; TGF

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; AUTOCRINE EFFECT; COLON CARCINOMA; CONTROLLED STUDY; GROWTH STIMULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL; CELL DIVISION; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR CELLS, CULTURED;

EID: 0030002610     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01220799     Document Type: Article

References (24)

1. Baldwin GS, Zhang QZ (1992) Measurement of gastrin and transforming growth factor a messenger RNA levels in colonie carcinoma cell lines by quantitative polymerase chain reaction. Cancer Res 52: 2261-2267
2. Brass LF, Ahuja M, Belmonte E, Blanchard N, Pizarro S, Tarver A, Hoxie JA (1994) Thrombin receptors: turning them off after turning them on. Semin Hematol 31: 251-260
3. Derynck R, Goeddel DV, Ulrich A, Gutterman JU, Williams RD, Bringman TS, Brger WH (1987) Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors. Cancer Res 47: 707-712
4. Fong CJ, Sherwood ER, Mendelsohn J, Lee C, Kozlowski JM (1992) Epidermal growth factor receptor monoclonal antibody inhibits constitutive receptor phosphorylation, reduces autonomous growth, and sensitizes androgen-independent prostatic carcinoma cells to tumor necrosis factor α. Cancer Res 52: 5887-5892
5. Frucht H, Gazdar AF, Park H, Jensen RT (1992) Characterization of functional receptors for gastrointestinal hormones on human colon cancer cells. Cancer Res 52: 1114-1122
6. Gopas J, Ono M, Pringler G, Smith MR, Tainsky MA, Siddiqui MAQ, Wishniak O, Segal S, Kuwano M, Kung HF (1992) EGF receptor activity and mitogenic response of BALB/3T3 cells expressing ras and myc oncogenes. Cell Mol Biol 38: 605-614
7. Gross ME, Zorbas MA, Danels YJ, Garcia R, Gallick GE, Olive M, Brattain MG, Boman BM, Yeoman LC (1991) Cellular growth response to epidermal growth factor in colon carcinoma cells with an amplified epidermal growth factor receptor derived from a familial adenomatous polyposis patient. Cancer Res 51: 1452-1459
8. Harris AL (1990) The epidermal growth factor receptor as a target for therapy. Cancer Cells 2: 321-323
9. Hofer D, Sherwood E, Bromberg W, Mendelsohn J, Lee C, Kozlowski J (1991) Autonomous growth of androgen-independent prostatic carcinoma cells: role of transforming growth factor α. Cancer Res 51: 2780-2785
10. Kaufmann WK, Zhang Y, Kaufmann DG (1992) Association between expression of transforming growth factor-alpha and progression of hepatocellular foci to neoplasms. Carcinogenesis 13: 1481-1483
11. Kohrer K, Domdey H (1990) Preparation of high molecular weight RNA. Methods Enzymol 194: 398-405
12. Kotsier PA, Schorr J, Dorfler W (1993) A rapid optimized protocol for downward alkaline Southern blotting of DNA. Biotechniques 15: 260-262
13. Leibovitz A, Stinson JC, McCombs WB, McCoy CE, Mazur KC, Mabry ND (1976) Classification of human colorectal adenocarcinoma cell lines. Cancer Res 36: 4562-4569
14. Markowitz SD, Molkentin K, Gerbic C, Jackson J, Stellato T, Willson JKV (1990) Growth stimulation by coexpression of transforming growth factor-α and epidermal growth factor-receptor in normal and adenomatous human colon epithelium. J Clin Invest 86: 356-362
15. Masui H, Moroyama T, Mendelsohn J (1986) Mechanism of antitumor activity in mice for antiepidermal growth factor receptor monoclonal antibodies with different isotypes. Cancer Res 46: 5592-5598
16. Ozanne B, Richards CS, Hendler F, Burns D, Gusterson B (1986) Overexpression of the EGF receptor is a hallmark of squamous cell carcinomas. J Pathol 149: 9-14
17. Santon JB, Cronin MT, MacLeod CL, Mendelsohn J, Masui H, Gill GN (1986) Effects of epidermal growth factor receptor concentration to tumorgenicity of A431 cells in nude mice. Cancer Res 46: 4701-4704
18. Sporn MB, Roberts AB. Autocrine growth factors and cancer (1988) Nature 313: 745-747
19. Stancovski I, Hurwitz E, Leitner O, Ullrich A, Yarden Y, Sela M (1991) Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB2 receptor on tumor growth. Proc Natl Acad Sci USA 88: 8691-8695
20. Utawale S, Zorbas MA, Hodgson CP, Coffey RJ, Gallick GE, North SM, Wildrick DM, Olive M, Blick M, Yeoman LC, Boman BM (1993) Transforming growth factor-α production and autoinduction in a colorectal carcinoma cell line (DiFi) with an amplified epidermal growth factor receptor gene. Cancer Res 53: 1630-1636
21. Velu TJ, Beguinot L, Vass WC, Willingham MC, Merlino GT, Pastan I, Lowy DR (1987) Epidermal growth factor dependent transformation by a human EGF receptor proto-oncogene. Science 238: 1408-1410
22. Winkel Madsen M, Lykkesfeldt AE, Laursen I, Vang Nielsen K, Briand P (1992) Altered gene expression of c-myc, epidermal growth factor receptor, transforming growth factor-α, and c-erb-B2 in an immortalized human breast epithelial cell line, HMT-3522, is associated with decreased growth factor requirements. Cancer Res 52: 1210-1217
23. Weiner TM, Liu ET, Craven RJ, Cance WG (1994) Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors. Ann Surg Oncol 1: 18-27
24. Zyzyk LL, MacDonald LM, Batova A, Forand R, Creek KE, Pirisi L (1994) Increased levels and constitutive tyrosine phosphorylation of the epidermal growth factor receptor contribute to autonomous growth of human papillomavirus type 16 immortalized human keratinocytes. Cell Growth Differ 5: 537-547