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Interleukln-3, granulocyte-macrophage colony stimulating factor, and interleukin-5 transduce signals through two forms of STAT5
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Mui AL, Wakao H, Harada N, O'Farell A, Miyajima A: Interleukln-3, granu • locyte-macrophage colony stimulating factor, and interleukin-5 transduce signals through two forms of STAT5. J Leukoc Biol 1995, 57:799-803. Demonstrate that GM-CSF receptor activation is associated with enhanced phosphorylation of Jak2 and movement of STAT5 proteins to the cell nucleus.
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(1995)
J Leukoc Biol
, vol.57
, pp. 799-803
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Mui, A.L.1
Wakao, H.2
Harada, N.3
O'Farell, A.4
Miyajima, A.5
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43
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0029010473
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Thrombopoietln activates a STAT5-like factor in hematopoietic cells
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Pallard C, Gouilleux F, Benit L, Cocault L, Souyri M, Levy D, Groner B, • Gisselbrecht S, Dusanter-Fourt I: Thrombopoietln activates a STAT5-like factor in hematopoietic cells. EMBO J 1995, 14:2847-2856. Identifies novel STAT5-like factor in hematopoietic cells. Demonstrates activation of STAT5 by several factors, including SLF (SCF) and GM-CSF.
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(1995)
EMBO J
, vol.14
, pp. 2847-2856
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Pallard, C.1
Gouilleux, F.2
Benit, L.3
Cocault, L.4
Souyri, M.5
Levy, D.6
Groner, B.7
Gisselbrecht, S.8
Dusanter-Fourt, I.9
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44
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0029117304
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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
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Wen Z, Zhong Z, Damell JE: Maximal activation of transcription by •• Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995, 82:241-250. Key paper demonstrating that serine phosphorylation is required for activation of some STAT proteins. Provides evidence linking Jak/STAT pathways with serine/threonine kinases, such as MAP kinase.
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(1995)
Cell
, vol.82
, pp. 241-250
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Wen, Z.1
Zhong, Z.2
Damell, J.E.3
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45
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0029133702
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Requirement for MAP kinase (ERK2) activity in Interferon α- and interferon β-stimulated gene expression through STAT protein
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David M, Petricoin E, Benjamin C, Pine R, Weber MJ, Larner AC: •• Requirement for MAP kinase (ERK2) activity in Interferon α- and interferon β-stimulated gene expression through STAT protein. Science 1995, 269:1721-1723. Shows a clear link between the action of MAP kinase and activation of STAT proteins involved in gene transcription. Provides evidence that links two major signaling pathways together.
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(1995)
Science
, vol.269
, pp. 1721-1723
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David, M.1
Petricoin, E.2
Benjamin, C.3
Pine, R.4
Weber, M.J.5
Larner, A.C.6
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46
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4243852462
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Hyper-phosphorylation of STAT3 by steel factor in human factor-dependent myeloid cell lines
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Gotoh A, Takahira H, Mantel C, Broxmeyer HE: Hyper-phosphorylation of STAT3 by steel factor in human factor-dependent myeloid cell lines [abstract]. Blood 1995, 86(suppl 1):152a.
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(1995)
Blood
, vol.86
, Issue.1 SUPPL.
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Gotoh, A.1
Takahira, H.2
Mantel, C.3
Broxmeyer, H.E.4
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47
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0028847937
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The combination of Steel factor and GM-CSF blocks apoptosls induced by retinoic acid and upregulates AP-1 in a human growth factor-dependent cell line
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Horie M, Broxmeyer HE: The combination of Steel factor and GM-CSF blocks apoptosls induced by retinoic acid and upregulates AP-1 In a human growth factor-dependent cell line. Exp Hematol 1995, 23:168-173.
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(1995)
Exp Hematol
, vol.23
, pp. 168-173
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Horie, M.1
Broxmeyer, H.E.2
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48
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0027300330
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Comparative analysis of the suppressive effects of the human macrophage Inflammatory protein family of cytokines (chemoklnes) on proliferation of human myeloid progenitor cells
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Broxmeyer HE, Sherry B, Cooper S, Lu L, Maze R, Beckmann MP, Cerami A, Ralph P: Comparative analysis of the suppressive effects of the human macrophage Inflammatory protein family of cytokines (chemoklnes) on proliferation of human myeloid progenitor cells. J Immunol 1993, 150:3448-3458.
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(1993)
J Immunol
, vol.150
, pp. 3448-3458
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Broxmeyer, H.E.1
Sherry, B.2
Cooper, S.3
Lu, L.4
Maze, R.5
Beckmann, M.P.6
Cerami, A.7
Ralph, P.8
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49
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0029122028
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Synerglstic induction of phospholipid metabolism by granulocyte-macrophage colony stimulating factor and steel factor in a human growth factor-dependent cell line, MO7e
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Mantel C, Luo Z, Broxmeyer HE: Synerglstic induction of phospholipid metabolism by granulocyte-macrophage colony stimulating factor and steel factor In a human growth factor-dependent cell line, MO7e. Lipids 1995, 30:641-647. Demonstrates that signaling by lipid molecules may play a role in mediating the synergistic growth-promoting effects of GM-CSF and SLF on hematopoietic cells.
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(1995)
Lipids
, vol.30
, pp. 641-647
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Mantel, C.1
Luo, Z.2
Broxmeyer, H.E.3
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