Use of real-time confocal laser scanning microscopy to study immediate effects of photodynamic activation on photosensitized erythrocytes

Cancer Letters

Volumn 101, Issue 2, 1996, Pages 165-169

  Rollan, A ^a   Ward, T ^a   Flynn, G ^b   McKerr, G ^a   McHale, L ^a   McHale, A P ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b Quadrant   (United Kingdom)

Author keywords

Chemotherapy; Confocal scanning microscopy; Photodynamic therapy; Photosensitized erythrocytes

Indexed keywords

HEMATOPORPHYRIN DERIVATIVE; PHOTOSENSITIZING AGENT;

ARTICLE; CELL DAMAGE; DRUG DELIVERY SYSTEM; ERYTHROCYTE; HUMAN; HUMAN CELL; IRRADIATION; LASER MICROSCOPY; METHODOLOGY; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL;

EID: 0030002071     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04150-X     Document Type: Article

References (10)

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5. Flynn, G., McHale, L. and McHale, A.P. (1994) Methotrexate-loaded, photosensitized erythrocytes: a photo-activatable carrier/delivery system for use in cancer therapy. Cancer Lett., 82, 225-229.
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7. Dougherty, T.J. (1985) Photodynamic therapy. In: Methods in Porphyrin Photosensitization, pp. 313-323. Editor: D. Kessel. Plenum Press, New York.
8. Flynn, G., Hackett, T.J., McHale, L. and McHale, A.P. (1994) Encapsulation of the thrombolytic enzyme, brinase, in photosensitized erythrocytes: a novel thrombolytic system based on photodynamic activation. J. Photochem. Photobiol. B - Biol., 26, 193-196.
9. Kramer, B., Humber, A. and Hermann, A. (1993) Photodynamic effect on the nuclear envelope of human skin fibroblasts. J. Photochem. Photobiol., B - Biol., 17, 109-114.
10. Bachor, R., Scholz, M., Shea, C.R., and Hasan, T. (1991) Mechanism of photosensitization by microsphere bound chlorin-E6 in human bladder carcinoma cells. Cancer Res., 51, 4410-4414.