Molecular characterization, genomic arrangement, and expression of bmpD, a new member of the bmp class of genes encoding membrane proteins of Borrelia burgdorferi

Infection and Immunity

Volumn 64, Issue 4, 1996, Pages 1259-1264

  Ramamoorthy, Ramesh ^a   Povinelli, Laura ^a   Philipp, Mario T ^a,b  

^a TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^b TRPRC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; COMPLEMENT; DNA; GENE PRODUCT; MEMBRANE PROTEIN; RNA; SIGNAL PEPTIDASE;

ANIMAL MODEL; ARTICLE; BORRELIA BURGDORFERI; BORRELIA INFECTION; CHROMOSOME; CONTROLLED STUDY; DNA SEQUENCE; GENE; GENE CLUSTER; GENE EXPRESSION; IMMUNOBLOTTING; MONKEY; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING; TREPONEMA PALLIDUM;

EID: 0030002056     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.4.1259-1264.1996     Document Type: Article

References (29)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool J. Mol. Biol. 215:403-410.
2. Aron, L., M. Alekshun, L. Perlee, I. Schwartz, H. P. Godfrey, and F. C. Cabello. 1994. Cloning and DNA sequence analysis bmpC, a gene encoding a potential membrane lipoprotein of Barrelia burgdorferi FEMS Lett 123:75-82
3. Aydintug, M., Y. Gu, and M. T. Philipp. 1994. Borrelia burgdorferi antigens that are targeted by antibody-dependent complement-mediated killing in the rhesus monkey. Infect Immun. 62:4929-4937.
4. Barbour, A. G., R. A. Heiland, and T. R. Rowe. 1985. Heterogeneity of the major proteins in Lyme disease borreliac. a molecular analysis of North American and European isolates J. Infect. Dis. 152:478-484.
5. Braun, V., and H. C. Wu. 1994. Lipoproteins, structure, function, biosynthesis and model for protein export, p 319-341. In J. M. Ghuysen and R Hakembeck (ed.), Bacterial cell wall Elsevier Science, New York.
6. Gabain, A., J. G. Belasco, J. L. Schottel, C. Y. Chang, and S. N. Cohen. 1983. Decay of mRNA in Escherichia coli: investigation of the fate of specific segments of transcripts. Proc. Natl Acad. Sci USA 80:653-657.
7. Gazumyan, A., J. J. Schwartz, D. Liveris, and I. Schwartz. 1994. Sequence analysis of the ribosomal RNA operon of the Lyme disease spirochete. Borrelia burgdorferi. Gene 146:57-65.
8. Herrin, D. L., and G. W. Schmidt. 1988 Rapid reversible staining of Northern blots prior to hybridization. BioTechniques 6:196-200.
9. Jauris-Heipke, S., R. Fuchs, M. Motz, V. Preac-Mursic, E. Schwab, E. Soutschek, G. Will, and B. Wilske. 1993. Genetic heterogeneity of the genes coding for the outer surface protein C (OspC) and the flagellin of Borrelia burgdorferi. Med. Microbiol. Immunol. 182:37-50
10. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685
11. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
12. Marconi, R. T., and C. F. Garon. 1992. Development of a polymerase chain reaction primer sets for diagnosis of Lyme disease and for species-specific identification of Lyme disease isolates by 16S rRNA signature nucleotide analysis. J. Clin. Microbiol. 30:2830-2834.
13. Marconi, R. T., M. E. Konkel, and G. F. Garon. 1993. Variability of osp genes and gene products among species of Lyme disease spirochetes. Infect Immun. 61:2611-2617.
14. Philipp, M. T., M. K. Aydintug, R. P. Bohm, Jr., F. B. Cogswell, V. A. Dennis, H. N. Lanners, R. C. Lowrie, Jr., E. D. Roberts, M. D. Conway, M. Karacorlu, G. A. Peyman, D. J. Gubler, B. J. B. Johnson, J. Piesman, and Y. Gu. 1993. Early and early-disseminated phases of Lyme disease in the rhesus monkey: a model for infection in humans. Infect Immun. 61:3047-3059.
15. Philipp, M. T., and B. J. B. Johnson. 1994. Animal models of Lyme disease: pathogenesis and immunoprophylaxis. Trends Microbiol. 2:431-437.
16. Piesman, J., T. N. Mather, R. Sinsky, and A. Spielman. 1987 Duration of tick attachment and Borrelia burgdorferi transmission. J Clin Microbiol 25:557-558
17. Pollack, R. J., S. R. Telford III, and A. Spielman. 1993 Standardization of medium for culturing Lyme disease spirochetes. J. Clin. Microbiol. 31:1251-1255.
18. Roberts, E. D., R. Bohm, Jr., F. B. Cogswell, H. N. Lanners, R. C. Lowrie, Jr., L. Povinelli, J. Piesman, and M. T. Philipp. 1995. Chronic Lyme disease in the rhesus monkey. Lab. Invest. 72:146-160.
19. Rosa, P. Personal communication.
20. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc Natl. Acad Sci. USA 74:5463-5467
21. Simpson, W. J., W. Cieplak, M. E. Schrumpf, A. G. Barbour, and T. G. Schwan. 1994. Nucleotide sequence analysis of the gene in Borrelia burgdorferi encoding the immunogenic P39 antigen. FEMS Lett. 119:381-388
22. Simpson, W. J., M. E. Schrumpf, and T. G. Schwan. 1990. Reactivity of human Lyme borreliosis sera with a 39-kilodalton antigen specific to Borrelia burgdorferi J. Clin. Microbiol. 28:1329-1337.
23. Smith, D. E., and P. A. Fisher. 1984. Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots. J Clin Microbiol. 32:423-429.
24. Swancutt, M. A., J. D. Radolf, and M. V. Norgard. 1990. The 34-kilodalton membrane immunogen of Treponema pallidum is a lipoprotein. Infect Immun. 58:384-392.
25. Swancutt, M. A., B. S. Riley, J. D. Radolf, and M. V. Norgard. 1989. Molecular characterization of the pathogen-specific, 34-kilodalton membrane immunogen of Treponema pallidum. Infect Immun. 57:3314-3323.
26. Theisen, M., M. Borre, M. J. Mathiesen, B. Mikkelsen, A. Lebech, and K. Hansen. 1995. Evolution of the Borrelia burgdorferi outer surface protein OspC. J. Bacteriol. 177:3036-3044
27. Theisen, M., B. Frederiksen, A.-M. Lebech, J. Vuust, and K. Hansen. 1993. Polymorphism in the ospC gene of Borrelia burgdorferi and immunoreactivity of OspC protein, implications for taxonomy and for use of OspC protein as a diagnostic antigen. J Clin Microbiol. 31:2570-2576.
28. von Heijne, G. 1985. Signal sequences: the limits of variation. J. Mol. Biol. 184:99-105.
29. Wilske, B., V. Preac-Mursic, S. Jauris, A. Hofmann, I. Pradel, E. Soutschek, E. Schwab, G. Will, and G. Wanner. 1993. Immunological and molecular polymorphisms of OspC, an immunodominant major outer surface protein of Borrelia burgdorferi. Infect. Immun 61:2182-2191