Neurofilament phosphorylation is modulated by myelination

Journal of Neuroscience Research

Volumn 44, Issue 4, 1996, Pages 328-337

  Starr, R ^a,b   Attema, B ^c   DeVries, G H ^c   Monteiro, M J ^a,b  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

glia; kinases; neurons

Indexed keywords

PHOSPHOTRANSFERASE;

ACTIN FILAMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; ENZYME ACTIVITY; GLIA CELL; IMMUNOREACTIVITY; INTERMEDIATE FILAMENT; MYELINATION; NERVE GROWTH; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SCIATIC NERVE; SPINAL GANGLION;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; AXONS; CELLS, CULTURED; COCULTURE TECHNIQUES; EPITOPES; GANGLIA, SPINAL; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MYELIN SHEATH; NEUROFILAMENT PROTEINS; NEURONS; PHOSPHORYLATION; PROTEIN KINASES; RATS; RECOMBINANT PROTEINS; SCHWANN CELLS; SCIATIC NERVE;

EID: 0030001999     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19960515)44:4<328::AID-JNR3>3.0.CO;2-E     Document Type: Article

References (38)

1. Bolin LM, Shooter EM (1993): Neurons regulate Schwann cell genes by diffusible molecules. J Cell Biol 123:237-243.
2. Brockes JP, Fields KL, Raff MC (1979): Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve. Brain Res 227:105-118.
3. Carden MJ, Trojanowski JQ, Schlaepfer WW, Lee VM-Y (1987): Two stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns. J Neurosci 7:3489-3504.
4. Cole JS, Messing A, Trojanowski JQ, Lee VM-Y (1994): Modulation of axon diameter and neurofilaments by hypomyelinating Schwann cells in transgenic mice. J Neurosci 14:6956-6966.
5. de Waegh SM, Brady ST (1991): Local control of axonal properties by Schwann cells: neurofilaments and axonal transport in homologous and heterologous nerve grafts. J Neurosci Res 30:201-212.
6. de Waegh SM, Lee VM-Y. Brady ST (1992): Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell 68:451-463.
7. Eldridge E, Bunge MB, Bunge RP, Wood PM (1987): Differentiation of axon-related Schwann cells in vitro. 1. Ascorbic acid regulated basal lamina assembly and myelin formation. J Cell Biol 105:1023-1034.
8. Eyer J, Peterson A (1994): Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein. Neuron 12:389-405.
9. Friede RL, Samorajski T (1970): Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice. Anat Rec 167:379-388.
10. Geahlean RL, Anostario M, Low PS, Harrison ML (1986): Detection of protein kinase activity in sodium dodecyl sulphate-polyacrylamide gels. Anal Biochem 153:151-158.
11. Gotow T, Tanaka J (1994) Phosphorylation of neurofilament H sub-unit as related to arrangement of neurofilaments. J Neurosci Res 37:691-713.
12. Harris J, Ayyub C, Shaw G (1991): A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. J Neurosci Res 30:47-62.
13. Henry EW, Cowen JS, Sidman RL (1983): Comparison of Trembler and Trembler-J mouse phenotypes: varying severity of peripheral hypomyelination. J Neuropathol Exp Neurol 42:688-706.
14. Hisagana S-H, Hirokawa N (1988): Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing. J Mol Biol 202:297-305.
15. Hoffman PN, Lasek RJ (1975): The slow component of axonal transport: identification of the major structural polypeptides of the axon and their generality among mammalian neurons. J Cell Biol 66:351-366.
16. Hoffman P, Cleveland D, Griffin J, Landes P, Cowan N, Price D (1987): Neurofilament gene expression: a major determinant of axonal caliber. Proc Natl Acad Sci USA 84:3472-3476.
17. Hsieh S-T, Kidd GJ, Crawford TO, Xu Z, Lin W-M, Trapp BD, Cleveland DW, Griffin JW (1994): Regional modulation of neurofilament organization by myelination in normal axons. J Neurosci 14:6392-6401.
18. Inuzuka T, Quarles RH, Heath J, Trapp BD (1985): Myelin-associated glycoprotein and other proteins in Trembler mice. J Neurochem 44:793-797.
19. Lee VM-Y, Garden MJ, Schlaepfer WW, Trojanowski JQ (1987): Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats. J Neurosci 7:3474-3488.
20. Lee VM-Y, Otvos L, Garden MJ, Hollosi M, Dietzschold B, Lazzarini RA (1988): Identification of the major multiphosphorylation site in mammalian neurofilaments. Proc Natl Acad Sci USA 85:1998-2002.
21. Mata M, Kupina N, Fink DJ (1992): Phosphorylation-dependent epitopes are reduced at the node of Ranvier. J Neurocytol 21: 199-210.
22. Moya F, Bunge MB, Bunge RP (1980): Schwann cells proliferate but fail to differentiate in defined media. Proc Natl Acad Sci USA 77:6902-6906.
23. Neuberger TJ, DeVries GH (1993): Distribution of fibroblast growth factor in cultured dorsal root ganglion neurons and Schwann cells. I. Localization during maturation in vitro. J Neurocytol 22:436-448.
24. Nixon RA (1993): The regulation of neurofilament protein dynamics by phosphorylation: clues to neurofibrillary pathobiology. Brain Pathol 3:29-38.
25. Nixon RA, Sihag RK (1991): Neurofilament phosphorylation: a new look at regulation and function. TINS 14:501-505.
26. Nixon RA, Paskevich PA, Sihag RK, Thayer CY (1994): Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber. J Cell Biol 126:1031-1046.
27. Roder HM, Ingram VM (1991): Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios. J Neurosci 11:3325-3343.
28. Sakaguchi T, Okada M, Kitamura T, Kawasaki K (1993): Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail. Neurosci Lett 153:65-68.
29. Sharp GA, Shaw G, Weber K (1982): Immunoelectronmicroscopal localization of the three neurofilament proteins along neurofilaments in cultured dorsal root ganglion cell. Exp Cell Res 137:403-413.
30. Starr R, Xiao J, Monteiro MJ (1995): Production of monoclonal antibodies against neurofilament-associated proteins: demonstration of association with NF by a co-immunoprecipitation method. J Neurochem 64:1860-1867.
31. Sternberger L, Sternberger N (1983): Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc Natl Acad Sci USA 80:6126-6130.
32. Suter U, Welcher AW, Snips GJ (1993): Progress in the molecular understanding of hereditary peripheral neuropathies reveals new insights into the biology of the peripheral nervous system. TINS 16:50-56.
33. Umemori H, Sato S, Yagi T, Aizawa S, Yamamoto T (1994): Initial events of myelination involve FYN tyrosine kinase signalling. Nature 367:572-576.
34. Willard MB, Simon C (1981): Antibody decoration of neurofilaments. J Cell Biol 89:189-205.
35. Windebank AJ, Wood P, Bunge RP, Dyke PJ (1985): Myelination determines the caliber of dorsal root ganglion neurons in culture. J Neurosci 5:1563-1569.
36. Xiao J, Monteiro MJ (1994): Identification and characterization of a novel (115 kDa) neurofilament-associated kinase. J Neurosci 14:1820-1833.
37. Yamasaki H, Itakura C, Mizutani M (1991): Hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the Japanese quail. Acta Neuropathol (Berl) 82:427-434.
38. Yamasaki H, Bennett GS, Itakura C, Mizutani M (1992): Defective expression of neurofilament protein subunits in hereditary hypotrophic axonopathy of quail. Lab Invest 66:734-743.