Physiologic pharmacokinetic modeling of gastrointestinal blood flow as a rate-limiting step in the oral absorption of digoxin: Implications for patients with congestive heart failure receiving epoprostenol

Journal of Pharmaceutical Sciences

Volumn 85, Issue 5, 1996, Pages 473-477

  Carlton, Lisa D ^a,b   Pollack, Gary M ^a   Brouwer, Kim L R ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; PROSTACYCLIN DERIVATIVE;

ARTICLE; CONGESTIVE HEART FAILURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; GLOMERULUS FILTRATION RATE; INTESTINE BLOOD FLOW; KIDNEY BLOOD FLOW; LIVER BLOOD FLOW; MESENTERY BLOOD FLOW;

ADULT; BIOLOGICAL AVAILABILITY; DIGOXIN; EPOPROSTENOL; EVALUATION STUDIES; HEART FAILURE, CONGESTIVE; HUMANS; INTESTINAL ABSORPTION; MATHEMATICAL COMPUTING; MODELS, BIOLOGICAL; REGIONAL BLOOD FLOW; REPRODUCIBILITY OF RESULTS;

EID: 0030001630     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9503993     Document Type: Article

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