메뉴 건너뛰기




Volumn 132, Issue 1-2, 1996, Pages 189-194

Nasal administration of glucagon combined with dimethyl-β-cyclodextrin: Comparison of pharmacokinetics and pharmacodynamics of spray and powder formulations

Author keywords

Absorption enhancers; Bioavailability; Dimethyl cyclodextrin; Glucagon; Nasal absorption; Pharmacodynamics; Pharmacokinetics

Indexed keywords

BETA CYCLODEXTRIN DERIVATIVE; DIMETHYL BETA CYCLODEXTRIN; GLUCAGON; UNCLASSIFIED DRUG;

EID: 0030001516     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04385-3     Document Type: Article
Times cited : (26)

References (13)
  • 1
    • 0018097703 scopus 로고
    • Effect of bile salts on human erythrocytes: Plasma membrane vesiculation, phospholipid solubilization and their possible relationships to bile secretion
    • Billington, D. and Coleman, R., Effect of bile salts on human erythrocytes: Plasma membrane vesiculation, phospholipid solubilization and their possible relationships to bile secretion. Biophys. Acta, 509 (1978) 33-47.
    • (1978) Biophys. Acta , vol.509 , pp. 33-47
    • Billington, D.1    Coleman, R.2
  • 2
    • 0005772201 scopus 로고
    • Glucagon treatment of insulin reactions
    • Elrick, H., Witten, T.A. and Yoshiki, A., Glucagon treatment of insulin reactions. N. Engl. J. Med., 258 (1958) 476-480.
    • (1958) N. Engl. J. Med. , vol.258 , pp. 476-480
    • Elrick, H.1    Witten, T.A.2    Yoshiki, A.3
  • 3
    • 0023884625 scopus 로고
    • Effect of intranasal glucagon on blood glucose levels in healthy subjects and hypoglycemic patients with insulin-dependent diabetes
    • Freychet, L., Rizkalla, S.W., Desplanque, N., Basdevant, A., Zirinis, P., Tchobroutsky, G. and Slama, G., Effect of intranasal glucagon on blood glucose levels in healthy subjects and hypoglycemic patients with insulin-dependent diabetes. Lancet, 1 (1988) 1364-1366.
    • (1988) Lancet , vol.1 , pp. 1364-1366
    • Freychet, L.1    Rizkalla, S.W.2    Desplanque, N.3    Basdevant, A.4    Zirinis, P.5    Tchobroutsky, G.6    Slama, G.7
  • 4
    • 0020695631 scopus 로고
    • Hypoglycemic reactions in 172 type 1 (insulin-dependent) diabetic patients
    • Goldgewicht, C., Slama, G. and Tchobroutsky, G., Hypoglycemic reactions in 172 Type 1 (insulin-dependent) diabetic patients. Diabetologia, 24 (1983) 95-99.
    • (1983) Diabetologia , vol.24 , pp. 95-99
    • Goldgewicht, C.1    Slama, G.2    Tchobroutsky, G.3
  • 6
    • 85029996422 scopus 로고    scopus 로고
    • European Patent 883302118.1, November 1, 1983
    • Hirai, S., Okada, H., Yashiki, T. and Uda, Y., European Patent 883302118.1, November 1, 1983.
    • Hirai, S.1    Okada, H.2    Yashiki, T.3    Uda, Y.4
  • 7
    • 0026760187 scopus 로고
    • Enhancing effects of cyclodextrins on nasal absorption of insulin in rats
    • Irie, T., Wakamatsu, K., Arima, H., Aritomi, H. and Uekama, K., Enhancing effects of cyclodextrins on nasal absorption of insulin in rats. Int. J. Pharm., 84 (1992) 129-139.
    • (1992) Int. J. Pharm. , vol.84 , pp. 129-139
    • Irie, T.1    Wakamatsu, K.2    Arima, H.3    Aritomi, H.4    Uekama, K.5
  • 8
    • 0025878065 scopus 로고
    • Absorption enhancing effect of cyclodextrins on intranasally administered insulin in rats
    • Merkus, F.W.H.M., Verhoef, J.C., Romeijn, S.G. and Schipper, N.G.M., Absorption enhancing effect of cyclodextrins on intranasally administered insulin in rats. Pharm. Res., 8 (1991) 588-592.
    • (1991) Pharm. Res. , vol.8 , pp. 588-592
    • Merkus, F.W.H.M.1    Verhoef, J.C.2    Romeijn, S.G.3    Schipper, N.G.M.4
  • 9
    • 0024806367 scopus 로고
    • Differential effects of α-, β-and γ-cyclodextrins on human erythrocytes
    • Ohtani, Y., Irie, T., Uekama, K., Fukunaga, K. and Pitha, J., Differential effects of α-, β-and γ-cyclodextrins on human erythrocytes. Eur. J. Biochem., 186 (1989) 17-22.
    • (1989) Eur. J. Biochem. , vol.186 , pp. 17-22
    • Ohtani, Y.1    Irie, T.2    Uekama, K.3    Fukunaga, K.4    Pitha, J.5
  • 10
    • 0024450507 scopus 로고
    • Nasal administration of glucagon and human calcitonin to healthy subjects: A comparison of powders and spray solutions and of different enhancing agents
    • Pontiroli, A.E., Alberetto, M., Calderara, A., Pajetta, E. and Pozza, G., Nasal administration of glucagon and human calcitonin to healthy subjects: a comparison of powders and spray solutions and of different enhancing agents. Eur. J. Clin. Pharmacol., (1989) 427-430.
    • (1989) Eur. J. Clin. Pharmacol., , pp. 427-430
    • Pontiroli, A.E.1    Alberetto, M.2    Calderara, A.3    Pajetta, E.4    Pozza, G.5
  • 11
    • 0021997465 scopus 로고
    • Metabolic effects of intranasaly administered glucagon: Comparison with intramuscular and intravenous injections
    • Pontiroli, A.E., Alberetto, M. and Pozza, G., Metabolic effects of intranasaly administered glucagon: comparison with intramuscular and intravenous injections. Acta Diab. Lat., 22 (1985) 103-109.
    • (1985) Acta Diab. Lat. , vol.22 , pp. 103-109
    • Pontiroli, A.E.1    Alberetto, M.2    Pozza, G.3
  • 12
    • 0026663934 scopus 로고
    • Absorption enhancers in nasal insulin delivery and their influence on nasal ciliary functioning
    • Schipper, N.G.M., Verhoef, J., Romeijn, S.G. and Merkus, F.W.H.M., Absorption enhancers in nasal insulin delivery and their influence on nasal ciliary functioning. J. Controlled Release, 21 (1992) 173-186.
    • (1992) J. Controlled Release , vol.21 , pp. 173-186
    • Schipper, N.G.M.1    Verhoef, J.2    Romeijn, S.G.3    Merkus, F.W.H.M.4
  • 13
    • 0025084084 scopus 로고
    • A new non-invasive method for treating insulin reaction: Intranasal lyophilized glucagon
    • Slama, G., Alamowitch, C., Desplanque, N., Letanoux, M. and Zirinis, P., A new non-invasive method for treating insulin reaction: Intranasal lyophilized glucagon, Diabetologia, 33 (1990) 671-674.
    • (1990) Diabetologia , vol.33 , pp. 671-674
    • Slama, G.1    Alamowitch, C.2    Desplanque, N.3    Letanoux, M.4    Zirinis, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.