Stabilization of insulin by alkylmaltosides. A. Spectroscopic evaluation

International Journal of Pharmaceutics

Volumn 132, Issue 1-2, 1996, Pages 107-113

  Hovgaard, Lars ^a,c   Jacobs, Harvey ^a   Mazer, Norman A ^b   Kim, Sung Wan ^a  

^a UNIVERSITY OF UTAH   (United States)

^b TheraTech Inc   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Aggregation; Alkylmaltosides; Insulin; Laser light scattering; Peptide; Self association

Indexed keywords

DECYLMALTOSIDE; DODECYLMALTOSIDE; DRUG ADDITIVE; HEXADECYLMALTOSIDE; INSULIN; MALTOSE; OCTADECYLMALTOSIDE; OCTYLMALTOSIDE; TETRADECYLMALTOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; DRUG STABILITY; HYDRODYNAMICS; LIGHT SCATTERING; MICELLE; PRIORITY JOURNAL;

EID: 0030001515     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04371-3     Document Type: Article

References (28)

1. Arquilla, E.R., Thiene, P., Brugman, T., Ruess, W. and Sugiyama, R., Effects of zinc ion on the conformation of antigenic determinants on insulin. Biochem. J., 175 (1978) 289-297.
2. Baker, E.N., Blundell, T.L., Cutfield, J.F., Cutfield, S.M., Dodson, E.J., Dodson, G.G., Hodgkin, D.M.C., Hubbard, R.E., Isaacs, N.W., Reynolds, C.D., Sakabe, K., Sakabe, N. and Vijayan, N.M., The structure of 2Zn pig insulin crystals at 1.5 Å resolution. Phil. Trans. R. Soc. Trans. Lond., B-319 (1988) 369-456.
3. Blundell, T.L., Cutfield, J.F., Cutfield, S.M., Dodson, E.J., Dodson, G.G., Hodgkin, D.C. and Mercola, D.A., Three-dimensional atomic structure of insulin and its relationship to activity. Diabetes, 21 (1972) 492-505.
4. Bohidar, H.B. and Geissler, E., Static and dynamic light scattering from dilute insulin solutions. Biopolymers, 23 (1984) 2407-2417.
5. Brange, J., Stability of Insulin, Kluwer Academic Publishers, Boston, 1994, pp. 7-59.
6. Brange, J., Galenics of Insulin, Springer-Verlag, Berlin Heidelberg, 1987.
7. Brange, J., Ribel, U., Hansen, J.F., Dodson, G., Hansen, M.T., Havelund, S., Melberg, S.G., Norris, F., Norris, K., Snel, L., Sørensen, A.R. and Voigt, H.O., Monomeric insulins obtained by protein engineering and their medical implications. Nature, 133 (1988) 679-682.
8. Chawla, A.S., Hinberg, I., Biais, P. and Johnson, D., Aggregation of insulin, containing surfactants, in contact with different materials. Diabetes, 34 (1985) 420-424.
9. Cohen, D.E., Fisch, M.R. and Carey, M.C., Principles of laser light-scattering spectroscopy: Applications to the physicochemical study of model and native biles. Hepatology, 12 (1990) 113s-122s.
10. De Meyts, P., Van Obberghen, E., Roth, J., Wollmer, A. and Brandenburg, D., Mapping of the residues responsible for the negative cooperatively of the receptor-binding region of insulin. Nature, 273 (1978) 504-509.
11. Eisenberg, D. and Crothers, D., Physical chemistry, Benjamin Cummings, Menlo Park, 1979, p.634.
12. Goldman, J. and Carpenter, F.H., Zink binding, circular dichroism, and equilibrium sedimentation studies on insulin (bovine) and several of its derivatives. Biochemistry, 13 (1974) 4566-4574.
13. Grau, U., Chemical stability of insulin in a delivery system environment. Diabetology, 28 (1985) 458-463.
14. Hovgaard, L., Mack, E.J. and Kim, S.W., Insulin stabilization and GI absorption. J. Control. Rel., 19 (1992) 99-108.
15. Hovgaard, L., Insulin Stabilization and Gastrointestinal Absorption, Ph.D. Thesis, University of Utah, Salt Lake City, Utah, 1991.
16. Hvidt, S., Insulin association in neutral solutions studied by light scattering. Biophys. Chem., 39 (1991) 205-213.
17. Lougheed, W.D., Albisser, A.M., Martindale, H.M., Chow, J.C. and Clement, J.R., Physical stability of insulin formulations. Diabetes, 32 (1983) 424-432.
18. Marshall, G.R., Beitch, J., Ellis, R.A. and Fritsch, J.M., Macromolecular modelling system: The insulin dimer. Fiftieth anniversary insulin symposium, Indianapolis, Indiana, (1971) 506-508.
19. Martindale, H., Marsh, J., Hallett, F.R. and Albisser, A.M., Examination of insulin formulations using quasi-elastic light scattering. Diabetes, 31 (1982) 364-366.
20. Mazer, N.A., Benedek, G.B. and Carey, M.C., An investigation of the micellar phase of sodium dodecyl sulfate in aqueous sodium chloride solutions using quasi elastic light scattering spectroscopy. J. Phys. Chem., 80 (1976) 1075-1084.
21. Mazer, N.A., Laser light scattering in micellar systems. In Pecora, R. (ed), Dynamic Light Scattering, Plenum Press, New York, 1985, pp. 305-346.
22. Mysels, K.J. and Princen, L.H., Light scattering by some lauryl sulfate solutions. J. Colloid. Sci., 63 (1959) 1696-1700.
23. Pullen, R.A., Lindsay, D.G., Wood, S.P., Tickle, I.J., Blundell, T.L., Wollmer, A., Krail, D., Brandenburg, D., Zahn, H., Gliemann, J. and Gammeltoft, S., Receptor-binding region of insulin. Nature, 259 (1976) 369-373.
24. Rosen, M.J., Surfactants and Interfacial Phenomena, John Wiley and Sons, New York, 1989.
25. Sato, S., Ebert, C.D. and Kim, S.W., Prevention of insulin self-association and surface adsorption. J. Pharm. Sci., 72 (1983) 228-232.
26. Schrader, E. and Pfeiffer, E.F., The influence of motion and temperature upon the aggregational behavior of soluble insulin formulations investigated by high performance liquid chromatography. J. Liq. Chromat., 8 (1985) 1139-1157.
27. Sluzky, V., Tamada, J.A., Klibanov, A.M. and Langer, R., Kinetics of insulin aggregation in aqueous solutions in presence of hydrophobic interfaces. Pros. Nat. Acad. Sci. USA, 88 (1991) 9377-9381.
28. Thurow, H. and Geisen, K., Stabilization of dissolved proteins against denaturation at hydrophobic surfaces. Diabetology, 27 (1984) 212-218.