Subinhibitory concentrations of β-lactams and other cell-wall antibiotics inhibit listeriolysin production by Listeria monocytogenes

International Journal of Antimicrobial Agents

Volumn 7, Issue 1, 1996, Pages 75-81

  Nichterlein, Thomas ^a   Domann, Eugen ^b   Kretschmar, Marianne ^a   Bauer, Martin ^a   Hlawatsch, Alexander ^a   Hof, Herbert ^a   Chakraborty, Trinad ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

L. monocytogenes; Listeriolysin; Subinhibitory antibiotic concentrations

Indexed keywords

AMPICILLIN; AZTREONAM; BETA LACTAM ANTIBIOTIC; CEFEPIME; CEFOTAXIME; CYCLOSERINE; FOSFOMYCIN; LISTERIOLYSIN; PENICILLIN G; POLYMYXIN B; TYROTHRICIN; VANCOMYCIN;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; LISTERIA MONOCYTOGENES; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0030001465     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/0924-8579(96)00014-3     Document Type: Article

References (23)

1. Lorian V, Gemmel CG. Effect of low antibiotic concentrations on bacteria: effects on ultrastructure, virulence, and susceptibility to immunodefenses. In: Lorian V (ed) Antibiotics in Laboratory Medicine. Williams and Wilkins, London, 1991, pp. 493-555.
2. Brook I, Gober AE, Leyva F. In vitro and in vivo effects of penicillin and clindamycin on expression of group A beta-hemolytic streptococcal capsule. Antimicrob Agents Chemother 1995;39:1565-1568.
3. Hacker J, Ott M, Hof H. Effects of low, subinhibitory concentrations of antibiotics on expression of a virulence gene cluster of pathogenic Escherichia coli by using a wild-type gene fusion. Int J Antimicrob Agents 1993;2:263-270.
4. Müller-Alouf H, Geoffroy C, Alouf JE. Comparative study of the inhibitory effects of amoxicillin and macrolides on the production of erythrogenic (pyrogenic) Exotoxin A and Streptolysin O by Streptococcus pyogenes. 7th European Congress of Clinical Microbiology and Infectious Diseases, March, 26-30, Vienna, 1995.
5. Shibl AM. Effect of antibiotics on production of enzymes and toxins by microorganisms. Rev Inf Dis 1983;5:865-875.
6. Mandell LA, Afnan M. Mechanisms of interaction among subinhibitory concentrations of antibiotics, human polymorphonuclear neutrophils, and gram-negative bacilli. Antimicrob Agents Chemother 1987;35:1291-1297.
7. Michel J, Ferne M, Rotenberg M. Effets de concentrations subinhibitrices d'antibiotiques sur la virulence de Streptocoques hemolytiques du groupe A. Pathol Biol Paris 1983;31:528-532.
8. Leimeister-Wächter M, Domann E, Chakraborty T. The Expression of virulence genes in Listeria monocytogenes is thermoregulated. J Bacteriol 1992;174:947-952.
9. Leimeister-Wächter M, Chakraborty T. Detection of the listeriolysin, the thiol-dependent hemolysin in Listeria monocytogenes, Listeria ivanovii, and Listeria seeligeri. Infect Immun 1989; 57:2350-2357.
10. Wellek S. Statistische Methoden zum Nachweis der Aquivalenz. Fischer, Stuttgart, 1994, pp. 57-62.
11. Jones EM, Mac Gowan AP. Antimicrobial chemotherapy of human infection due to Listeria monocytogenes. Eur J Clin Microbiol Infect Dis 1995;14:165-175.
12. Armstrong D. Listeria monocytogenes. In: Mandell GL, Douglas RG, Bennett JE (eds) Principles and Practice of Infectious Diseases. Churchill Livingstone, New York, 1990, pp. 1587-1593.
13. Hof H. Intracellular microorganisms: a particular problem for chemotherapy. Infection 1991;19(Suppl 4):193-194.
14. Conlan W., North R. Neutrophil-mediated lysis of infected hepatocytes. ASM News 1993;59:563-567.
15. Portnoy DA, Chakraborty T, Goebel W, Cossart P. Molecular determinants of Listeria monocytogenes pathogenesis. Infect Immun 1992;60:1263-1270.
16. Lorian V. Low concentrations of antibiotics. J Antimicrob Chemother 1985;15(Suppl A):15-26.
17. Zhanel GG, Hoban DJ, Harding GKM. Subinhibitory antimicrobial concentrations: A review of in vitro and in vivo data. Can J Infect Dis 1992;3:193-201.
18. Franklin TJ, Snow GA. Biochemistry of Antimicrobial Action. Chapman and Hall, London, 1989, pp. 20-72.
19. Vicente MF, Pérez-Diaz JC, Baquero F, de Pedro MA, Berenguer J. Penicillin-binding protein 3 of Listeria monocytogenes as the primary lethal target for β-lactams. Antimicrob Agents Chemother 1990;539-542.
20. Pierre J, Boisivon A, Gutmann L. Alteration of PBP 3 entails resistance to Imipenem in Listeria monocytogenes. Antimicrob Agents Chemother 1990;1695-1698.
21. Hakenbeck R, Hof H. Relatedness of penicillin-binding proteins from various Listeria species. FEMS Microbiol Lett 1991;84:191-196.
22. Domann E, Wehland J, Niebuhr K, Haffner C, Leimeister-Wächter M., Chakraborty T. Detection of prfA-independent promoter responsible for listeriolysin gene expression in mutant Listeria monocytogenes strains lacking the prfA regulator. Inf Immun 1993;61:3073-3075.
23. Kreft J, Bohne J, Gross R, Kestler H, Sokolovic Z, Goebel W. Control of Listeria monocytogenes virulence by the transcriptional regulator prfA. In: Rappuoli R, Scarlato, Aricò B (eds) Signal Transduction and Bacterial Virulence. R.G. Landes Company, pp. 130-142.