Mechanism of increasing dystrophin-positive myofibers by myoblast transplantation: Study using mdx/β-galactosidase transgenic mice

Acta Neuropathologica

Volumn 91, Issue 5, 1996, Pages 489-493

  Kinoshita, Ikuo ^a   Vilquin, Jean Thomas ^a   Tremblay, Jacques P ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Duchenne muscular dystrophy; mdx mouse; Myoblast transplantation; Transgenic mouse

Indexed keywords

BETA GALACTOSIDASE; DYSTROPHIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUSION; CELL PROLIFERATION; CELL TRANSPLANTATION; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; HOST CELL; IRRADIATION; MALE; MOUSE; MUSCLE CELL; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SATELLITE CELL;

ANIMALS; BETA-GALACTOSIDASE; DYSTROPHIN; MALE; MICE; MICE, INBRED MDX; MICE, TRANSGENIC; MUSCLE, SKELETAL; MYOFIBRILS;

EID: 0029999083     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050456     Document Type: Article

References (37)

1. Arahata E, Ishiura S, Ishiguro T, Tshukahara T, Suhara Y, Eguchi C, Ishihara T, Nonaka I, Ozawa E, Sugita H (1988) Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide. Nature 333: 861-863
2. Beam KG (1988) Duchenne muscular dystrophy: localization of the gene product. Nature 333: 798-799
3. Bodrug SE, Ray PN, Gonzalez IL, Schmickel RD, Sylvester JE, Worton RG (1987) Molecular analysis of a constitutional X-autosome translocation in a female with muscular dystrophy. Science 237: 1620-1634
4. Bonilla E, Samitt CE, Miranda AF, Hays AP, Salviati G, Dimauro S, Kunkel LM, Huffman EP, Rowland LP (1988) Duchenne muscular dystrophy: deficiency of dystrophin at the muscle cell surface. Cell 54: 447-452
5. Bulfield G, Siller WG, Wight PAL, Moore KJ (1984) X chromosome-linked muscular dystrophy (mdx) in the mouse. Proc Natl Acad. Sci USA 81: 1189-1192
6. Cossu G, Zani B, Coletta M, Bouche M, Pacifict M, Molinaro M (1980) In vitro differentiation of satellite cells isolated from normal and dystrophic mammalian muscles. A comparison with embryonic myogenic cells. Cell Differ 9: 357-368
7. Grounds MD, McGeachie JK (1992) Skeletal muscle regeneration after crush injury in dystrophic mdx mice. Muscle Nerve 15: 580-586
8. Grounds MD, Lai Y, Fan JC, Codling JC, Beilharz MW (1991) Transplantation in the mouse model: the use of a Y-chromosome-specific DNA clone to identify donor cells in situ. Transplantation 52: 1101-1005
9. Hallauer PL, Bradshow HL, Hasting KEM (1993) Complex fiber-type-specific expression of fast skeletal muscle troponin I gene constructs in transgenic mice. Development 119: 691-701
10. Huffman EP, Kunkel LM, Brown RH (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51: 919-928
11. Hoffman EP, Hudecki MS, Rosenberg PA, Pollina CM, Kunkel M (1988) Cell and fiber-type distribution of dystrophin. Neuron 1: 411-420
12. Huard J, Labrecque C, Dansereau G, Robitaille L, Tremblay JP (1991) Dystrophin expression in myorubes formed by the fusion of normal and dystrophic myoblasts. Muscle Nerve 14: 178-182
13. Huard J, Fortier LP, Dansereau G, Labrecque C, Tremblay JP (1992) A light and electron microscopic study of dystrophin localization at the mouse neuromuscular junction. Synapse 10: 83-93
14. Huard J, Ascadi G, Jani A, Massie B, Karpati G (1994) Gene transfer into skeletal muscles by isogenic myoblasts. Hum Gene Ther 5: 949-958
15. Huard J, Roy R, Guérette B, Verreault S, Tremblay M, Tremblay JP (1994) Human myoblast transplantation in immunodeficient and immunosuppressed mice: evidence of rejection. Muscle Nerve 17: 224-234
16. Huard J, Verreault S, Roy R, Tremblay M, Tremblay JP (1994) High efficiency of muscle regeneration after human myoblast clone transplantation in SCID mice. J Clin Invest 93: 586-599
17. Irintchev A, Zweyer M, Wernig A (1995) Cellular and molecular reactions in mouse muscles after myoblast implantation. J Neurocytol 24: 319-331
18. Karpati G, Pouliot Y. Zubrzycka-Gaam E, Carpenter S, Ray PN, Worton RG, Holland P (1989) Dystrophin is expressed in mdx skeletal muscle fibers after normal myoblast implantation. Am J Pathol 135: 27-32
19. Kinoshita I, Huard J, Tremblay JP (1994) Utilization of myoblasts from transgenic mice to evaluate the efficacy of myoblast transplantation. Muscle Nerve 17: 975-980
20. Kinoshita I, Vilquin JT, Guérette B, Asselin I, Roy R, Tremblay JP (1994) Very efficient myoblast allotransplantation in mice under FK506 immunosuppression. Muscle Nerve 17: 1407-1415
21. Kinoshita I, Vilquin JT, Tremblay JP (1995) Pretreatment of myoblast cultures with basic fibroblast growth factor increases the efficacy of their transplantation in mdx mice. Muscle Nerve 18: 834-841
22. Koenig M, Hoffman EP, Bertelson CJ, Monaco AP, Feener C, Kunkel LM (1987) Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals. Cell 50: 509-517
23. Law PK, Goodwin TS, Wang MG (1988) Normal myoblast injections provide genetic treatment for murine dystrophy. Muscle Nerve 11: 525-533
24. Morgan JE, Watt DJ, Sloper JC, Partridge TA (1988) Partial correction of an inherited defect of skeletal muscle by grafts of normal mice precursor cells. J Neurol Sci 86: 137-147
25. Morgan JE, Hoffman EP, Partridge TA (1990) Normal myogenic cells from newborn mice restore normal histology to degenerating muscle of the mdx mouse. J Cell Biol 111: 2437-2449
26. Morgan JE, Pagel CN, Sherratt T, Partridge TA (1993) Long-term persistence and migration of myogenic cells injected into pre-irradiated muscles of mdx mice. J Neurol Sci 115: 191-200
27. Partridge TA, Morgan JE, Coulton GR, Hoffman EP, Kunkel LM (1989) Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts. Nature 337: 176-179
28. Quinlan JG, Lyden SP, Cambier DM, Johnson S, Michaels SE, Denman DL (1995) Radiation inhibition of mdx mouse muscle regeneration: dose and age factors. Muscle Nerve 18: 201-206
29. Satoh A, Labrecque C, Tremblay JP (1993) Use of fluorescent latex microspheres (FLMs) to follow the fate of transplanted myoblasts. J Histochem Cytochem 41: 1579-1582
30. Shimizu T, Mannen T, Matsumura K, Sunada Y (1989) Dense immunostainings on both neuromuscular and myotendon junctions with an anti-dystrophin monoclonal antibody. Biomed Res 10: 405-409
31. Sicinski P, Rider-Cook AS, Seng Y, Barnard EG, Darlison M, Barnard J (1989) The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science 244: 1578-1579
32. Sugita H, Arahata K, Ishiguro T, Suhara Y, Thukahara T, Ishiura S, Eguchi C, Nonaka I, Ozawa E (1988) Negative immunostaining of Duchenne muscular dystrophy (DMD) and mdx muscle surface membrane with antibody against synthetic peptide fragments predicted from DMD cDNA. Proc Jpn Acad 64: 37-39
33. Vilquin JT, Asselin I, Guérette B, Kinoshita I, Roy R, Tremblay JP (1995) Successful myoblast transplantation in mdx mice using rapamycin. Transplantation 59: 422-426
34. Vilquin JT, Kinoshita I, Roy R, Tremblay JP (1995) Cyclophosphamide immunosuppression does not permit successful myoblast allotransplantation. Neuromuscul Disord 5: 511-517
35. Wakeford S, Watt DJ, Partridge TA (1991) X-irradiation improves mdx mouse muscle as a model of myofiber loss in DMD. Muscle Nerve 14: 42-50
36. Wernig A, Irintchev A (1995) "Bystander" damage of host muscle caused by implantation of MHC-compatible myogenic cells. J Neurol Sci 130: 190-196
37. Wernig A, Irintchev A, Lange G (1995) Functional effects of myoblast implantation into histoincompatible mice with or without immunosuppression. J Physiol (Lond) 484: 493-504