Overcoming of P-glycoprotein mediated vincristine resistance of L1210/VCR mouse leukemic cells could be induced by pentoxifyline but not by theophylline and caffeine

Neoplasma

Volumn 43, Issue 1, 1996, Pages 11-15

  Stefankova Z ^a   Barancik M ^a   Breier, A ^b  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

^b INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; GLYCOPROTEIN P; PENTOXIFYLLINE; THEOPHYLLINE; VINCRISTINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LEUKEMIA; LEUKEMIA CELL LINE; MOUSE; NONHUMAN;

EID: 0029998787     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. BARANČÍK, M., DOČOLOMANSKÝ, P., SLEZÁK, J., BREIER, A.: Overcoming of vincristine resistance in L1210/VCR cells by several corticosteroids. Collateral sensitivity of resistant cells. Neoplasma, 40, 1993, 21-25.
2. 2+-entry blockers, neuroleptics, and local anaesthetics on P-glycoprotein-mediated vincristine resistance of L1210/VCR mouse leukemic cell line. Drugs Exptl. Clin. Res., 20, 1994, 13-18.
3. BORSELLINO, N., CRESCIMANNO, M., LEONARDI, V., D'ALESANDRO, N.: Effect of 8-chloro-cyclic adenosine monophosphate on the growth and sensitivity to doxorubicin of multidrug-resistant tumour cell lines. Pharmacol. Res., 30, 1994, 81-90.
4. BREIER, A., BARANČÍK, M., ŠTEFANKOVÁ, V., UHRÍK, B., TRIBULOVÁ, N.: Effect of pentoxifylline on P-glycoprotein mediated vincristine resistance of L1210 mouse leukemic cell line. Neoplasma, 41, 1994, 297-303.
5. BREIER, A., ŠTEFANKOVÁ, Z., BARANČÍK, M., TRIBULOVÁ, N.: Time dependence of [3H]-vincristine accumulation by L1210 mouse leukemic cells. Effect of P-glycoprotein overexpression. Gen. Physiol. Biophys., 13, 1994, 287-298.
6. CANO-GAUCI, D.F., RIORDAN, J.R.: Collateral sensitivity of multidrug resistant cells. In: Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells. Ed.: Robinson, I.B., Plenum Publishing Corporation 1991, 337-347.
7. CHAPMAN, R.A., TUNSTALL, J.: Pharmacology of calcium uptake and release from the sarcoplasmic reticulum: Sensitivity to methylxanthines and ryanodine. In: Handbook of Experimental Pharmacology: Calcium in Drug Actions. Ed.: Baker, P.F. , Springer Verlag 1988, 199-216.
8. CHITNIS, M.P., VILADKAR, A.B., JUVEKAR, A.B.: Inhibition of DNA biosynthesis by vincristine and pentoxifylline in murine P388 leukemia cells resistant to doxorubicin. Neoplasma, 37, 1990, 619-626.
9. HILL, B.T.: Collateral sensitivity and cross resistance. In: Antitumor Drug Resistance. Eds: Fox, B.W., Fox, M. , Springer Verlag 1984, 673-697.
10. HURŇÁK, O., ZACHAROVÁ, D., ZACHAR, J.: Effect of pentoxifylline on physiological mechanism of excitation contraction coupling in crayfish skeletal muscle. Slovakofarma Rev., 3, 1993, 110-116.
11. LUGNIER, C., GAUTHIER, C., LE BEC, A., SOUSTRE, H.: Cyclic nucleotide phosphodiesterases from frog atrial fibres: Isolation and drug sensitivities. Am. J. Physiol., 262, 1992, H654-H660.
12. MIZSUTANI, Y., BONAVIDA, B., NIO, Y., YOSHIDA, O.: Overcomming TNF-alfa and drug resistance of human renal cell carcinoma by treatment with pentoxifylline in combination with TNF-alfa or drugs: The role ofTNF-alfa mRNA downregulation in tumor cell sensitization. J. Urol., 151, 1994, 1697-1702.
13. POLEKOVÁ, L., BARANČÍK, M., MRÁZOVÁ, T., PIRKER, R., WALLNER, J., SULOVÁ, Z., BREIER, A.: Adaption of mouse leukemia cells L1210 to vincristine. Evidence for expression of P-glycoprotein. Neoplasma, 39, 1992, 73-77.
14. SAKAI, R., KONNO, K., YAMAMOTO, Y., SANAE, F., TAKAGI, K., HASEGAWA, T., IWASAKI, N., KAKIUCHI, M., KATO, H., MIYAMOTO, K.: Effect of alkyl substitutions of xanthine skeleton on bronchodilatation. J. Med. Chem., 30, 1992, 4039-4044.
15. SAMLASKA, C.P., WINFIELD, E.A.: Pentoxifylline. J. Am. Acad. Dermacol., 30, 1994, 603-621.
16. SEMMLER, J., GEBERT, U., EISENHUT, T., MOELLER, J., SCHONHARTING, M.M., ALLERA, A., ENDRES, S.: Xanthine derivatives: Comparison between suppression of tumour necrosis factor-alfa production and inhibition of cAMP phosphodiesterase activity. Immunology, 78, 1993, 520-525.
17. SEMMLER, J., WACHTEL, H., ENDRES, S.: The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-alfa production by human mononuclear cells. J. Immunopharmacol., 15, 1993, 409-413.
18. VILADKAR, A., CHITNIS, M.: In vitro effect of pentoxifylline and doxorubicin on cell survival and DNA damage in sensitive and MDR-P388 leukemia cells. Cancer Biother., 9, 1994, 143-151.