Pharmacokinetics of cyclizine following intravenous administration to human volunteers

European Journal of Pharmaceutical Sciences

Volumn 4, Issue 5, 1996, Pages 301-306

  Walker, R B ^a   Kanfer, I ^a  

^a RHODES UNIVERSITY   (South Africa)

Author keywords

Cyclizine; Human; Norcyclizine; Pharmacokinetics; Serum; Urine

Indexed keywords

CYCLIZINE;

ADULT; ARTICLE; CLINICAL TRIAL; DRUG CLEARANCE; DRUG EXCRETION; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL;

EID: 0029998042     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/0928-0987(96)00177-7     Document Type: Article

References (4)

1. Benet, L.Z. and Galeazzi, R.L. (1979) Noncompartmental determination of the steady state volume of distribution. J Pharm. Sci. 68, 1071-1074.
2. Declaration of Helsinki, I, II, III and IV, Recommendations guiding physicians in biomedical research involving human subjects. Adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964 (1) and amended by the 29th World Medical Assembly, Tokyo, Japan, October 1975 (II), the 35th World Medical Assembly, Venice, Italy, October 1983 (III) and the 41st World Medical Assembly. Hong Kong, September 1989 (IV).
3. Gibaldi, M. and Perrier, D. (1982) Pharmacokinetics (2nd ed.) Marcel Dekker, New York.
4. Griffin, D.S. and Baselt, R.C. (1984) Blood and urine concentrations of cyelizine by nitrogen-phosphorus gas-liquid chromatography. J Anal. Toxicol. 8, 97-99.