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Volumn 23, Issue 3, 1996, Pages 257-261

Modification of antibody isoelectric point affects biodistribution of 111-indium-labeled antibody

Author keywords

biodistribution; DTPA; isoelectric focussing; isoelectric pain; rabbit antihuman serum albumin

Indexed keywords

ANTIBODY IN 111; HUMAN SERUM ALBUMIN; PENTETIC ACID; UNCLASSIFIED DRUG;

EID: 0029998012     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/0969-8051(95)02057-8     Document Type: Article
Times cited : (21)

References (24)
  • 2
    • 0026509312 scopus 로고
    • The mechanism of hepatic uptake of a radiolabelled monoclonal antibody
    • Boyle C. C., Paine A. J. and Mather S. J. (1992) The mechanism of hepatic uptake of a radiolabelled monoclonal antibody. Int. J. Cancer 50, 912-917.
    • (1992) Int. J. Cancer , vol.50 , pp. 912-917
    • Boyle, C.C.1    Paine, A.J.2    Mather, S.J.3
  • 3
    • 0014703156 scopus 로고
    • Induction of rabbit antibody with molecular uniformity after immunization with group c streptococci
    • Eichmann K., Lackland H., Hood L. and Krause R. M. (1970) Induction of rabbit antibody with molecular uniformity after immunization with Group C streptococci. J. Exp. Med. 131, 207-221.
    • (1970) J. Exp. Med. , vol.131 , pp. 207-221
    • Eichmann, K.1    Lackland, H.2    Hood, L.3    Krause, R.M.4
  • 4
    • 0023178084 scopus 로고
    • New method for the chelation of indium-111 to monoclonal antibodies: Biodistribution and imaging of athymic mice bearing human colon-carcinoma xenografts
    • Esteban J. M., Schlom J., Gansow O. A., Atcher R. W., Brechbiel M. W., Simpson D. E. and Colcher D. (1987) New method for the chelation of indium-111 to monoclonal antibodies: biodistribution and imaging of athymic mice bearing human colon-carcinoma xenografts. J. Nucl. Med. 28, 861-870.
    • (1987) J. Nucl. Med. , vol.28 , pp. 861-870
    • Esteban, J.M.1    Schlom, J.2    Gansow, O.A.3    Atcher, R.W.4    Brechbiel, M.W.5    Simpson, D.E.6    Colcher, D.7
  • 6
    • 0023609810 scopus 로고
    • Sialic acid mediates the initial binding of positively charged inorganic particles to alveolar macrophage membrane
    • Gallagher J. E. George G. and Brody A. R. (1987) Sialic acid mediates the initial binding of positively charged inorganic particles to alveolar macrophage membrane. Am. Rev. Respir. Dis. 135, 1345-1352.
    • (1987) Am. Rev. Respir. Dis. , vol.135 , pp. 1345-1352
    • Gallagher, J.E.1    George, G.2    Brody, A.R.3
  • 7
    • 0028199862 scopus 로고
    • Semipreparative isoelectrophoresis of DTPA-conjugated antibody leads to isolation of antibody isoforms with different immunoreactivities
    • Gangopadhyay A., Saravis C. A. and Kassis A. I. (1994a) Semipreparative isoelectrophoresis of DTPA-conjugated antibody leads to isolation of antibody isoforms with different immunoreactivities. J. Nucl. Biol. Med. 38, 61-67.
    • (1994) J. Nucl. Biol. Med. , vol.38 , pp. 61-67
    • Gangopadhyay, A.1    Saravis, C.A.2    Kassis, A.I.3
  • 9
    • 0021074173 scopus 로고
    • The preparation of DTPA-coupled antibodies radiolabeled with metallic radionuclides: An improved method
    • Hnatowich D. J., Childs R. L., Lanteigne D. and Najafi A. (1983a) The preparation of DTPA-coupled antibodies radiolabeled with metallic radionuclides: an improved method. J. Immunol. Meth. 65, 147-157.
    • (1983) J. Immunol. Meth. , vol.65 , pp. 147-157
    • Hnatowich, D.J.1    Childs, R.L.2    Lanteigne, D.3    Najafi, A.4
  • 11
    • 0028034313 scopus 로고
    • Application of high affinity binding concept to radiolabel avidin with Tc-99m labeled biotin and the effect of pi on biodistribution
    • Jeong J. M., Kinuya S., Paik C. H., Saga T., Sood V. K., Carrasquillo J. A., Numann R. D. and Reynolds J. C. (1994) Application of high affinity binding concept to radiolabel avidin with Tc-99m labeled biotin and the effect of pi on biodistribution. Nucl. Med. Biol. 21(7), 935-940.
    • (1994) Nucl. Med. Biol. , vol.21 , Issue.7 , pp. 935-940
    • Jeong, J.M.1    Kinuya, S.2    Paik, C.H.3    Saga, T.4    Sood, V.K.5    Carrasquillo, J.A.6    Numann, R.D.7    Reynolds, J.C.8
  • 14
    • 0022556055 scopus 로고
    • Determination of true immunoreactive fraction of monoclonal antibodies after radiolabeling
    • Edited by Langone J. J. and Van Vunakis H., Academic Press, Inc., Orlando, FL
    • Lindmo T. and Bunn P. A., Jr. (1986) Determination of true immunoreactive fraction of monoclonal antibodies after radiolabeling. In Methods in Enzymology (Edited by Langone J. J. and Van Vunakis H.), Vol. 121, pp. 678-691. Academic Press, Inc., Orlando, FL.
    • (1986) Methods in Enzymology , vol.121 , pp. 678-691
    • Lindmo, T.1    Bunn P.A., Jr.2
  • 15
    • 33751330608 scopus 로고
    • The determination of enzyme dissociation constants
    • Lineweaver H. and Burk D. (1934) The determination of enzyme dissociation constants. J. Am. Chem. Soc. 56, 658-666.
    • (1934) J. Am. Chem. Soc. , vol.56 , pp. 658-666
    • Lineweaver, H.1    Burk, D.2
  • 16
    • 0021169796 scopus 로고
    • Accessibility of circulating immunoglobulin G to the extravascular compartment of solid rat tumors
    • O'Connor S. W. and Bale W. F. (1984) Accessibility of circulating immunoglobulin G to the extravascular compartment of solid rat tumors. Cancer Res. 44, 3719-3723.
    • (1984) Cancer Res. , vol.44 , pp. 3719-3723
    • O'Connor, S.W.1    Bale, W.F.2
  • 18
    • 0018974089 scopus 로고
    • The development and use of radiolabeled antitumor antibodies
    • Pressman D. (1980) The development and use of radiolabeled antitumor antibodies. Cancer Res. 40, 2960-2964.
    • (1980) Cancer Res. , vol.40 , pp. 2960-2964
    • Pressman, D.1
  • 19
    • 0025345366 scopus 로고
    • Uptake of indium-111 in the liver of mice following administration of indium-111-DTPA-labelled monoclonal antibodies: Influence of labeling parameters, and antibody dose
    • Schuhmacher J., Klivenyi G., Matys R., Kirchgebner H., Hause H., Maier-Borst W. and Matzku S. (1990) Uptake of indium-111 in the liver of mice following administration of indium-111-DTPA-labelled monoclonal antibodies: influence of labeling parameters, and antibody dose. J. Nucl. Med. 31, 1084-1093.
    • (1990) J. Nucl. Med. , vol.31 , pp. 1084-1093
    • Schuhmacher, J.1    Klivenyi, G.2    Matys, R.3    Kirchgebner, H.4    Hause, H.5    Maier-Borst, W.6    Matzku, S.7
  • 20
    • 0023126033 scopus 로고
    • Surface charge of resident, elicited, and activated mouse peritoneal macrophages
    • Silva Filho F. C., Santos A. B. S., de Carvalho T. M. U. and de Souza W. (1987) Surface charge of resident, elicited, and activated mouse peritoneal macrophages. J. Leukoc. Biol. 41, 143-149.
    • (1987) J. Leukoc. Biol. , vol.41 , pp. 143-149
    • Silva Filho, F.C.1    Santos, A.B.S.2    De Carvalho, T.M.U.3    De Souza, W.4
  • 21
    • 0027175427 scopus 로고
    • Biodistribution of anti-CEA F(ab′)2 fragments conjugated with chelating polymers: Influence of conjugate electron charge on tumor uptake and blood clearance
    • Slinkin M. A., Curtet C., Faivre-Chauvet A., Sai-Maurel C., Gestin J. F., Torchilin V. P. and Chatal J. F. (1993) Biodistribution of anti-CEA F(ab′)2 fragments conjugated with chelating polymers: influence of conjugate electron charge on tumor uptake and blood clearance. Nucl. Biol. Med. 20, 443-452.
    • (1993) Nucl. Biol. Med. , vol.20 , pp. 443-452
    • Slinkin, M.A.1    Curtet, C.2    Faivre-Chauvet, A.3    Sai-Maurel, C.4    Gestin, J.F.5    Torchilin, V.P.6    Chatal, J.F.7
  • 23
    • 0023245450 scopus 로고
    • Monoclonal antibody modification with chelate-linked high-molecular weight polymers: Major increases in polyvalent cation binding without loss of antigen binding
    • Torchilin V. P., Klibanov A. L., Nossiff N. D., Slinkin M. A., Strauss H. W., Haber E., Smirnov V. N. and Khaw B. A. (1987) Monoclonal antibody modification with chelate-linked high-molecular weight polymers: major increases in polyvalent cation binding without loss of antigen binding. Hybridoma 6, 229-240.
    • (1987) Hybridoma , vol.6 , pp. 229-240
    • Torchilin, V.P.1    Klibanov, A.L.2    Nossiff, N.D.3    Slinkin, M.A.4    Strauss, H.W.5    Haber, E.6    Smirnov, V.N.7    Khaw, B.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.