Capillary electrophoretic purity method for the novel metal chelator TMT-NCS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 14, Issue 7, 1996, Pages 845-854

  Bullock, John ^a,b  

^a Sanofi Pharmaceuticals Inc   (United States)

^b ProClinical Inc   (United States)

Author keywords

Capillary electrophoresis; Metal chelator; Purity determination; Reversed phase liquid chromatography; TMT NCS

Indexed keywords

4 (3 ISOTHIOCYANATE 4 METHOXYPHENYL) 6,6 BIS [N,N DI(CARBOXYMETHYLAMINOMETHYL] 2,2,6,2 TERPYRIDINE TETRASODIUM; CHELATING AGENT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CAPILLARY ELECTROPHORESIS; DRUG DETERMINATION; DRUG PURITY; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

EID: 0029997835     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/0731-7085(95)01711-9     Document Type: Article

References (11)

1. US Patents 4637"988, 1987; 4""837""169, 1989.
2. A. Saha, K. Kross, E. Kloszewski, D. Upson, J. Toner, R. Snow, C. Black and V. Desai, J. Am. Chem. Soc., 115 (1993) 11032-11033.
3. International Patent WO 9""208""494-A2.
4. N. Iki, H. Hoshino and T. Yotsuyangi, J. Chromatogr., 652 (1993) 539-546.
5. S. Motomizu, S.-I. Nishimura, Y. Obata and H. Tanaka, Anal. Sci., 7 (supplement) (1991) 253-256.
6. N. Iki, H. Hoshino and T. Yotsuyangi, Chem. Lett., (1993) 701-704.
7. T. Saitoh, H. Hoshino and T. Yotsuyanagi, J. Chromatogr., 469 (1989) 175-181.
8. T. Saitoh, H. Hoshino and T. Yotsuyanagi, Anal. Sci., 7 (1991) 495-497.
9. S. Motomizu, M. Oshima, S.-Y. Matsuda, Y. Obata and H. Tanaka, Anal. Sci., 8 (1992) 619-625.
10. D. Swaile and M. Sepaniak. Anal. Chem., 63 (1991) 179-184.
11. B. Glassner, W. Friedl and E. Kenndler, J. Chromatogr., 680 (1994) 25-31.