Nursing home-acquired pneumonia: Treatment options

Drugs and Aging

Volumn 8, Issue 5, 1996, Pages 338-348

  Marrie, Thomas J ^a,b   Slayter, Kathryn L ^b,c  

^a DALHOUSIE UNIVERSITY   (Canada)

^b QUEEN ELIZABETH II HEALTH SCIENCES CENTRE   (Canada)

^c DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMPICILLIN; ANTIINFECTIVE AGENT; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; GENTAMICIN; INFLUENZA VACCINE; ISONIAZID; PENICILLIN G; PNEUMOCOCCUS VACCINE;

AGED; ANTIBIOTIC THERAPY; ANTIMICROBIAL THERAPY; BRONCHOSCOPY; CLINICAL TRIAL; COLITIS; DEATH; EMERGENCY WARD; HOSPITALIZATION; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LENGTH OF STAY; MALAISE; MEDICAL DECISION MAKING; MEDICAL RESEARCH; MYALGIA; NURSING HOME; NUTRITIONAL SUPPORT; ORAL DRUG ADMINISTRATION; PATIENT CARE; PNEUMONIA; PRIORITY JOURNAL; REVIEW; TREATMENT OUTCOME; TUBERCULOSIS;

EID: 0029997637     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-199608050-00003     Document Type: Review

References (64)

1. Olive KE, Berk SL. Infection in the nursing home. Clin Geriatr Med 1992; 8: 821-34
2. Marrie TJ. Epidemiology of community-acquired pneumonia in the elderly. Semin Respir Infect 1990; 5: 260-8
3. Marrie TJ, Durant J, Kwan C. Nursing home-acquired pneumonia: a case-control study. J Am Geriatr Soc 1986; 34: 697-702
4. Garb JL, Brown RB, Garb JR, et al. Differences in etiology of pneumonias in nursing home and community patients. JAMA 1978; 240: 2169-72
5. Marrie TJ, Durant H, Yates L. Community acquired pneumonia requiring hospitalization: 5-year prospective study. Rev Infect Dis 1989 Jul-Aug; 11 (4): 586-99
6. Phillips SL, Branaman-Phillips J. The use of intramuscular cefoperazone versus intramuscular ceftriaxone in patients with nursing home-acquired pneumonia. J Am Geriatr Soc 1993; 41: 1071-4
7. Drinka PJ, Gauerke C, Voeks S, et al. Pneumonia in a nursing home. J Gen Intern Med 1994; 9: 650-2
8. Chow CW, Senathiragah N, Rawji M, et al. Interim report on drug utilization review of community-acquired and nosocomial pneumonia: clinical bacteriological and radiological spectrum. Can J Infect Dis 1994; 5 Suppl. C: 20C-27C
9. Morris J. Physiological changes due to age: implications for respiratory drug therapy. Drugs Aging 1994; 4 (3): 207-20
10. Holas MA, DePippo KL, Reading MJ. Aspiration and relative risk of medical complications following stroke. Arch Neurol 1994; 51: 1501-3
11. Kilkuchi R, Watabe N, Konno T, et al. High incidence of silent aspiration in elderly patients with community-acquired pneumonia. Am J Respir Crit Care Med 1994; 150: 251-3
12. Homer J, Alberts MJ, Davison DN, et al. Swallowing in Alzheimer's disease. Alzheimer Dis Assoc Disord 1994; 8: 177-89
13. Fein AM. Pneumonia in the elderly: special diagnostic and therapeutic considerations. Med Clin North Am 1994 Sep; 78: 1015-33
14. Terpenning MS, Bradley SK, Wan JY, et al. Colonization and infection with antibiotic-resistant bacteria in a long-term care facility. J Am Geriatr Soc 1994; 42: 1062-9
15. Valenti WM, Trudel RG, Bentley DW. Factors predisposing Io oropharyngeal colonization with gram-negative bacilli in the aged. N Engl J Med 1978; 298: 1108-11
16. Falsey AE, Treanor JJ, Betts RF, et al. Viral respiratory infections in the institutionalized elderly: clinical and epidemiologic findings. J Am Geriatr Soc 1992; 40: 115-9
17. Mehr DR, Foxman B, Colombo P. Risk factors for mortality from lower respiratory infections in nursing home patients. J Fam Pract 1992; 34: 585-91
18. Ainslie N, Beisecker AE. Changes in decisions by elderly persons based on treatment description. Arch Intern Med 1994 Oct 10; 154: 2225-33
19. Tresch DD, Neahring JM, Duthie EH, et al. Outcomes of cardiopulmonary resuscitation in nursing homes: can we predict who will benefit? Am J Med 1993; 95: 123-30
20. Tsevan J, Cook F, Green ML, et al. Health values of the seriously ill. Ann Intern Med 1994; 122: 514-20
21. British Thoracic Society and Public Heallh Laboratory Service. Community-acquired pneumonia in adults in British hospitals in 1982-1983: a survey of aetiology, mortality, prognostic factors and outcome. The British Thoracic Society and the Public Health Laboratory Service. Q J Med 1987; 62: 195-220
22. Gilbert K, Fine MJ. Assessing prognosis and predicting patient outcomes in community-acquired pneumonia. Semin Respir Infect 1994; 9: 140-52
23. Norman DC. Pneumonia in the elderly: empiric antimicrobial therapy. Geriatrics 1991 Dec; 46: 26-32
24. Mulligan T. Parenteral antibiotic therapy for patients in nursing homes. Rev Infect Dis 1991; 13 Suppl. 2: S180-3
25. Mandell LA, Niederman M. The Canadian Community Acquired Pneumonia Consensus Conference Group. Antimicrobial treatment of community-acquired pneumonia in adults: a conference report. Can J Infect Dis 1993 Jan/Feb: 4 (1): 25-8
26. Lefevre F, Feinglass J, Potts S, et al. Iatrogenic complications in higher-risk, elderly patients. Arch Intern Med 1992 Oct: 152: 2074-80
27. Esposito AL. Pneumonia in the elderly. Am Fam Physician 1989; 40 Suppl. 5: 23S-32S
28. Donowitz GR, Mandell GL. Drug therapy: betalactam antibiotics (1). N Engl J Med 1988; 318 (7): 419-26
29. Donowitz GR, Mandell GL. Drug therapy: betalactam antibiotics (2). N Engl J Med 1988; 318 (8): 490-500
30. Mandigers CMPW, Diepersloot RJA, Dessens M, et al. A hospital outbreak of penicillin-resistant pneumococci in the Netherlands. Eur Respir J 1994; 7: 1635-9
31. Mandell LA. Antibiotics for pneumonia therapy. Med Clin North Am 1994 Sep; 78 (5): 997-1013
32. Goldstein EJC, Citron DM. Comparative in vitro inhibitory and killing activity of cefpirome, ceftazidime, and cefotaxime against Pseudomonas aeruginosa, enterococci, Staphylococcus epidermidis, and methicillin-susceptible and resistant and tolerant and non-tolerant Staphylococcus aureus. Antimicrob Agents Chemother 1985 Jul; 28 (1): 160-2
33. Foran RM, Brett JL, Wulf PH. Evaluating the cost impact of intravenous antibiotic dosing frequencies. DICP 1991; 25: 546-52
34. Choo U. UK revises indications for co-trimoxazole. Lancet 1995 Jul 15; 346: 175
35. Wiseman LR, Balfour JA. Ciprofloxacin: a review of its pharmacological profile and therapeutic use in the elderly. Drugs Aging 1994; 4 (2): 145-73
36. Peterson PK, Stein D, Guary DRP, et al. Prospective study of lower respiratory tract infections in an extended care nursing program: potential role of oral ciprofloxacin. Am J Med 1988 Sep; 65: 164-70
37. Pickering TD, Gurwitz JH, Zaleznik D, et al. The appropriateness of oral fluoroquinolone-prescribing in the long-term care selling. J Am Geriatr Soc 1994; 42: 28-32
38. Saltiel E, Weingarten S. Drug treatment of pneumonia in the elderly: efficacy and costs. Pharmacoeconomics 1993; 3 (4): 268-75
39. Wilson WR. Tolerance and safety of orally administered antimicrobial agents: an important factor in the selection of drug therapy. Curr Ther Res 1944; 55 Suppl. A: 49-56
40. Guay DRP. Sequential antimicrobial therapy: a realistic approach to cost containment. Pharmacoeconomics 1993; 3 (5): 341-4
41. Weingarten SR, Riedinger MS, Varis G, et al. Identification of low-risk hospitalized patients with pneumonia. Implications for early conversion to oral antimicrobial therapy. Chest 1994; 105: 1109-15
42. Ehrenkranz NJ, Nerenberg DE, Shultz JM, et al. Intervention to discontinue parenteral antimicrobial therapy in patients hospitalized wilh pulmonary infections: effect on shortening patient slay. Infect Control Hosp Epidemiol 1992; 13: 21-32
43. Hirta-Dulas CAI, Stein DJ, Guay DRP, et al. A randomized study of ciprofloxacin versus ceftriaxone in the treatment of nursing home acquired lower respiratory tract infections. J Am Geriatr Soc 1991; 39: 979-85
44. Ramirez JA, Srinath L, Ahkee S, et al. Early switch from intravenous to oral cephalosporins in treatment of hospitalized patients with community-acquired pneumonia. Arch Intern Med 1995, 155: 1273-6
45. Trenholme GM, Scmitt BA, Spear J, et al. Randomized study of intravenous/oral ciprofloxacin versus ceftazidime in the treatment of hospital and nursing home patients with lower respiratory tract infections. Am J Med 1989; 87 Suppl. 5A: 116S-8S
46. Dunagan WC, Woodward RS, Medoff G, et al. Antimicrobial misuse in patients with positive blood cultures. Am J Med 1989; 87: 253-9
47. Foster DA, Talsma A, Furumoto-Dawson A, et al. Influenza vaccine effectiveness in preventing hospitalization for pneumonia in the elderly. Am J Epidemiol 1992; 136: 296-307
48. Ortiz CR, LaForce FM. Prevention of community-acquired pneumonia. Med Clin North Am 1994 Sep; 78 (5): 1173-83
49. Gross PA, Hermogenes AW, Sacks HS, et al. The efficacy of influenza vaccine in elderly patients. Ann Intern Med 1995; 123: 518-27
50. Makela PH, Jokinen C, Pyhala R, et al. Use of vaccines for respiratory infections: strategies for influenzae and pneumococcal vaccines. Scand J Infect Dis 1990; Suppl. 70: 141-8
51. Fox RA. Treatment recommendations tor respiratory tract infections associated with aging. Drugs Aging 1993; 3 (1): 40-8
52. Anonymous. Appropriate treatment of pneumonia in the elderly may reduce costs. Drugs Ther Perspect 1993 Aug 30; 2 (4): 14-6
53. Butler JC, Breiman FR, Campbell JF, et al. Pneumococcal polysaccharide vaccine efficacy: an evaluation of current recommendations. JAMA 1993; 270: 1826-31
54. Nichol KL, Margolis KL, Wuorenma J, et al. The efficacy and cost effectiveness of vaccination against influenza among elderly persons living in the community. N Engl J Med 1994; 331: 778-84
55. Woo J, Ho SC, Mak YT, et al. Nutritional status of elderly patients during recovery from chest infection and the role of nutritional supplementation assessed by a prospective randomized single-blind trial. Age Ageing 1994; 23: 40-8
56. Hum C, Chakravorty NK, Annan G, et al. The clinical effects of vitamin C supplementation in elderly hospitalized patients with acute respiratory infections. Int J Vitam Nutr Res 1994; 64: 212-9
57. Nelson S, Summer W, Bogby G, et al. Granulocyte colony-stimulating factor enhances pulmonary host defences in normal and ethanol treated rats. J Infect Dis 1991; 164: 901-6
58. Lester P, Gentry M, Prehein L. Granulocyte colony-stimulating factor protects control rats but not ethanol-fed rats from fatal pneumococcal pneumonia. J Infect Dis 1993; 168: 922-6
59. Sperry S, Birdsall C. Outcomes of a pneumonia critical path. Nurs Econ 1994; 12: 332-45
60. Ester R, Bentz P, Sorensen M, et al. Patient-centred pneumonia care: a case management success story. Am J Nurs 1994; 94: 34-8
61. Rollins D, Thomasson C, Sperry B. Improving antibiotic delivery time to pneumonia patients: continuous quality improvement in action. J Nurs Care Qual 1994; 8: 22-31
62. May HM, Harrison TS, Harrison BDW. A criteria based audit of community-acquired pneumonia. Respir Med 1994; 88: 693-6
63. Jolley AE, Davies AJ, McLeod DT. Audit of the use of erythromycin in the treatment of community-acquired lower respiratory tract infections. Respir Med 1992; 86: 503-5
64. Dempsey CJ. Nursing home-acquired pneumonia: outcomes from a clinical process improvement program. Pharmacotherapy 1995; 15 (1 Pt 2): 33S-8S