Endocrine disorders and orthopedic problems in children

Current Opinion in Pediatrics

Volumn 8, Issue 1, 1996, Pages 68-70

  Mann, David C ^a  

^a University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MATURATION; BONE METABOLISM; BONE NECROSIS; CUSHING DISEASE; DISEASE ASSOCIATION; EPIPHYSIOLYSIS; FEMUR EPIPHYSIS; GROWTH HORMONE DEFICIENCY; HUMAN; HYPERCORTISOLISM; HYPERPARATHYROIDISM; HYPOTHYROIDISM; ORTHOPEDICS; OSTEOPOROSIS; PRIORITY JOURNAL; REVIEW;

ADRENOCORTICAL HYPERFUNCTION; BONE DISEASES; BONE DISEASES, METABOLIC; CHILD; ENDOCRINE SYSTEM DISEASES; EPIPHYSES, SLIPPED; GROWTH HORMONE; HUMANS; HYPOTHYROIDISM;

EID: 0029997540     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008480-199602000-00015     Document Type: Review

References (12)

1. Sanchez CP, Goodman WG, Brandli D, Goldenhersh M, Murray C, Carlton E, Hahn T, Salusky IB: Skeletal response to recombinant human growth hormone (rhGH) in children treated with long-term corticosteroids. J Bone Miner Res 1995, 10:2-6. Bone formation increased in children on long-term corticosteroids given rhGH. Optimal dosage and frequency still need to be determined.
2. Saggese G, Baroncelli GI, Bertelloni S, Cinquanta L, DiNero G: Effects of long-term treatment with growth hormone on bone and mineral metabolism in children with growth hormone deficiency. J Pediatr 1993, 122:37-45.
3. DeBoer H, Blok GJ, Van Lingen A, Teule GJJ, Lips P, Van der Veen EA: Consequences of childhood-onset growth hormone deficiency for adult bone mass. J Bone Miner Res 1994, 9:1319-1326. Bone mineral density measurements in men who had childhood-onset GHD revealed a moderate degree of osteopenia.
4. Saggese G, Cesaretti G, Barsanti S, Rossi A: Combination treatment with growth hormone and gonadotropin-releasing hormone analogs in short normal girls. J Pediatr 1995, 126:468-473. Combination treatment with growth hormone and gonadotropin-releasing hormone in short, endocrinologically normal girls may be useful in improving both height prognosis and predicted adult height.
5. Rosenfeld RG: Growth hormone therapy in Turner's syndrome: an update on final height Genentech National Cooperative Study Group. Acta Pediatr 1992, 383:3-6.
6. Bridges NA, Brook CGD: Progress report: growth hormone in skeletal dysplasia. Horm Res 1994, 42:231-234.
7. Williams BA, Morris LL, Toogood IRG, Penfold JL, Foster BK: Limb deformity and metaphyseal abnormalities in thalassaemia major. Am J Pediatr Hematol Oncol 1992, 14:197-201.
8. Roy DR: Perthes'-like changes caused by acquired hypothyroidism. Orthopedics 1991, 14:901-904.
9. Eberle AJ: Congenital hypothyroidism presenting as apparent spondyloepiphyseal dysplasia. Am J Med Genet 1993, 47:464-467.
10. Mann DC, Weddington J, Richton S: Hormonal studies in patients with slipped capital femoral epiphysis without evidence of endocrinopathy. J Pediatr Orthop 1988, 8:543-545.
11. Wells D, King JD, Roe TF, Kaufman FR: Review of slipped capital femoral epiphysis associated with endocrine disease. J Pediatr Orthop 1993, 13:610-614.
12. Loder RT, Wittenberg B, DeSilva G: Slipped capital femoral epiphysis associated with endocrine disorders. J Pediatr Orthop 1995, 15:349-356. Eighty-five patients with endocrine disorders and SCFE were reviewed. Hypothyroidism, GHD, and a variety of other endocrine isorders were associated with SCFE. All hypothyroid patients developed the first SCFE before or during hormonal supplementation; 92% with GHD developed the SCFE during or after supplementation.