Dynamic production of tumour necrosis factor-α (TNF-α) messenger RNA, intracellular and extracellular TNF-α by murine macrophages and possible association with protein tyrosine phosphorylation of STAT1α and ERK2 as an early signal

Immunology

Volumn 87, Issue 4, 1996, Pages 544-550

  Zheng, Z M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HERBIMYCIN A; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; BLOTTING, NORTHERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL CULTURE TECHNIQUES; DNA-BINDING PROTEINS; IMMUNOBLOTTING; INTERFERON-STIMULATED GENE FACTOR 3; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; KINETICS; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029997322     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.513591.x     Document Type: Article

References (3)

1. CARSWELL E.A., OLD L.J., KASSEL R.L., GREEN S., FIORE N. & WILLIAMSON B. (1975) An endotoxin-induced serum factor that causes necrosis of tumours. Proc Natl Acad Sci USA 72, 3666.
2. GIFFORD G.E., FLICK D.A., ABDALLAH N.A. & FISCH H. (1984) Production of a cytotoxin from phorbol myristate acetate- treated human promyelocytes. J Natl Cancer Inst 73, 69.
3. ABU-KHABAR K.S., ARMSTRONG J.A. & Ho M. (1992) Type I Interferon (IFN-α and β) suppress cytotoxin (tumour necrosis factor α and lymphotoxin) production by mitogen-stimulated human peritoneal blood mononuclear cells. J Leuk Biol 52, 165.