Does the cerebrospinal fluid protein concentration increase the risk of shunt complications?

British Journal of Neurosurgery

Volumn 10, Issue 3, 1996, Pages 267-274

  Brydon, H L ^a,c   Hayward, R ^a   Harkness, W ^a   Bayston, R ^b  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Cerebrospinal fluid protein; Cerebrospinal fluid shunts; Hydrocephalus; Shunt infection

Indexed keywords

PROTEIN;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; HYDROCEPHALUS; INFANT; MAJOR CLINICAL STUDY; MALE; NEWBORN; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; RISK ASSESSMENT; SHUNT INFECTION; SHUNTING;

EID: 0029996963     PISSN: 02688697     EISSN: None     Source Type: Journal    
DOI: 10.1080/02688699650040124     Document Type: Article

References (41)

1. Foltz EL, Shurtleff DB. Five year comparative study of hydrocephalus in children with and without operation (113 cases). J Neurosurg 1963;20:1064-78.
2. Occhipinti E, Carapella CM. Shunt failure in hydrocephalus with high protein fluid. Monog Neural Sci 1982;8:220-2.
3. Scarff TB, Anderson DE, Anderson CL, Caldwell CC. Complications of ventriculo-peritoneal shunts in premature infants. Concepts Pediat Neurosurg 1983;4:81-8.
4. Lorber J, Bhat US. Posthaemorrhagic hydrocephalus. Diagnosis, differential diagnosis, treatment and long-term results. Arch Dis Childh 1974;49,751-62.
5. Fouyas IP, Casey ATH, Thompson D, Harkness WF, Hayward RD. The use of intracranial pressure monitoring in the management of childhood hydrocephalus and shunt-related problems, Neurosurgery 1996;38: 726-32.
6. Luxton RW, Patel P, Keir G, Thompson EJ. A micromethod for measuring total protein in cerebrospinal fluid by using benzethonium chloride in microtitre plate wells. Clin Chem 1989;35:1731-4.
7. Jeppsson JO, Laurell CB, Franzén B. Agarose gel electrophoresis. Clin Chem 1979;25:629-38.
8. Riches PG, Michael D, Sheldon J, Weatherald L. Sensitive colloidal metal staining of cerebrospinal fluid proteins in agarose gels. Lab Practice 1986;35:10-12.
9. Laurell CB. Electroimmuno assay. Scand J Cli Lab Invest 1972;29,suppl. 124:21-37.
10. Brackenridge CJ. Cerebrospinal fluid protein fractions in health and disease. J Clin Pathol 1962;15:206-10.
11. Puca A, Anile C, Maria G, Rossi G. Cerebrospinal fluid shunting for hydrocephalus in the adult: factors related to shunt revision. Neurosurgery 1991;29:822-6.
12. Illingworth RD, Logue V, Symon L, Uemura K. The ventriculocaval shunt in the treatment of adult hydrocephalus. Results and complications in 101 patients. J Neurosurg 1971;35:681-5.
13. Saint-Rose C, Piatt JH, Renier D, Pierre-Kahn A, Hirsch JF, Hoffmann HJ, Humphreys RP, Hendrick EB. Mechanical complications in shunts. Pediatr Neurosurg 1991-2;17:2-9.
14. Pople IK, Quinn MW, Bayston R. Morbidity and outcome of shunted hydrocephalus. Zeitsch Kinderchir 1990;45,suppl. 1:29-31.
15. Pryce JD, PW Grant, Saul KJ. Normal concentrations of lactate, glucose, and protein in cerebrospinal fluid, and the diagnostic implications of abnormal concentrations. Clin Chem 1970;16:562-5.
16. Widell S. On the cerebrospinal fluid in normal children and in patients with acute abacterial meningo-encephalitis. Acta Paediatr 1958;47,suppl. 115:1-102.
17. Pezzotta S, Locatelli D, Bonfanti N, Sfogliarini R, Bruschi L, Rondini G. Shunt in high risk newborns. Childs Nerv Syst 1987;3:114-16.
18. Etienne J, Charpin B, Grando J, Brun Y, Bes M, Fleurette J. Characterisation of clinically significant isolates of Staphylococcus epidermidis from patients with cerebrospinal fluid shunt infections. Epidemiol Infect 1991;106:467-75.
19. D'Angio CT, McGowan KL, Baumgart S, St. Geme J, Harris MC. Surface colonisation with coagulase-negative staphylococci in premature neonates. J Pediatr 1989;114:1029-34.
20. Wise BL, Ballard R. Hydrocephalus secondary to intracranial hemorrhage in premature infants. Childs Brain 1976;2,234-41.
21. Hakim S, de la Roche FD, Burton JD. A critical analysis of valve shunts used in the treatment of hydrocephalus. Dev Med Child Neurol 1973;15:230-55.
22. Rayport MR, Reiss J. Hydrodynamic properties of certain shunt assemblies for the treatment of hydrocephalus. Part 1: Report of a case of communicating hydrocephalus with increased cerebrospinal fluid production treated by duplication of shunting device. Part 2: pressure-flow characteristics of the Spitz-Holter, Pudenz-Heyer and Cordis-Hakim shunt systems. J Neurosurg 1969;30:455-67.
23. Brydon HL, Bayston R, Hayward R, Harkness W. The effect of protein and blood cells on the flow-pressure characteristics of shunts. Neurosurgery 1996; 38:498-505.
24. Pudenz RH. CSF - protein study. PS Medical Corporation, Goleta, Medical Education Series Pamphlet 1992.
25. Trost HA, Heissler HE, Claussen G, Gabb MR. Testing the hydrocephalus shunt valve; long term bench test results of various new and explanted valves. The need for a model for testing valves under physiological conditions. Eur J Pediatr Surg 1991;1,suppl. 1:38-40.
26. Salmon JH. A ventriculoperitoneal shunt for hemorrhagic or high protein fluid. Surg Neurol, 8:69-70.
27. Schachter P, Findler G. Continuous spinal drainage of high viscosity CSF using IVAC system - technical note. Acta Neurochir (Wien) 1987:84:71-2.
28. Scarff JE. Treatment of hydrocephalus: an historical and critical review of methods and results. J Neurol Neurosurg Psychiatry 1963;26:1-26.
29. Macnab GH. The development of the knowledge and treatment of hydrocephalus. Dev Med Child Neurol 1968;8, suppl. 11:1-9
30. Brydon HL, Hayward R, Harkness W, Bayston R. Physical properties of cerebrospinal fluid of relevance to shunt function. 1: The effect of protein upon CSF viscosity. Br J Neurosurg 1995;9:639-44.
31. Brydon HL, Hayward R, Harkness W, Bayston R. Physical properties of cerebrospinal fluid of relevance to shunt function. 2: The effect of protein upon CSF surface tension and contact angle. Br J Neurosurg 1995;9:645-53.
32. Brydon HL, Hayward R, Harkness W, Bayston R. The effect of CSF proteins upon bacterial adhesion to shunt material. J Neurol Neurosurg Psychiatry 1994;57:391.
33. Pople IK, Bayston R, Hayward RD. Infection of cerebrospinal fluid shunts in infants - a study of aetiological factors. J Neurosurg 1992;77:29-36.
34. Overton MC, Snodgrass SR. Ventriculo-venous shunts for infantile hydrocephalus. A review of five years' experience with this method. J Neurosurg 1965;23:517-21.
35. Shanbhogue LRK, Paterson N. Effect of sepsis and surgery on trace minerals. J Parenteral Enteral Nutr 1990;14:287-9.
36. Towns ML, Bennett B, Check IJ, Hunter RL. An improved method for determining the microbial inhibitory activity of serum and its application to the study of patients with leukemia. Am J Clin Pathol 1989;92:192-8.
37. Verheecke P. On the τ-protein in cerebrospinal fluid. J Neurolog Sci 1975;26:277-81.
38. Eckstein HB. The surgical treatment of hydrocephalus with the Holter valve. Turkish J Pediat 1965;7:12-21.
39. Forrest DM, Cooper DGW. Complications of ventriculo-atrial shunts. A review of 455 cases. J Neurosurg 1968;29:506-12.
40. Thompson EJ. Immunochemistry of CSF proteins. In: Milford Ward A, Whicher JT (Eds) Immunochemistry in clinical laboratory medicine. Lancaster: MTP Press 1979;229-36.
41. Bayston R, Bannister C, Boston V, Burman R, Burns B, Cooke F, et al. A prospective randomised controlled trial of antimicrobial prophylaxis in hydrocephalus shunt surgery. Zeitsch Kinderchir 1990;45,suppl. 1:5-7.