Dehydroepiandrosterone does not prevent adrenocorticotrophin-induced hypertension in conscious rats

Clinical and Experimental Pharmacology and Physiology

Volumn 23, Issue 5, 1996, Pages 435-437

  Li, Ming ^a   Wen, Cheng ^a   Martin, Allison ^a   Whitworth, Judith A ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b ST GEORGE HOSPITAL   (Australia)

Author keywords

Adrenocorticotrophin; Dehydroepiandrosterone; Hypertension; Rat

Indexed keywords

CORTICOTROPIN; DEXAMETHASONE; PRASTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HYPERTENSION; MALE; NONHUMAN; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029996832     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1996.tb02755.x     Document Type: Article

References (11)

1. May M, Holems E, Rogers W, Poth M. Protection from glucocorticoid induced thymic involution by dehydroepiandrosterone. Life Sci. 1990; 46: 1627-31.
2. Shafagoj Y, Opoku J, Qureshi D, Regelson W, Kalimi M. Dehydroepiandrosterone prevents dexamethasone-induced hypertension in rats. Am. J. Physiol. 1992; 263: E210-13.
3. Haack D, Engel R, Vecsei P. The effect of chronic ACTH treatment on blood pressure and urinary excretion of steroids in the rat. Klin. Wochenschr. 1978; 56 (Suppl. 1): 183-6.
4. Whitworth JA, Hewitson TD, Li M et al. ACTH hypertension in the rat: Haemodynamic, metabolic and morphologic characteristics. J. Hypertens. 1990; 8: 27-36.
5. Kalimi M. Role of antiglucocorticoid RU 486 on dexamethasone-induced hypertension in rats. Am. J. Physiol. 1989; 256: E682-5.
6. Haack D, Mohring J, Mohring B, Petri M, Hackenthal E. Comparative study on development of corticosterone and DOCA hypertension in rats. Am. J. Physiol. 1977; 233: F403-11.
7. Freeman RH, Davis JO, Fullerton D. Chronic ACTH administration and the development of hypertension in rats. Proc. Soc. Exp. Biol. Med. 1980; 163: 473-7.
8. Spence CD, Coghlan JP, Denton DA, Mills EH, Whitworth JA, Scoggins BA. Adrenocortical steroid requirements for initiation of ACTH-dependent hypertension in sheep. Clin. Exp. Pharmacol. Physiol. 1989; 16: 759-72.
9. Whitworth JA, Saines D, Scoggins BA. Blood pressure and metabolic effects of cortisol and deoxycorticosterone in man. Clin. Exp. Hypertens. [A] 1984; 6: 795-809.
10. 3H]-DHEA binding in rat liver. Biochem. Biophys. Res. Commun. 1988; 156: 22-9.
11. Watlington CO, Kramer LB, Schuetz EG, Zilai J. Corticosterone 6β-hydroxylation correlates with blood pressure in spontaneously hypertensive rats. Am. J. Physiol. 1992; 262: F927-31.