Apolipoprotein B 3′ hypervariable repeat genotype: Association with plasma lipid concentration, coronary artery disease, and other restriction fragment polymorphisms

Clinical Chemistry

Volumn 42, Issue 6 SUPPL., 1996, Pages 927-932

  Wu, June Hsieh ^a   Chern, Ming Shyan ^b   Lo, Sing Kai ^a   Wen, Ming Shien ^b   Kao, Jau Tsuen ^c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Atherosclerosis; Cholesterol; DNA fingerprinting; Genetic polymorphism; Lipoproteins; Polymerase chain reaction; Race related differences; Restriction fragment length polymorphism; Stroke; Variable number tandem repeat

Indexed keywords

APOLIPOPROTEIN B;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENOTYPE; HUMAN; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; VARIABLE NUMBER OF TANDEM REPEAT;

ALLELES; APOLIPOPROTEINS B; CEREBROVASCULAR DISORDERS; CORONARY DISEASE; ELECTROPHORESIS, AGAR GEL; GENOTYPE; HUMANS; LIPIDS; MINISATELLITE REPEATS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 0029996534     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/42.6.927     Document Type: Article

References (28)

1. Yang CY, Gu ZW, Weng S, Kim TW, Chen SH, Pownall HJ, et al. Structure of apolipoprotein B-100 of human low density lipoprotein. Arteriosclerosis 1989;9:96-108.
2. Chan L, Vantuinen P, Ledbetter'DH, Daiger SP, Gotto AM Jr, Chen SH. The human apolipoprotein B100 gene: a highly polymorphic gene that maps to the short arm of chromosome 2. Biochem Biophys Res Commun 1985;133:248-55.
3. Demmer LA, Levin MS, Elovson J, Reuben MA, Lusis AJ, Gordon JI. Tissue-specific expression and developmental regulation of the rat apolipoprotein B gene. Proc Natl Acad Sci U S A 1986;83: 8102-6.
4. Knott TJ, Wallis SC, Pease RJ, Powell LM, Scott J. A hypervariable region 3′ to the human apolipoprotein B gene. Nucleic Acids Res 1986;14:9215-6.
5. Jeffreys AJ, Wilson V, Thein SL. Individual-specific "fingerprints" of human DNA. Nature 1985;316:76-9.
6. Huang LS, Breslow JL. A unique A-T rich hypervariable minisatellite 3′ to the apoB gene defines a high information restriction fragment length polymorphism. J Biol Chem 1987;212:8952-5.
7. Jenner K, Sidoli A, Ball M, Rodriguez JR, Pagani F, Giudici G, et al. Characterization of genetic markers in the 3′ end of the apoB gene and their use in family and population studies. Atherosclerosis 1988;69:39-49.
8. Friedl W, Ludwig EH, Paulweber B, Sandhofer F, McCarthy BJ. Hypervariability in a minisatellite 3′ of the apolipoprotein B gene in patients with coronary heart disease compared with normal control. J Lipid Res 1990;31:659-65.
9. Ludwig EH, Friedl W, McCarthy BJ. High-resolution analysis of a hypervariable region in the human apolipoprotein B gene. Am J Hum Genet 1989;45:458-64.
10. Ludwig EH, McCarthy BJ. Haplotype analysis of the human apolipoprotein B mutation associated with familial defective apolipoprotein B100. Am J Hum Genet 1990;47:712-20.
11. Bell GI, Selby MJ, Rutter WJ. The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences. Nature 1982;295:31-5.
12. Capon DJ, Chen EY, Levinson AD, Seeburg PH, Goeddel DV. Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature 1983;302: 33-7.
13. Krontiris TG, DiMartino NA, Colb M, Parkinson DR. Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumor DNA of cancer patients. Nature 1985;313:369-74.
14. Doodbourn SEY, Higgs DR, Clegg JB, Weatherall DJ. Molecular basis of length polymorphism in the human ζ-globulin gene complex. Proc Natl Acad Sci U S A 1983;80:5022-6.
15. Stoker NG, Cheah KSE, Griffin JR, Pope FM, Solomon E. A highly polymorphic region 3′ to the human type II collagen gene. Nucleic Acids Res 1985;13:4613-22.
16. Jeffrey AJ, Tamaki K, MacLeod A, Monckton DG, Neil DL, Armour JAL. Complex gene conversion events in germline mutation at human minisatellites. Nature Genet 1994;6:136-45.
17. Wu JH, Wen MS, Lo SK, Chern MS. Increased frequency of apolipoprotein B signal peptide sp24/24 in patients with coronary artery disease. General allele survey in the population of Taiwan and comparison with Caucasians. Clin Genet 1994;45:250-4.
18. Wu JH, Kao JT, Wen MS, Wu D. Coronary artery disease risk predicted by plasma concentrations of high-density lipoprotein cholesterol, apolipoprotein AI, apolipoprotein B, and lipoprotein(a) in a general Chinese population. Clin Chem 1993;39:209-12.
19. Wu JH, Wen MS, Lo SK, Wu D. DNA polymorphism of apolipoprotein B in the population of Taiwan. J Formos Med Assoo 1993; 92:330-5.
20. Boerwinkle E, Xiong W, Fourest E, Chan L. Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3′ hypervariable region. Proc Natl Acad Sci U S A 1989;86:212-6.
21. Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988;239:487-91.
22. Glantz SA. Primer of biostatistics, 3rd ed. New York: McGraw-Hill, 1992:144-8.
23. Rosner B. Fundamentals of biostatistics, 4th ed. Belmont, CA: Duxbury Press, 1995:383-6.
24. Hegele RA, Huang LS, Herbert PN, Blum CB, Buring JB, Hennekens JL, et al. Apolipoprotein B gene DNA polymorphism associated with myocardial infarction. N Engl J Med 1986;15: 1509-15.
25. Wu JH. Sequence of apolipoprotein B 3′ hypervariable repeat alleles. Gene 1995;159:235-8.
26. Martinson JJ, Boyce AJ, Clegg JB. VNTR alleles associated with the α-globin locus are haplotype and population related. Am J Hum Genet 1994;55:513-25.
27. Kunst CB, Warren ST. Cryptic and polar variation of the fragile X repeat could result in predisposing normal alleles. Cell 1994;77: 853-61.
28. Coresh J, Beaty TH, Kwiterovich PO Jr, Antonarakis SE. Pedigree and sib-pair linkage analysis suggest the apolipoprotein B gene is not the major gene influencing plasma apolipoprotein B levels. Am J Hum Genet 1992;50:1038-45.