Potentiation of excitatory amino acid-evoked adenosine release from rat cortex by inhibitors of adenosine kinase and adenosine deaminase and by acadesine

European Journal of Pharmacology

Volumn 303, Issue 1-2, 1996, Pages 27-38

  White, Thomas D ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Adenosine deaminase; Adenosine kinase; AICAR (AICA riboside, acadesine); AMPA ( amino 3 hydroxy 5 methyl 4 isoxasole propionic acid); Kainate; NMDA (N methyl D aspartate)

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; 5 IODOTUBERCIDIN; 5' AMINO 5' DEOXYADENOSINE; 9 (2 HYDROXY 3 NONYL)ADENINE; ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE KINASE; ADENOSINE KINASE INHIBITOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; EXCITATORY AMINO ACID; EXCITOTOXIN; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; PENTOSTATIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SLICE; CONTROLLED STUDY; DRUG POTENTIATION; MALE; METABOLISM; NERVE CELL DEGENERATION; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

EID: 0029996021     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00084-2     Document Type: Article

References (40)

1. Abbracchio, M.P. and F. Cattabeni, 1993, eds. Purines '92: pharmacology and clinical applications, Drug Dev. Res. 28, 195.
2. Ballarin, M., B.B. Fredholm, S. Ambrosio and N. Mahy, 1991, Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism, Acta Physiol. Scand. 142, 97, 1991.
3. Belardinelli, L. and A. Pelleg, eds., 1994, Adenosine and Adenine Nucleotides (Martinus Nijhoff, Boston, MA).
4. Chen, Y., D.I. Graham and T.W. Stone, 1992, Release of endogenous adenosine and its metabolites by the activation of NMDA receptors in the rat hippocampus in vivo, Br. J. Pharmacol. 106, 632.
5. Cottam, H.B., 1994, New adenosine kinase inhibitors with oral antiinflammatory activity, Drugs Future, 19, 485.
6. 3H]noradrenaline from rat cortical slices, Eur. J. Pharmacol. 197, 1.
7. Craig, C.G. and T.D. White, 1992, Low-level N-methyl-D-aspartate receptor activation provides a purinergic inhibitory threshold against further N-methyl-D-aspartate mediated neurotransmission, J. Pharmacol. Exp. Ther. 260, 278.
8. Craig, C.G. and T.D. White, 1993a, N-Methyl-D-aspartate- and non-N-methyl-D-aspartate-evoked adenosine release: distinct purinergic sources and mechanisms of release, J. Neurochem. 60, 1073.
9. Craig, C.G. and T.D. White, 1993b, NMDA-evoked adenosine release from rat cortex does not require the intermediate formation of nitric oxide, Neurosci. Lett. 158, 167.
10. Craig, C.G., S. Temple and T.D. White, 1994, Is cyclic AMP involved in excitatory amino acid-evoked adenosine release from cortical slices?, Eur. J. Pharmacol. Mol. Pharmacol. Sect. 269, 79.
11. Dolphin, A.C. and E.R. Archer, 1983, An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus, Neurosci. Lett. 43, 49.
12. Dragunow, M., 1991, Adenosine and epileptic seizures, in: Adenosine and Adenine Nucleotides as Regulators of Cellular Function, ed. J.W. Phillis (CRC, Boca Raton, FL) p. 367.
13. Dragunow, M. and H.A. Robertson, 1987, 8-Cyclopentyl-1,3-dimethyl-xanthine prolongs epileptic seizures in rats, Brain Res. 417, 377.
14. 3H]D-aspartate release from cerebellar granule cells, Neurochem. Int. 11, 77.
15. Firestein, G.S., D.A. Bullough, M.D. Erion, R. Jiminez, M. Ramirez-Weinhouse, J. Barankiewicz, C.W. Smith, H.E. Gruber and K.M. Mullane, 1995, Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor, J. Immunol. 154, 326.
16. Gruber, H.E., M.E. Hoffer, D.R. McAllister, P.K. Laikind, T.A. Lane, G.W. Schmid-Schonbein and R.L. Engler, 1989, Increased adenosine concentration in blood from ischemic myocardium by acadesine: effects on flow, granulocytes, and injury, Circulation 80, 1400.
17. +- and glutamate-evoked release of endogenous adenosine from rat cortical slices, J. Neurochem. 54, 256.
18. Hoehn, K. and T.D. White, 1990b, N-Methyl-D-aspartate, kainate and quisqualate release endogenous adenosine from rat cortical slices, Neuroscience 39, 441.
19. 3H]norepinephrine from rat cortical slices, J. Pharmacol. Exp. Ther. 255, 174.
20. Jonzon, B. and B.B. Fredholm, 1985, Release of purines, noradrenaline, and GABA from rat hippocampal slices by field stimulation, J. Neurochem. 44, 217.
21. Kroll, K., U.K.M. Decking, K. Dreikorn and J. Schrader, 1993, Rapid turnover of the AMP-adenosine metabolic cycle in the guinea pig heart, Circ. Res. 73, 846.
22. Lipton, S.S. and P.A. Rosenberg, 1994, Mechanisms of disease: excitatory amino acids as a final common pathway for neurological disorders. New Engl. J. Med. 330, 613.
23. Lloyd, H.G.E. and B.B. Fredholm, 1995, Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices, Neurochem. Int. 26, 387.
24. Manzoni, O.J., T. Manabe and R.A. Nicoll, 1994, Release of adenosine by activation of NMDA receptors in the hippocampus, Science 265, 2098.
25. Mitchell, J.B., C.R. Lupica and T.V. Dunwiddie, 1993, Activity-dependent release of endogenous adenosine modulates synaptic responses in the rat hippocampus, J. Neurosci. 13, 3439.
26. Mullane, K., 1993, Acadesine: the prototype adenosine regulating agent for reducing myocardial ischaemic injury, Cardiovasc. Res. 27, 43.
27. Mullane, K. and M. Young, 1993, Acadesine: prototype adenosine regulating agent for treating myocardial ischemia-reperfusion injury, Drug Dev. Res. 28, 336.
28. Pak, M.A., H.L. Haas, U.K.L. Decking and J. Schrader, 1994, Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices, Neuropharmacology 33, 1049.
29. Pazzagli, M., C. Corsi, S. Latini, F. Pedata and G. Pepeu, 1994, In vivo regulation of extracellular adenosine levels in the cerebral cortex by NMDA and muscarinic receptors, Eur. J. Pharmacol. 254, 277.
30. Sciotti, V.M. and D.G.L. Van Wylen, 1993, Increases in interstitial adenosine and cerbral blood flow with inhibition of adenosine kinase and adenosine deaminase, J. Cerebral Blood Flow Metab. 13, 201.
31. Sciotti, V.M., F.M. Roche, M.C. Grabb and D.G.L. Van Wylen, 1992, Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia, J. Cerebral Blood Flow Metab. 12, 646.
32. Sciotti, V.M., T.S. Park, R.M. Berne and D.G.L. Van Wylen, 1993, Changes in extracellular adenosine during chemical or electrical brain stimulation, Brain Res. 613, 16.
33. Smolenski, R.T., Z. Kochan, R. McDouall, C. Page, A.-M.L. Seymour and M.H. Yacoub, 1994, Endothelial nucleotide catabolism and adenosine production, Cardiovasc. Res. 28, 100.
34. Teitelbaum, J.S., R.J. Zatorre, S. Carpenter, D. Gendron, A.C. Evans, A. Gjedde and N.R. Cashman, 1990, Neurological sequelae of domoic acid intoxication due to the ingestion of contaminated mussels, New Engl. J. Med. 322, 1781.
35. 6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice, Eur. J. Pharmacol. 249, 265.
36. White, T.D., 1994a, Pharmacological augmentation of excitatory amino acid-evoked adenosine release from rat cortical slices, Drug Dev. Res. 31, 333.
37. White, T.D., 1994b, Manipulation of excitatory amino acid-evoked release of adenosine from rat cortical slices, Soc. Neurosci. Abstr. 20, 732.
38. Young, D. and M. Dragunow, 1994, Status epilepticus may be caused by loss of adenosine anticonvulsant mechanisms. Neuroscience 58, 245.
39. Zhang, G., P.H. Franklin and T.F. Murray, 1993, Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility, J. Pharmacol. Exp. Ther. 264, 1415.
40. Zhu, P.J. and K. Krnjevic, 1994, Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions, Neuroscience 63, 489.