-
2
-
-
0028068862
-
Clinical studies of irinotecan alone and in combination with cisplatin
-
Fukuoka M, Masuda N. Clinical studies of irinotecan alone and in combination with cisplatin. Cancer Chemother Pharmacol 1994; 34: S105-11.
-
(1994)
Cancer Chemother Pharmacol
, vol.34
-
-
Fukuoka, M.1
Masuda, N.2
-
3
-
-
0023225704
-
Recent studies of DNA topoisomerases
-
Wang JC. Recent studies of DNA topoisomerases. Biochim Biophys Acta 1987; 909: 1-9.
-
(1987)
Biochim Biophys Acta
, vol.909
, pp. 1-9
-
-
Wang, J.C.1
-
4
-
-
0017708066
-
Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA
-
Champoux JJ. Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA. Proc Natl Acad Sci USA 1977; 74: 3800-4.
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, pp. 3800-3804
-
-
Champoux, J.J.1
-
5
-
-
0023236920
-
Topoisomerase II as a target of anticancer drug action in mammalian cells
-
Kohn KW, Pommier Y, Kerrigan D, et al. Topoisomerase II as a target of anticancer drug action in mammalian cells. NCI Monogr 1987; 4: 61-71.
-
(1987)
NCI Monogr
, vol.4
, pp. 61-71
-
-
Kohn, K.W.1
Pommier, Y.2
Kerrigan, D.3
-
7
-
-
10544255910
-
Discovery and design of topoisomerase I inhibitors
-
Johnson RK, Hertzberg RP, Eng W-K, McCabe FL, Kingsbury WD, Hecht SM. Discovery and design of topoisomerase I inhibitors. Proc Am Cancer Ass 1992; 33: 593-4.
-
(1992)
Proc Am Cancer Ass
, vol.33
, pp. 593-594
-
-
Johnson, R.K.1
Hertzberg, R.P.2
Eng, W.-K.3
McCabe, F.L.4
Kingsbury, W.D.5
Hecht, S.M.6
-
8
-
-
0025762137
-
Wakayin: A novel pyrroloiminoquinone from the ascidian Clavelina sp
-
Copp BR, Ireland CM, Barrows LR. Wakayin: a novel pyrroloiminoquinone from the ascidian Clavelina sp. J Org Chem 1991; 56: 4596-7.
-
(1991)
J Org Chem
, vol.56
, pp. 4596-4597
-
-
Copp, B.R.1
Ireland, C.M.2
Barrows, L.R.3
-
9
-
-
0027167775
-
Novel Cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya
-
Radisky DC, Radisky ES, Barrows LR, Copp BR, Kramer RA, Ireland CM. Novel Cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya. J Am Cancer Soc 1993; 115: 1632-7.
-
(1993)
J Am Cancer Soc
, vol.115
, pp. 1632-1637
-
-
Radisky, D.C.1
Radisky, E.S.2
Barrows, L.R.3
Copp, B.R.4
Kramer, R.A.5
Ireland, C.M.6
-
10
-
-
0027366526
-
Makaluvamines, marine natural products, are active anti-cancer agents and DNA Topo II inhibitors
-
Barrows LR, Radisky DC, Copp BR, et al. Makaluvamines, marine natural products, are active anti-cancer agents and DNA Topo II inhibitors. Anti-Cancer Drug Des 1993; 8: 333-47.
-
(1993)
Anti-Cancer Drug des
, vol.8
, pp. 333-347
-
-
Barrows, L.R.1
Radisky, D.C.2
Copp, B.R.3
-
11
-
-
0027942883
-
Inhibition of topoisomerase II-mediated DNA cleavage by pyridoacridine alkaloids from a Cystodytes sp. ascidian: A mechanism for the apparent intercalator-induced inhibition of topoisomerase II
-
McDonald LA, Eldredge GS, Barrows LR, Ireland CM. Inhibition of topoisomerase II-mediated DNA cleavage by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II. J Med Chem 1994; 37: 3819-27.
-
(1994)
J Med Chem
, vol.37
, pp. 3819-3827
-
-
McDonald, L.A.1
Eldredge, G.S.2
Barrows, L.R.3
Ireland, C.M.4
-
13
-
-
0028012558
-
A rapid mechanism-based screen to detect potential anti-cancer agents
-
Swaffar DS, Ireland CM, Barrows LR. A rapid mechanism-based screen to detect potential anti-cancer agents. Anti-Cancer Drugs 1994, 5: 15-23
-
(1994)
Anti-Cancer Drugs
, vol.5
, pp. 15-23
-
-
Swaffar, D.S.1
Ireland, C.M.2
Barrows, L.R.3
-
14
-
-
0022656381
-
DNA damage by antitumor acridines is mediated by mammalian DNA topoisomerase II
-
Rowe TC, Chen GL, Hsiang Y-H, Liu LF. DNA damage by antitumor acridines is mediated by mammalian DNA topoisomerase II. Cancer Res 1986; 46: 2021-6.
-
(1986)
Cancer Res
, vol.46
, pp. 2021-2026
-
-
Rowe, T.C.1
Chen, G.L.2
Hsiang, Y.-H.3
Liu, L.F.4
-
15
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang Y-H, Hertzberg RP, Hecht S, Liu LF. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 1985; 260: 14873-8.
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.-H.1
Hertzberg, R.P.2
Hecht, S.3
Liu, L.F.4
-
16
-
-
0021760306
-
Nucleoside sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV 40 DNA
-
Been MD, Burgess RR, Champoux JJ. Nucleoside sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV 40 DNA. Nucleic Acids Res 1984; 12: 3097-114.
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 3097-3114
-
-
Been, M.D.1
Burgess, R.R.2
Champoux, J.J.3
-
17
-
-
0024273504
-
Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin
-
Jaxel C, Kohn KW, Pommier Y Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin. Nucleic Acids Res 1988; 16: 11157-71.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 11157-11171
-
-
Jaxel, C.1
Kohn, K.W.2
Pommier, Y.3
-
18
-
-
0024324205
-
On the mechanism of topoisomerase I inhibition by camptothecin: Evidence for binding to an enzyme-DNA complex
-
Hertzberg RP, Caranfa MJ, Hecht SM. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry 1989; 28: 4629-38.
-
(1989)
Biochemistry
, vol.28
, pp. 4629-4638
-
-
Hertzberg, R.P.1
Caranfa, M.J.2
Hecht, S.M.3
-
19
-
-
0024548388
-
The effects of camptothecin on the reaction and the specificity of the wheat germ type I topoisomerase
-
Champoux JJ, Aronoff R. The effects of camptothecin on the reaction and the specificity of the wheat germ type I topoisomerase. J Biol Chem 1989; 264: 1010-5.
-
(1989)
J Biol Chem
, vol.264
, pp. 1010-1015
-
-
Champoux, J.J.1
Aronoff, R.2
-
20
-
-
0025037336
-
Irreversible trapping of the DNA-topoisomerase I covalent complex
-
Hertzberg RP, Busby RW, Caranfa MJ, et al. Irreversible trapping of the DNA-topoisomerase I covalent complex. J Biol Chem 1990; 265: 19287-95.
-
(1990)
J Biol Chem
, vol.265
, pp. 19287-19295
-
-
Hertzberg, R.P.1
Busby, R.W.2
Caranfa, M.J.3
-
21
-
-
0027202339
-
DNA minor groove-binding ligands: A different class of mammalian DNA topoisomerase I inhibitors
-
Chen AY, Yu C, Gatto B, Liu LF. DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors. Proc Natl Acad Sci USA 1993; 90: 8131-5.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8131-8135
-
-
Chen, A.Y.1
Yu, C.2
Gatto, B.3
Liu, L.F.4
-
22
-
-
0027369170
-
The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerase I and II
-
Larsen AK, Grondard L, Couprie J. et al. The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerase I and II. Biochem Pharmacol 1993; 46: 1403-12.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 1403-1412
-
-
Larsen, A.K.1
Grondard, L.2
Couprie, J.3
-
23
-
-
0027375881
-
Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: Correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential
-
Elsea SH, McGuirk PR, Gootz P, Moynihan M, Osheroff N. Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential. Antimicrob Agents Chemother 1993; 37: 2599-605.
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 2599-2605
-
-
Elsea, S.H.1
McGuirk, P.R.2
Gootz, P.3
Moynihan, M.4
Osheroff, N.5
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