Expression of keratinocyte growth factor in embryonic liver of transgenic mice causes changes in epithelial growth and differentiation resulting in polycystic kidneys and other organ malformations

Oncogene

Volumn 12, Issue 10, 1996, Pages 2109-2119

  Nguyen, Hung Q ^a   Danilenko, Dimitry M ^a   Bucay, Nathan ^a   DeRose, Margaret L ^a   Van, Gwyneth Y ^a   Thomason, Arlen ^a   Simonet, W Scott ^a  

^a AMGEN INC   (United States)

Author keywords

Keratinocyte growth factor; Mesenchymal epithelial interactions; Polycystic kidney; Transgenic mice

Indexed keywords

APOLIPOPROTEIN E; GROWTH FACTOR RECEPTOR; INSULIN; KERATINOCYTE GROWTH FACTOR;

ANIMAL EXPERIMENT; ARTICLE; BILE DUCT; BRONCHIOLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; EPITHELIUM CELL; FEMALE; HAIR FOLLICLE; HYPERKERATOSIS; HYPERPLASIA; INTESTINE EPITHELIUM; KIDNEY COLLECTING TUBULE; KIDNEY POLYCYSTIC DISEASE; LIVER; LIVER CELL; LIVER HYPERTROPHY; LUNG ALVEOLUS CELL; MOUSE; NONHUMAN; PANCREAS ISLET CELL HYPERPLASIA; PAPILLOMATOSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECOMBINANT GENE; TRANSGENIC MOUSE; UROTHELIUM;

ABNORMALITIES; ANIMALS; APOLIPOPROTEINS E; CELL DIFFERENTIATION; CELL DIVISION; EPITHELIAL CELLS; EPITHELIUM; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 7; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION; GROWTH SUBSTANCES; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LUNG; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; POLYCYSTIC KIDNEY DISEASES; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; TRANSGENES;

ANIMALIA; MUS MUSCULUS;

EID: 0029995613     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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