A high affinity T cell receptor?

Immunology and Cell Biology

Volumn 74, Issue 3, 1996, Pages 292-297

  Alberti, S ^a,b  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b Consorzio Mario Negri Sud ^*  (Italy)

Author keywords

alloreactivity; binding affinity; T cell receptor; T cell recognition

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ALLOIMMUNITY; BINDING AFFINITY; HUMAN; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; RECEPTOR AFFINITY; REVIEW; T LYMPHOCYTE;

EID: 0029995416     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1038/icb.1996.51     Document Type: Review

References (38)

1. Williams AF, Beyers AD. At grips with interactions. Nature 1992; 356: 746-7.
2. Schneck J, Maloy WL, Coligan JE, Margulies DH. Inhibition of an allospecific T cell hybridoma by soluble class I proteins and peptides: estimation of the affinity of a T cell receptor for MHC. Cell 1989; 56: 47-55.
3. Corr M, Slanetz AE, Boyd LF et al. T cell receptor-MHC class I peptide interactions: affinity, kinetics and specificity. Science 1994; 265: 946-9.
4. Matsui K, Boniface JJ, Reay PA, Schild H, Fazekas de St. Groth B, Davis MM. Low affinity interaction of peptide-MHC complexes with T cell receptors. Science 1992; 254: 1788-90.
5. k complexes: Correlation of the dissociation rate with T-cell responsiveness. Proc. Natl Acad. Sci. USA 1994; 91: 12 862-6.
6. Weber S, Traunecker A, Oliveri F, Gerhard W, Karjalainen K. Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor. Nature 1992; 356: 793-6.
7. Sykulev Y, Brunmark A, Tsomides TJ et al. High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc. Natl Acad. Sci. USA 1994; 91: 11 487-91.
8. Davies DR, Padlan EA, Sheriff S. Antibody-antigen complexes. Annu. Rev. Biochem. 1990; 59: 439-73.
9. Ashton-Rickardt PG, Tonegawa S. A differential-avidity model for T-cell selection. Immunol. Today 1994; 15: 362-6.
10. Von Boehmer H. Positive selection of lymphocytes. Cell 1994; 76: 219-28.
11. Nossal GJV. Negative selection of lymphocytes. Cell 1994; 76: 229-39.
12. Sprent J, Webb SR. Intrathymic and extrathymic clonal deletion of T cells. Curr. Opin. Immunol. 1995; 7: 196-205.
13. Karjalainen K. High sensitivity, low affinity-paradox of T-cell receptor recognition. Curr. Opin. Immunol. 1994; 6: 9-12.
14. Janeway Jr CA. Ligands for the T-cell receptor: Hard times for avidity models. Immunol. Today 1995; 16: 223-5.
15. Alexander-Miller MA, Burke K, Koszinowski UH, Hansen TH, Connolly JM. Alloreactive cytotoxic T lymphocytes generated in the presence of viral-derived peptides show exquisite peptide and MHC specificity. J. Immunol. 1993; 151: 1-10.
16. Sette A, Vitiello A, Reherman B et al. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. J. Immunol. 1994; 153: 5586-92.
17. Rötzschke O, Falck K, Faath S, Rammensee H-G. On the nature of peptides involved in T cell alloreactivity. J. Exp. Med. 1991; 174: 1059-1070.
18. + T cell recognition of class II MHC molecules. J. Immunol 1995; 154: 5153-64.
19. De Magistris MT, Alexander J, Coggeshall M et al. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 1992; 68: 625-34.
20. Allen PM. Peptides in positive and negative selection: A delicate balance. Cell 1994; 76: 593-6.
21. Alexander J, Snoke K, Ruppert J et al. Functional consequences of engagement of the T cell receptor by low affinity ligands. J. Immunol. 1993; 150: 1-7.
22. Symer DE, Dintzis RZ, Diamond DJ, Dintzis HM. Inhibition or activation of human T cell receptor transfectants is controlled by defined, soluble antigen arrays. J. Exp. Med. 1992; 176: 1421-30.
23. Hunt DF, Henderson RA, Shabanowitz J et al. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 1992; 255: 1261-3.
24. Chicz RM, Urban RG, Gorga JC, Vignali DAA, Lane WS, Strominger JL. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. Exp. Med. 1993; 178: 27-47.
25. Kageyama S, Tsomides TJ, Sykukev Y, Eisen HN. Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J Immunol. 1995; 154: 567-76.
26. Valitutti S, Müller S, Cella M, Padovan E, Lanzavecchia A. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 1995; 375: 148-51.
27. Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994; 76: 263-74.
28. Takahama Y, Suzuki H, Katz KS, Grusby MJ, Singer A. Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC. Nature 1994; 371: 67-9.
29. Bentley GA, Boulot G, Karjalainen K, Mariuzza RA. Crystal structure of the β chain of a T cell antigen receptor. Science 1995; 267: 1984-7.
30. Katayama CD, Eidelman FJ, Duncan A, Hooshmand F, Hedrick SM. Predicted complementarity determining regions of the T cell antigen receptor determine antigen specificity. EMBO J. 1995; 14: 927-38.
31. Jorgensen JL, Esser U, Fazekas de St. Groth B, Reay PA, Davis MM. Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 1992; 355: 224-30.
32. Patten PA, Rock EP, Sonoda T, Fazekas de St. Groth B, Jorgensen JL, Davis MM. Transfer of putative complementarity-determining region loops of T cell receptor V domains confers toxin reactivity but not peptide/MHC specificity. J. Immunol. 1993; 150: 2281-94.
33. Bjorkman PJ, Saper MA, Samraoui B, Benntt WS, Strominger JL, Wiley DC. Structure of the human class I histocompatibility antigen, HLA-A2. Nature 1987; 329: 506-12.
34. Stern LJ, Brown JH, Jardetzky TS et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994; 368: 215-21.
35. Sherman LA, Chattopadhyay S, Biggs JA, Dick II RF, Bluestone JA. Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptides. Proc. Natl Acad. Sci. USA 1993; 90: 6949-51.
36. Murphy DB, Lo D, Rath S et al. A novel MHC class II epitope expressed in thymic medulla but not cortex. Nature 1989; 338: 765-8.
37. Maier CC, Galin FS, Jarpe MA et al. A Vλx-bearing monoclonal antibody with similar specificity and sequence to encephalitogenic T cell receptors. J. Immunol. 1994; 153: 1132-9.
38. Zheng B, Xue W, Garnett K. Locus-specific somatic hypermutation in germinal centre T cells. Nature 1994; 372: 556-9.