Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3β-(4-[125I]iodophenyl) tropan-2β-carboxylic acid isopropyl ester ([125I]RTI-121)

Nuclear Medicine and Biology

Volumn 23, Issue 3, 1996, Pages 277-284

  Lever, John R ^a   Scheffel, Ursula ^a   Stathis, Marigo ^a   Seltzman, Herbert H ^b   Wyrick, Christopher D ^b   Abraham, Philip ^b   Parham, Karol ^b   Thomas, Brian F ^b   Boja, John W ^c   Kuhar, Michael J ^c   Carroll, F Ivy ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b RTI INTERNATIONAL   (United States)

^c NIDA Addiction Research Center   (United States)

Author keywords

Amphetamine; Dopamine transporter; Metabolism; Radioiodine; Radiotracer; RTI 121

Indexed keywords

3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID ISOPROPYL ESTER; DESIPRAMINE; DEXAMPHETAMINE; HALOPERIDOL; IODINE 125; KETANSERIN; PAROXETINE; PRAZOSIN; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MOUSE;

AMPHETAMINE; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CARRIER PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; IODINE RADIOISOTOPES; ISOTOPE LABELING; KINETICS; LIGANDS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; TISSUE DISTRIBUTION;

EID: 0029995415     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/0969-8051(95)02074-8     Document Type: Article

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