Naphthylisoquinoline alkaloids exhibit strong growth-inhibiting activities against Plasmodium falciparum and P. berghei in vitro -Structure-activity relationships of dioncophylline C

Annals of Tropical Medicine and Parasitology

Volumn 90, Issue 2, 1996, Pages 115-123

  Francois G ^a  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

5 O DEMETHYL 8 O METHYL 7 EPIDIONCOPHYLLINE A; DIONCOLACTONE A; DIONCOPHYLLINE A; DIONCOPHYLLINE C; ISOQUINOLINE ALKALOID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANIMALS; ANTIMALARIALS; CELLS, CULTURED; HUMANS; ISOQUINOLINES; MICE; NAPHTHOLS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 0029995062     PISSN: 00034983     EISSN: None     Source Type: Journal    
DOI: 10.1080/00034983.1996.11813035     Document Type: Article

References (6)

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2. BJÖRKMAN, A. & PHILLIPS-HOWARD, P. A. (1990). The epidemiology of drug-resistant malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84, 177-180.
3. BRINGMANN, G. (1986). The naphthylisoquinoline alkaloids. In The Alkaloids, Vol. 29, ed. Brossi, A., pp. 141-184. New York: Academic Press.
4. BRINGMANN, G., LISCH, D., REUSCHER, H., AKÉ ASSI, L. & GÜNTHER, K. (1991d). Atrop-diastercomer separation by racemate resolution techniques: N-methyl-dioncophylline A and its 7-epimer from Ancistrocladus abbrerialus. Phytochemistry, 30, 1307-1310.
5. BRINGMANN, G., ORTMANN, T., RÜBENACKER, M. & AKÉ ASSI, L. (1991c). An unusual 4-methoxylated naphthylisoquinoline alkaloid from the leaves of Triphyophyllum peltatum. Planta Medica, 57 (Suppl. 2), 96.
6. BRINGMANN, G., ORTMANN, T., ZAGST, R., SCHÖNER, B., AKÉ ASSI, L. & BURSCHKA, C. (1992a). ( ±)-Dioncophyllacine A, a naphthylisoquinoline alkaloid with a 4-methoxy substituent from the leaves of Triphyophyllum peltatum. Phytochemistry, 31, 4015-4018.