Production of tissue-type plasminogen activator (t-PA) and type-1 plasminogen activator inhibitor (PAI-1) in mildly cirrhotic rat liver

Thrombosis and Haemostasis

Volumn 75, Issue 5, 1996, Pages 801-807

  Seki, Taiichiro ^a,c   Imai, Hideo ^b   Uno, Shigeyuki ^a   Ariga, Toyohiko ^a   Gelehrter, Thomas D ^c  

^a NIHON UNIVERSITY   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON TETRACHLORIDE; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; RNA; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LIVER CIRRHOSIS; LIVER FAILURE; LIVER REGENERATION; MALE; NONHUMAN; NORTHERN BLOTTING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

EID: 0029994406     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1650370     Document Type: Article

References (56)

1. Mayer M. Biomedical and biochemical aspects of the plasminogen activation system. Clin Biochem 1990; 23: 197-211.
2. Danø K, Andreasen PA, Grondahl-Hansen J, Kristensen P, Nielsen LS, Skriver L. Plasminogen activators, tissue degradation and cancer. Adv Cancer Res 1985; 44: 139-266.
3. Andreasen PA, Georg B, Lund LR, Riccio A, Stacey SN. Plasminogen activator inhibitors: hormonally regulated serpins. Mol Cell Endocrinol 1990; 68: 1-19.
4. Heaton JH, Kathju S, Gelehrter TD. Transcriptional and posttranscriptional regulation of type 1 plasminogen activator inhibitor and tissue-type plasminogen activator gene expression in HTC rat hepatoma cells by glucocorticoids and cyclic nucleotides. Mol Endocrinel 1992; 6: 53-60.
5. Healy AM, Gelehrter TD. Induction of plasminogen activator inhibitor-1 in Hep G2 human hepatoma cells by mediators of the acute phase response. J Biol Chem 1994; 269: 19095-100.
6. Quax PHA, van den Hoogen CM, Verheijen JH, Padro T, Zeheb R,Gelehrter TD, van Berkel TJC, Kuiper J, Emeis JJ. Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type-1 mRNA in rat tissue in vivo. J Biol Chem 1990; 265: 15560-3.
7. Astrup T. Tissue activators of plasminogen. Fed Proc 1969; 25: 42-51.
8. Oshiba S, Ariga T. Purification and characterization of the biliary plasminogen activator, bilokinase. J Biol Chem 1983; 258: 622-8.
9. Ariga T, Oshiba S, Seki T, Imai H, Imai S, Sawai H. Studies on bilokinase, a biliary plasminogen activator: immunologic property and organ distribution. Thromb Res 1989; 56:37-48.
10. Seki T, Ariga T, Saito K, Sugawara T, Oshiba S. Hormonal regulation of plasminogen activator production by rat hepatocytes in primary culture. Thromb Res 1990; 58: 543-54.
11. Seki T, Watanabe K, Saito K, Ariga T. Purification and characterization of hepatic plasminogen activator (h-PA) in the conditioned medium of rat hepatocytes in primary culture. Biosci Biotech Biochem 1993; 57: 1369-71.
12. Heaton JH, Nebes VL, O'Dell LG, Morris SM, Gelehrter TD. Glucocorticoid and cyclic nucleotide regulation of plasminogen activator and plasminogen activator inhibitor gene expression in primary cultures of rat hepatocytes. Mol Endocrinol 1989; 3: 185-92.
13. Heaton JH, Gelehrter TD. Glucocorticoid induction of plasminogen activator and plasminogen activator-inhibitor messenger RNA in rat hepatoma cells. Mol Endocrinol 1989; 3: 349-55.
14. Heaton JH, Gelehrter TD. Cyclic nucleotide regulation of plasminogen activator and plasminogen activator-inhibitor messenger RNAs in rat hepatoma cells. Mol Endocrinol 1990; 4: 171-8.
15. Thornton AJ, Bruzdzinski CJ, Raper SE, Gelehrter TD. Plasminogen activator inhibitor-1 is an immediate early response gene in regenerating rat liver. Cancer Res 1994; 54: 1337-43.
16. Konkle BA, Schuster SJ, Kelly MD, Harjes K, Hassett DE, Bohrer M, Tavassoli M. Plasminogen activator inhibitor-1 messenger RNA expression is induced in rat hepatocytes in vivo by dexamethasone. Blood 1992; 79: 2636-47.
17. Podor T, Hirsh JJ, Gelehrter TD, Zeheb R, Torry D, Guigoz Y, Sierra F, Gauldie J. Type 1 plasminogen activator is not an acute phase reactant in rats. Lack of IL-6 and hepatocyte-dependent synthesis. J Immunol 1993; 150: 225-35.
18. Lasierra J, Aza MJ, Vilades E, poblet S, Barrao F, Bayon E, Gonzalez J. Tissue plasminogen activator and plasminogen activator inhibitor in patients with liver cirrhosis. Fibrinolysis 1991; 5: 117-20.
19. Ferro D, Quintarelli CQ, Saliola M, Alessandri C, Basili S, Bonavita MS, Violi F. Prevalence of hyperfibrinolysis in patients with liver cirrhosis. Fibrinolysis 1993; 7: 59-62.
20. Kirchheimer JC, Huber K, Polterauer P, Binder BR. Urokinase antigen in plasma of patients with liver cirrhosis and hepatoma. Thromb Haemost 1985; 54: 617-8.
21. Leiper K, Croll A, Booth NA, Moore NR, Sinclair T, Bennett B. Tissue plasminogen activator, plasminogen activator inhibitors and activator-inhibitor complex in liver disease. J Clin Pathol 1994; 47: 214-7.
22. Oshiba S, Imai H, Sawai H, Imai S, Takao K, Suzuki H, Ariga T. Hepatobiliary fibrinolysis in experimental liver cirrhosis. Nihon Univ J Med 1990; 32: 355-63.
23. McLean KE, McLean AEM, Sutton PM. Instant cirrhosis: An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone. Br J Exp Path 1969; 50: 502-6.
24. Koneff AA. Adaptation of the Mallory-Azan staining methods to the anterior pituitary of the rat. Stain Technol 1938; 13: 49-52.
25. Schneider WC. Phosphorus compounds in animal tissue. I. Extraction and estimation of deoxypentose nucleic acid and of pentose nucleic acid. J Biol Chem 1945; 161: 293-303.
26. Burton K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J 1995; 62: 315-23.
27. Zeheb R, Rafferty UM, Rodriguez MA, Andreasen P, Gelehrter TD. Immunoaffinity purification of HTC rat hepatoma cell plasminogen activator-inhibitor-1. Thromb Haemost 1987; 58: 1017-23.
28. Ausubet FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. Enzyme-Linked Immunosorbent Assay (ELISA). In: Current Protocols in Molecular Biology. Ausubel FM et al., eds. John Wiley and Sons, Inc. New York, 1988, pp 11.2.2-11.2.5.
29. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction. Anal Biochem 1987; 162: 156-9.
30. Puissant C, Houdebine LM. An improvement of single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. BioTechniques 1990; 8: 148-9.
31. Ny T, Leonardsson G, Hsueh AJW. Cloning and characterization of a cDNA for rat tissue-type plasminogen activator. DNA 1988; 7: 671-7.
32. Zeheb R, Gelehrter TD. Cloning and sequencing of cDNA for the rat PAI-1. Gene 1988; 73: 459-86.
33. Fort P, Marty L, Piechaczyk M, Sabrouty SE, Dani CH, Jeanteur P, Blanchand JM. Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acid Res 1985; 13: 1431-42.
34. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983; 136: 6-13.
35. Todd AS. Fibrinolysis autographs. Nature 1958; 181: 495-6.
36. Deutsch DD, Mertz ET. Plasminogen: purification from human plasma by affinity chromatography. Science 1978; 170: 1095-6.
37. Johnson GD, Holborw EJ. Immunofluorescence. In: Handbook of Experimental Immunology. Weir DM, ed. Blackwell Scientific Inc., Oxford - London - Edinburgh - Melbouren, 1973; pp 18.0-18.20.
38. Rijken DC, Otter M, Kuiper J, van Berkel TJC. Receptor mediated endocytosis of tissue-type plasminogen activator (t-PA) by liver cells. Thromb Res 1990; 10: 63-71.
39. Otter M, Kuiper J, Bos R, Rijken DC, van Berkel TJC. Characterization of the interaction both in vitro and in vivo of tissue-type plasminogen activator (t-PA) with rat liver cells. Biochem J 1992; 284: 545-50.
40. 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator. Proc Natl Acad Sci USA 1992; 89: 7427-31.
41. Orth K, Willnow T, Herz J, Gething MJ, Sambrook J. Low density lipoprotein receptor-related protein is necessary for the internalization of both tissue-type plasminogen activator-inhibitor complexes and free tissue-type plasminogen activator. J Biol Chem 1994; 269: 21117-22.
42. Thornton AJ, Gelehrter TD. Human hepatocytes express the gene for type 1 plasminogen activator-inhibitor (PAI-1) in vivo. Fibrinolysis 1995; 9: 9-15.
43. Heaton JH, Kathju S, Gelehrter TD. Transcriptional and posttranscriptional regulation of type 1 plasminogen activator inhibitor and tissue-type plasminogen activator gene expression in HTC rat hepatoma cells by glucocorticoids and cyclic nucleotides. Mol Endocrinol 1992; 6: 53-60.
44. Kathju S, Heaton JH, Bruzdzinski CJ, Gelehrter TD. Synergistic induction of tissuetype plasminogen activator gene expression by glucocorticoids and cyclic nucleotides in rat HTC hepatoma cells. Endocrinology 1994; 135: 1195-204.
45. Schneiderman J, Sawdey M, Craig H, Thinnes T, Bordin G, Loskutoff DJ. Type 1 plasminogen activator inhibitor gene expression following partial hepatectomy. Am J Pathol 1993; 143: 753-62.
46. Kluft C, Verheijen JH, Jie AFH, Rijken DC, Preston FE, Sue-Ling HM, Jespersen J, Aasen AO. The postoperative fibrinolytic shutdown: a rapidly reverting acute phase pattern for the fast-acting inhibitor of tissue-type plasminogen activator after trauma. Scand J Clin Lab Invest 1985; 45: 605-10.
47. Juhan-Vague I, Aillaud MF, de Cock F, Philip Joet C, Arnaud C, Serradimigni A, Collen D. The fast-acting inhibitor of tissue plasminogen activator is an acute phase reactant protein. Prog in Fibrinol 1985; 7: 146-9.
48. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M. Sugimura A, Tashiro K, Shimizu S. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440-3.
49. Seki T, Hagiya M, Shimonishi M, Nakamura T. Organization of the human hepatocyte growth factor-encoding gene. Gene 1991; 102: 213-9.
50. Naldini L, Tamagnone L, Vigna E, Sachs M, Hartmann G, Birchmeiner, Daikuhara Y, Tsubouchi H, Blasi F, Comoglio PM. Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor EMBO J 1992; 11: 4825-33.
51. Mars WM, Zarnegar R, Michalopoulos GK. Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. Am J Pathol 1993; 143: 949-58.
52. Massague J. The transforming growth factor-β family. Annu Rev Cell Biol 1990; 6: 597-641.
53. Strain AJ, Frazer A, Hill DJ, Milner RD. Transforming growth factor beta inhibits DNA synthesis in hepatocytes isolated from normal and regenerating rat liver. Biochem Biophys Res Commun 1987; 145: 436-42.
54. Russell WE, Coffey RJJ, Oullette AJ, Moses HL. Type β transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Natl Acad Sci USA 1988; 85: 5126-30.
55. Westerhausen DRJ, Hopkins WE, Billadello JJ. Multiple transforming growth factor-β-inducible elements regulate expression of the plasminogen activator inhibitor type-1 gene in Hep G2 cells. J Biol Chem 1991; 266: 1092-100.
56. Wojta J, Nakamura T, Fabry A, Hufnagl P, Beckman R, McGrath K, Binder BR. Hepatocyte growth factor stimulates expression of plasminogen activator inhibitor type 1 and tissue factor in Hep G2 cells. Blood 1994; 84: 151-7.