Interference to human immunodeficiency virus type 1 infection in the absence of downmodulation of the principal virus receptor, CD4

Journal of Virology

Volumn 70, Issue 6, 1996, Pages 3823-3833

  Volsky, David J ^a,b   Simm, Malgorzata ^a   Shahabuddin, Muhammad ^a,c   Li, Gongrong ^a   Chao, Wei ^a   Potash, Mary Jane ^a  

^a Columbia University ^*  (United States)

^b ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RECEPTOR;

ARTICLE; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS CELL INTERACTION; VIRUS REPLICATION;

EID: 0029994033     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.6.3823-3833.1996     Document Type: Article

References (64)

1. Adachi, A., H. E. Gendelman, S. Koenig, T. Folks, R. Willey, A. Rabson, and M. A. Martin. 1986. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291.
2. Aiken, C., J. Konner, N. R. Landau, M. E. Lenburg, and D. Trono. 1994. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853-864.
3. Ausubet, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Strahl (ed.). 1989. Current protocols in molecular biology. John Wiley & Sons, New York.
4. Bauer, H., Y. Ting, C. Grier, J. Chambers, C. Tashiro, J. Chimera, A. Reingold, and M. Manos. 1991. Genital human papilloma virus infection in female university students as determined by a PCR-based method. JAMA 265:472-477.
5. Bedinger, P., A. Morlarty, R. von Borstel, N. Donovan, K. Steimer, and D. Littman. 1988. Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4. Nature (London) 234:162-165.
6. Benson, R. E., A. Sanfridson, J. S. Ottinger, C. Doyle, and B. R. Cullen. 1993. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus nef prevents viral super infection. J. Exp. Med. 177:1561-1566.
7. Bergeron, L., and J. Sodroski. 1992. Dissociation of unintegrated viral DNA accumulation from single-cell lysis induced by human immunodeficiency virus type 1. J. Virol. 66:5777-5787.
8. Bour, S., F. Boulerice, and M. A. Wainberg. 1991. Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1. J. Virol. 65:6387-6396.
9. Butera, S., V. L. Perez, B. Y. Wu, G. J. Nabel, and T. M. Folks. 1991. Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4 cell model of chronic infection. J. Virol. 65:4645-4653.
10. Caputo, A., J. G. Sodroski, and W. A. Haseltine. 1990. Constitutive expression of HIV-1 tat protein in human Jurkat T cells using a BK virus vector. J. Acquired Immune Defic. Syndr. 3:372-379.
11. Casareale, D., M. Stevenson, K. Sakai, and D. J. Volsky. 1987. A human T-cell line resistant to cytopathic effects of HIV-1. Virology 156:40-49.
12. Colicelli, J., and S. P. Goff. 1985. Mutants and pseudo revertants of Moloney murine leukemia virus with alterations at the integration site. Cell 42:573-580.
13. Crise, B., L. Buonocore, and J. K. Rose. 1990. CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor. J. Virol. 64:5585-5593.
14. Dalgleish, A. G., P. C. L. Beverley, P. R. Clapham, D. H. Crawford, M. F. Greaves, and R. A. Weiss. 1984. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature (London) 312:763-767.
15. Delwart, E., and A. Panganiban. 1989. Role of reticuloendotheliosis virus envelope glycoprotein in superinfection interference. J. Virol. 63:273-280.
16. Fan, H., R. Jaenisch, and P. MacIsaac. 1978. Low-multiplicity infection of Moloney murine leukemia virus in mouse cells: effect on number of viral DNA copies and virus production in producer cells. J. Virol. 28:802-809.
17. Francis, M., and M. Meltzer. 1993. Induction of IFN-alpha by HIV-1 in monocyte-enriched PBMC requires gp120-CD4 interaction but not virus replication. J. Immunol. 151:2208-2216.
18. Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature (London) 350:508-511.
19. Gendelman, H., L. Baca, J. Turpin, C. Kalter, B. Hansen, J. Orenstein, F. Diffenbach, R. Friedman, and M. Meltzer. 1991. Regulation of HIV replication in infected monocytes by IFN-alpha. J. Immunol. 145:2669-2676.
20. Gendelman, H. E., J. Orenstein, M. Martin, G. Gerrua, R. Mitra, T. Phipps, L. Wahl, C. Lane, A. Fauci, D. Burke, D. Skillman, and M. Meltzer. 1988. Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor-1 treated monocytes. J. Exp. Med. 167:1428-1441.
21. Ghosh, A., M. Bachmann, E. Hoover, and J. Mullins. 1992. Identification of a putative receptor for subgroup A feline leukemia virus on feline T cells. J. Virol. 66:3707-3714.
22. Golf, S. P. 1990. Retroviral reverse transcriptase: synthesis, structure, and function. J. Acquired Immune Defic. Syndr. 3:817-831.
23. Golub, E. I., G. Li, and D. J. Volsky. 1990. Differences in the basal activity of the long terminal repeat determine different replicative capacities of two closely related human immunodeficiency virus type 1 isolates. J. Virol. 64:3654-3660.
24. Hirt, B. 1967. Selective extraction of polyoma DNA from infected mouse cell culture. J. Mol. Biol. 26:365-369.
25. Hoxie, J., J. Alpers, J. Rackowksi, K. Huebner, B. Haggarty, A. Cedarbaum, and J. Reed. 1986. Alterations in T4 protein and mRNA synthesis in cells infected with HIV. Science 234:1123-1127.
26. Hsu, M.-C., A. D. Schutt, M. Holly, L. W. Slice, M. I. Sherman, D. D. Richman, M. J. Potash, and D. J. Volsky. 1991. Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist. Science 254:1799-1802.
27. Huang, Z.-B., M. J. Potash, M. Simm, M. Shahabuddin, W. Chao, H. E. Gendelman, E. Eden, and D. J. Volsky. 1993. Infection of macrophages with lymphotropic human immunodeficiency virus type 1 can be arrested after viral DNA synthesis. J. Virol. 67:6893-6896.
28. Inis, M. A., D. Gelfand, J. Sninsky, and T. While. 1990. PCR protocols. Academic Press, San Diego, Calif.
29. Jonak, Z. L., R. K. Clark, D. Matour, S. Trulli, R. Craig, E. Henri, E. V. Lee, R. Greig, and C. Debouck. 1993. A human lymphoid recombinant cell line with functional human immunodeficiency virus type 1 envelope. AIDS Res. Hum. Retroviruses 9:23-31.
30. Klatzmann, D., E. Champagne, S. Chamaret, J. Gruest, D. Guetard, T. Hercend, J.-C. Gluckman, and L. Montagnier. 1984. T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature (London) 312:767-771.
31. Kowalski, M., L. K. Bergeron, T. Dorfman, W. Haseltine, and J. Sodroski. 1991. Attenuation of human immunodeficiency virus type 1 cytopathic effect by a mutation affecting the transmembrane envelope glycoprotein. J. Virol. 65:281-291.
32. LeGuern, M., and J. Levy. 1992. HIV-1 can superinfect HIV-2 infected cells: pseudotype virions produced with expanded cellular host range. Proc. Natl. Acad. Sci. USA 89:363-367.
33. Lenburg, M. E., and N. R. Landau. 1993. Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4. J. Virol. 67:7238-7245.
34. Lori, F., F. D. M. Veronese, A. L. De Vico, P. Lusso, M. S. Reitz, Jr., and R. C. Gallo. 1992. Viral DNA carried by human immunodeficiency virus type 1 virions. J. Virol. 66:5067-5074.
35. Nielsen, D., T.-C. Chang, and D. Shapiro. 1989. A highly sensitive, mixed phase assay for chloramphenicol acetyltransferase activity in transfected cells. Anal. Biochem. 179:19-23.
36. Ott, D. E., R. Friedrich, and A. Rein. 1990. Sequence analysis of amphotropic and 10A1 murine leukemia viruses: close relationship to mink cell focus-inducing viruses. J. Virol. 64:757-766.
37. Pauza, D., J. Gallindo, and D. Richman. 1990. Reinfection results in accumulation of unintegrated viral DNA and persistent HIV-1 infection of CEM cells. J. Exp. Med. 172:1035-1042.
38. Pellegrino, M. G., G. Li, M. J. Potash, and D. J. Volsky. 1991. Contribution of multiple rounds of viral entry and reverse transcription to expression of human immunodeficiency virus type 1. J. Biol. Chem. 266:1783-1788.
39. Popovic, M., M. Sarngadharan, E. Read, and R. Gallo. 1984. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 224:497-500.
40. Potash, M. J., G. Li, M. Shahabuddin, M. G. Pellegrino, and D. J. Volsky. 1993. Human immunodeficiency virus type 1 infection requires reverse transcription of nascent viral RNA. DNA Cell Biol. 12:685-693.
41. Reinhart, T., A. Ghosh, E. Hoover, and J. Mullins. 1993. Distinct superinfection interference properties yet similar receptor utilization by cytopathic and noncytopathic feline leukemia viruses. J. Virol. 67:5153-3162.
42. Robinson, H., S. Astrin, A. Senior, and F. Salazar. 1981. Host susceptibility to endogenous viruses: defective glycoprotein-expressing proviruses interfere with infections. J. Virol. 40:745-751.
43. Robinson, H. L., and D. M. Zinkus. 1990. Accumulation of human immunodeficiency virus type 1 DNA in T cells: result of multiple infection events. J. Virol. 64:4836-4841.
44. 43a.Roth, M. Personal communication.
45. Sakai, K., S. Dewhurst, X. Ma, and D. J. Volsky. 1988. Differences in cytopathogenicity and host cell range among infectious molecular clones of human immunodeficiency virus type 1 simultaneously isolated from an individual. J. Virol. 62:4078-4085.
46. Sakai, K., X. Ma, I. Gordienko, and D. J. Volsky. 1991. Recombinational analysis of a natural noncytopathic human immunodeficiency virus type 1 (HIV-1) isolate: role of the vif gene in HIV-1 infection kinetics and cytopathicity. J. Virol. 65:5765-5773.
47. Sato, H., J. Orenstein, D. Dimitrov, and M. Martin. 1992. Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles. Virology 186:712-724.
48. Schmidtmayerova, H., C. Bolmont, S. Baghdiguian, I. Hirsch, and J.-C. Chermann. 1992. Distinctive pattern of infection and replication of HIV-1 strains in blood-derived macrophages. Virology 190:124-133.
49. Schreier, M., G. Koehler, H. Hengartner, C. Berek, M. Trucco, L. Forni, T. Staehlin, H. Stocker, and B. Takacs. 1980. Hybridoma techniques. Hoffmann-La Roche, Basel.
50. Shahabuddin, M., B. Volsky, M.-C. Hsu, and D. J. Volsky. 1992. Restoration of cell surface CD4 expression in human immunodeficiency virus type 1-infected cells by treatment with a Tat antagonist. J. Virol. 66:6802-6805.
51. Somasundaran, M., and H. Robinson. 1988. Unexpectedly high levels of HIV-1 RNA and protein synthesis in a cytocidal infection. Science 242:1554-1557. (Correction, 247:1531, 1990.)
52. Sova, P., and D. J. Volsky. 1993. Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1. J. Virol. 67:6322-6326.
53. Steck, F., and H. Rubin. 1966. The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. I. Establishment of interference. Virology 29:628-641.
54. Steck, F., and H. Rubin. 1966. The mechanism of interference between an avian leukosis virus and Rous sarcoma virus. II. Early steps of infection by RSV or cells under conditions of interference. Virology 29:642-653.
55. Stevenson, M., X. Zhang, and D. J. Volsky. 1987. Downregulation of cell surface molecules during noncytopathic infection of T cells with human immunodeficiency virus. J. Virol. 61:3741-3748.
56. Taddeo, B., M. Federico, F. Titti, G. B. Rossi, and P. Verani. 1993. Homologous superinfection of both producer and nonproducer HIV-infected cells is blocked at a late retrotranscription step. Virology 194:441-452.
57. Tchenio, T., and T. Heidman. 1991. Defective retroviruses can disperse in the human genome by intracellular transposition. J. Virol. 65:2113-2118.
58. Terwilliger, E., B. Godin, J. Sodroski, and W. Haseltine. 1989. Construction and use of a replication competent HIV-1 that expresses the chloramphenicol acetyltransferase gene. Proc. Natl. Acad. Sci. USA 86:3857-3861.
59. Trono, D. 1992. Partial reverse transcripts in virions from human immunodeficiency and murine leukemia viruses. J. Virol. 66:4893-4900.
60. Varmus, H. E., and P. B. Shank. 1976. Unintegrated viral DNA is synthesized in the cytoplasm of avian sarcoma virus-transformed duck cells by viral DNA polymerase. J. Virol. 18:567-573.
61. Vogt, P., and R. Ishizaka. 1966. Patterns of viral interference in the avian leukosis and sarcoma complex. Virology 30:368-374.58.
62. Volsky, D. J., M. Zeira, and A. Loyter. 1992. The mechanism of human immunodeficiency virus type 1 entry and fusion as determined by fluorescence dequenching: similarities with parainfluenza virus and implications for cytopathology in acquired immune deficiency syndrome, p. 167-186. In R. Aloia (ed.). Membrane interactions of HIV. Wiley-Liss, Inc., New York.
63. Weiss, R. 1985. Experimental biology and assay of RNA tumor viruses, p. 236-245. In R. Weiss, N. Teich, H. Varmus, and J. Coffin (ed.). RNA tumor viruses. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
64. Willey, R. L., F. Maldarelli, M. A. Martin, and K. Strebel. 1992. Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. J. Virol. 66:7193-7200.