Lack of rearranged Tpr-met mRNA expression in human gastric cancer cell lines and gastric mucosa and carcinoma

Anticancer Research

Volumn 16, Issue 5 A, 1996, Pages 2881-2884

  Osaki, Mitsuhiko ^a,b   Miyata, Hironori ^b   Hayashi, Atsushi ^a   Gomyo, Yoshihito ^a   Tatebe, Shigeru ^a   Ito, Hisao ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

Gastric cancer; RT PCR; tpr met mRNA

Indexed keywords

MESSENGER RNA;

ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; CANCER CELL CULTURE; DNA SEQUENCE; GENE EXPRESSION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE METAPLASIA; NORMAL HUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH CARCINOMA; STOMACH MUCOSA;

ADENOCARCINOMA; BASE SEQUENCE; CARCINOMA, PAPILLARY; CARCINOMA, SIGNET RING CELL; GASTRIC MUCOSA; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR PORE COMPLEX PROTEINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0029993840     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Bottaro DP, Rubin JS, Faletto DL, Chan AM-L, Kmiecik TE, Vande Woude GF, Aaronson SA: Identification of the hepatocyte growth facter receptor as the c-met proto- oncogene product. Science 251: 802-804, 1991.
2. Park M, Dean M, Cooper CS, Schmidt M, O'brien SJ, Blair DG, Vande Woude GF: Mechanism of met oncogene activation. Cell 45: 895-904, 1986.
3. Cooper CS, Park M, Blair DG, Tainsky MA, Huehner K, Croce CM, Vande Woude GF: Molecular cloning of a new transforming gene from a chemically-transformed human cell line. Nature 311: 29-33, 1984.
4. Gonzatti-Hances M, Seth A, Park M, Copeland T, Oroszlan S, Vande Woude GF: Caracterization of the tpr-met oncogene p65 and the met protooncogene p140 protein-tyrosine kinases. Proc Natl Acad Sci USA 85: 21-25, 1988.
5. Soman NR, Wogan GN, Rhim JS: TPR-MET oncogenic rearrangement: Detection by polymerase chain reaction amplification of the transcript and expression in human tumor cell lines. Proc Natl Acad Sci USA 87: 738-742, 1990.
6. Soman NR, Correa P, Ruiz BA, Wogan GN: The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions. Proc Natl Acad Sci USA 88: 48-92-48-96, 1991.
7. Hojo H: Establishment of cultured cell lines of human stomach cancer origin and their morphological characteristics. Niigata Igakkai Zassi 91: 737-752, 1977.
8. Minoda J, Ohnuma T, Moore GE: Rosette-forming human lymphoid cell lines-Establishment and evidence for origin of thymus-derived lymphocytes. J Natl Cancer Inst 49: 891-895, 1972.
9. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
10. Chan AM-L, King HWS, Tempest PR, Deakin EA, Cooper CS, Brookes P: Primary structure of the met protein tyrosine kinase domain. Oncogene 1: 229-233, 1987.
11. Gubler U: A one tube reaction for the synthesis of blunt-ended double-stranded cDNA. Nucl Acid Res 6: 27-26, 1988.
12. Marchuk D, Drumm M, Saulino A, Collins FS: Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products. Nucl Acids Res 19: 11-54, 1991.
13. Dean M, Park M, LeBeau M, Robins T, Diaz M, Rowley J, Blair DG, Vande Woude GF: The human met oncogene is related to the tyrosine kinase oncogenes. Nature 318: 385-388, 1985.
14. Comoglio PM: Structure, biosynthesis and biochemical properties of the HGF receptor in nomal and malignant cells. In: Goldberg ID, Rosen EM, eds. Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and the c-Met Receptor. Basel, Birkauser Verrag, 1993, pp131-165.
15. Naldini L, Vigna E, Narsimham RP, Gaudino G, Zarnegar R, Michalopoulos GK, Comoglio PM: Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene 6: 501-504, 1991.
16. Naldini L, Weidner KM, Vigna E, Gaudino G, Bardelli A, Ponzetto C, Narsimhan RP, Hartmann G, Zarnegar R, Michalopoulos GK, Birchmeier W, Comoglio PM: Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J 10: 2867-2878, 1991.
17. Kuniyasu H, Yasui W, Kitadai Y, Yokozaki H, Ito H, Tahara E: Frequent amplification of the c-met gene in scirrhous type stomach cancer. Biochem Biophys Res Commun 189: 227-232, 1992.
18. Kuniyasu H, Yasui W, Yokozaki H, Kitadai Y, Tahara E: Aberrant expression of c-met mRNA in human gastric carcinomas. Int J Cancer 55: 72-75, 1993.