Control by H-2 genes of the Th1 response induced against a foreign antigen expressed by attenuated Salmonella typhimurium

Infection and Immunity

Volumn 64, Issue 11, 1996, Pages 4424-4432

  Lo Man, Richard ^a   Martineau, Pierre ^a,b   Dériaud, Edith ^a   Newton, Salete M ^a,c   Jehanno, Muguette ^a   Clément, Jean Marie ^a   Fayolle, Catherine ^a   Hofnung, Maurice ^a   Leclerc, Claude D ^a  

^a INSTITUT PASTEUR   (France)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; GENE CONTROL; MICROBIAL ATTENUATION; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; VACCINATION;

EID: 0029993813     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.11.4424-4432.1996     Document Type: Article

References (65)

1. + cytotoxic T cells. J. Exp. Med. 172:1083-1090.
2. AI-Ramadi, B. K., J. J. Meisler, Jr., D. Huang, and T. K. Eisenstein. 1992. Imtnunosuppression induced by nitric oxide and its inhibition by interleukin-4. Eur. J. Immunol. 22:2249-2254.
3. Anjam Khan, C. M., B. Villarreal-Ramos, R. J. Pierce, R. Demarco de Hormaeche, H. McNeil, T. Ali, S. Chatfleld, A. Capron, G. Dougan, and C. E. Hormaeche. 1994. Construction, expression and immunogenicity of multiple tandem copies of the Schistosoma mansoni peptide 115-131 of the P28 glutathione S-transferase expressed as C-terminal fusions to tetanus toxin fragment C in a live Aro-attenuated vaccine strain of Salmonella. J. Immunol. 153:5634-5642.
4. Benacerraf, B., and H. O. McDevitt. 1982. Histocompatibility linked immune response genes. Science 175:273-279.
5. Bost, K. L., and J. D. Clements. 1995. In vivo induction of interleukin-12 mRNA expression after oral immunization with Salmonella dublin or the B subunit of Escherichia coli heat-labile enterotoxin. Infect. Immun. 63:1076-1083.
6. Brett, S. J., L. Dunlop, F. Y. Liew, and J. P. Tite. 1993. Influence of the antigen delivery vehicle on immunoglobulin isotype selection and cytokine production in response to influenza nucleoprotein. Immunology 80:306-312.
7. Briles, D. E., W. Benjamin, Jr., B. Posey, S. M. Michalek, and J. R. McGhee. 1986. Independence of macrophage activation and expression of the Ity locus. Microb. Pathog. 1:33-41.
8. Brown, A., C. E. Hormaeche, R. Demarco de Hormaeche, M. Winther, C. Dougan, D. J. Maskell, and B. A. D. Stocker. 1987. An attenuated aroA Salmonella typhimurium vaccine elicits humoral and cellular immunity to cloned β-galactosidase in mice. J. Infect. Dis. 155:86-92.
9. Charbit, A., P. Martineau, J. Ronco, C. Leclerc, R. Lo-Man, V. Michel, D. O'Callaghan, and M. Hofnung. 1993. Expression and immunogenicity of the V3 loop from the envelope of human immunodeficiency virus type 1 in an attenuated aroA strain of Salmonella typhimurium upon genetic coupling to two E. coli carrier proteins. Vaccine 11:1221-1228.
10. Chatfleld, S. N, R. A. Strugnell, and G. Dougan. 1989. Live Salmonella as vaccines and carriers of foreign antigenic determinants. Vaccine 7:495-498.
11. Curtiss, R., III. 1990. Attenuated Salmonella strains as live vectors for the expression of foreign antigens, p. 161-188. In G. C. Woodrow and M. M. Levine (ed.), New-generation vaccines. Marcel Dekker, Inc., New York.
12. Denich, K., P. Berlin, P. D. O'Hanley, M. Howard, and A. W. Heath. 1993. Expression of the murine IL-4 gene in an attenuated aroA strain of Salmonella typhimurium: persistence and immune response in BALB/c mice and susceptibility to macrophage killing. Infect. Immun. 61:4818-4827.
13. Eisenstein, T. K., L. W. Deakins, L. Killar, P. H. Saluk, and B. M. Sultzer. 1982. Dissociation of innate susceptibility to Salmonella infection and endotoxin responsiveness in C3HeB/FcJ mice and other strains in the C3H lineage. Infect. Immun. 36:696-703.
14. Eisenstein, T. K., L. M. Killar, B. A. Stocker, and B. M. Sultzer. 1984. Cellular immunity induced by avirulent Salmonella in LPS-defective C3H/ HeJ mice. J. Immunol. 133:958-961.
15. Evavold, B. D., and P. M. Allen. 1991. Separation of IL-4 production from Th cell proliferation by an altered receptor ligand. Science 252:1308-1310.
16. Fairweather, N. F., S. N. Chatfield, A. J. Makoff, R. A. Strugnell, J. Bester, D. J. Maskell, and G. Dougan. 1990. Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier. Infect. Immun. 58:1323-1326.
17. - T cell help. J. Immunol. 147:4069-4073.
18. Fayolle, C., D. O'Callaghan, P. Martineau, A. Charbit, J. M. Clement, M. Hofnung, and C. Leclerc. 1994. Genetic control of antibody responses induced against an antigen delivered by recombinant attenuated Salmonella typhimurium. Infect. Immun. 62:4310-4319.
19. Flexner, C., and B. Moss. 1990. Attenuated Salmonella strains as live vectors for the expression of foreign antigens, p. 189-206. In G. C. Woodrow and M. M. Levine (ed.), New-generation vaccines. Marcel Dekker, Inc., New York.
20. Flynn, J. L., W. R. Weiss, K. A. Norris, H. S. Seifert, S. Kumar, and M. So. 1990. Generation of a cytotoxic T-lymphocyte response using a Salmonella antigen-delivery system. Mol. Microbiol. 4:2111-2118.
21. Gonzalez, C., D. Hone, F. R. Noriega, C. O. Tacket, J. R. Davis, G. Losonsky, J. P. Nataro, S. Hoffman, A. Malik, E. Nardin, M. D. Sztein, D. G. Heppner, T. R. Fouts, A. Isibasi, and M. M. Levine. 1994. Salmonella typhi vaccine strain CVD 908 expressing the circumsporozoite protein of Plasmodium falciparum: strain construction and safety and immunogenicity in humans. J. Infect. Dis. 169:927-931.
22. Heinzel, F. P., M. D. Sadick. B. J. Holaday. R. L. Coffman. and R. M. Locksley. 1989. Reciprocal expression of interferon γ or interleukin 4 during the resolution or progression of murine leishmaniasis. J. Exp. Med. 169:59-72.
23. Heinzel, F. P., D. S. Schoenhaut, R. M. Rerko, L. E. Rosser, and M. K. Gately. 1993. Recomhinant interleukin 12 cures mice infected with Leishmania major. J. Exp. Med. 177:1505-1509.
24. Hess, J., I. Gentschev, D. Miko, M. Welzel, C. Ladel, W. Goebel, and S. H. E. Kaufmann. 1996. Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection. Proc. Natl. Acad. Sci. USA 93:1458-1463.
25. Hofnung, M., and A. Charbit. 1993. Expression of antigens as recornbinant proteins, p. 79-127. In V. H. M. Van Regenmortel (ed.), Sructures of antigens. CRC Press, Inc., Boca Raton, Fla.
26. Hoiseth, S. K., and B. A. D. Stocker. 1981. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature (London) 291:238-239.
27. Hormaeche, C. E. 1979. Natural resistance to Salmonella typhimurium in different inbred mouse strains. Immunology 37:311-318.
28. Hormaeche, C. E., K. A. Harrington, and H. S. Joysey. 1985. Natural resistance to salmonellae in mice: control by genes within the major histocompatibility complex. J. Infect. Dis. 152:1050-1056.
29. Kagaya, K., K. Walanabe, and Y. Fnkazawa. 1989. Capacity of recornbinant gamma interferon to activate macrophages for Salmonella-killing activity. Infect. Immun. 57:609-615.
30. Khoo, S. H., J. St. Clair Roberts, and B. K. Mandal. 1995. Safety and efficacy of combined meningococcal and typhoid vaccine. Br. Med. J. 310:908-909.
31. Killar, L. M., and T. K. Eisenstein. 1985. Immunity to Salmonella typhimurium infection in C3H/HeJ and C3H/HeNCrIBR mice: studies with an aromatic-dependent live S. typhimurium strain as a vaccine. Infect. Immun. 47:605-612.
32. Killar, L. M., and T. K. Eisenstein. 1986. Delayed-type hypersensitivity and immunity to Salmonella typhimurium. Infect. Immun. 52:504-508.
33. Leclerc, C., A. Charbit, P. Martineau, E. Dériaud, and M. Hofnung. 1991. The cellular location of a foreign B cell epitope expressed by recornbinant bacteria determines its T cell-independent or T cell-dependent characteristics. J. Immunol. 147:3545-3552.
34. Leclerc, C., P. Martineau, S. Van der Werf, E. Dériaud, P. Duplay, and M. Hofnung. 1990. Induction of virus-neutralizing antibodies by bacteria expressing the C3 poliovirus epitope in the periplasm. J. Immunol. 144:3174-3182.
35. Lo-Man, R., et al. Unpublished data.
36. Lo-Man, R., P. Martineau, J. M. Betton, M. Hofnung, and C. Leclerc. 1994. Molecular context of a viral T cell determinant within a chimeric bacterial protein alters the diversity of its T cell recognition. J. Immunol. 152:5660-5669.
37. Lo-Man, R., P. Martineau, M. Hofnung, and C. Leclerc. 1993. Induction of T cell responses by chimeric bacterial proteins expressing several copies of a viral T cell epitope. Eur. J. Immunol. 23:2998-3002.
38. Martineau, P., J. G. Guillet, C. Lecierc, and M. Hofnung. 1992. Expression of heterologous peptides at two permissive sites of the MalE protein: anti-genicity and immunogenicity of foreign B-cell and T-cell epitopes. Gene 113:35-46.
39. - salmonella vaccines. Microb. Pathog. 13:477-491.
40. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
41. Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:2348-2357.
42. + T cells and T-independent mechanisms in acquired resistance to salmonella infection. J. Immunol. 145:1265-1269.
43. Nauciel, C, E. Ronco, J. L. Guénet, and M. Pla. 1988. Role of H-2 and non-H-2 genes in control of bacterial clearance from the spleen in Salmonella typhimurium-infected mice. Infect. Immun. 56:2407-2411.
44. Newton, S. M., C. O. Jacob, and B. A. Stocker. 1989. Immune response to cholera toxin epitope inserted in Salmonella flagellin. Science 244:70-72.
45. Newton, S. M., M. Kotb, T. P. Poirier, B. A. Stocker, and E. H. Beachey. 1991. Expression and immunogenicity of a streptococcal M protein epitope inserted in Salmonella flagellin. Infect. Immun. 59:2158-2165.
46. O'Brien, A. D., and D. L. Rosenstreich. 1983. Genetic control of the susceptibility of C3HeB/FeJ mice to Salmonella typhimurium is regulated by a locus distinct from known salmonella response genes. J. Immunol. 131:2613-2615.
47. O'Brien, A. D, D. L. Rosenstreich, I. Sher, G. H. Campbell, R. P. MacDermott, and S. B. Formal. 1980. Genetic control of susceptibility to Salmonella typhimurium in mice: role of the Lps gene. J. Immunol. 124:20-24.
48. O'Brien, A. D., I. Sher, and E. S. Metcalf. 1981. Genetically conferred defect in anti-salmonella antibody formation renders CBA/N innately susceptible to Salmonella typhimurium infection. J. Immunol. 126:1368-1372.
49. Poirier, T. P., M. A. Kehoe, and E. H. Beachey. 1988. Protective immunity evoked by oral administration of attenuated aroA Salmonella typhimurium expressing cloned streptococeal M protein. J. Exp. Med. 168:25-32.
50. Ramarathinam, L., D. W. Niesei, and G. R. Klimpel, 1993 Salmonella typhimurium induces IFN-gamma production in murine splenocytes. J. Immunol. 150:3973-3981.
51. Schneider, E., L. Bishop, E. Schneider, V. Alfanrtary, and G. F. Ames. 1989. Fine-structure genetic map of the maltose transport operon of Salmonella typhimurium. J. Bacterial. 171:5860-5865.
52. Seder, A. A., and W. E. Paul. 1994. Acquisition of lymphokine producing phenotype by CD4 T cells. Annu. Rev. Immunol. 12:635-673.
53. Swanson, R. N., and A. D. O'Brien. 1983. Genetic control of the resistance of mice to Salmonella typhimurium: Ity gene is expressed in vivo by 24 h after infection. J. Immunol. 131:3014-3020.
54. Sztein, M. B., S. S. Wasserman, C. O. Tacket, R. Edelman, D. Hone, A. A. Lindberg, and M. M. Levine. 1994. Cytokine production patterns and lymphoproliferative responses in volunteers orally immunized with attenuated vaccine strains of Salmonella typhi. J. Infect. Dis. 170:1508-1517.
55. Tacket, C. O., B. Forrest, R. Morona, S. R. Attridge, J. Labroody, B. D. Tall, M. Keymann. D. Rowley, and M. M. Levine. 1990. Safety, immunogcnicity, and efficacy against cholera challenge in humans of a typhoid-cholera hybrid vaccine derived from Salmonella typhi 21a. Infect. Immun. 58:1620-1627.
56. Tite, J. P., X. M. Gao, C. M. Hughes-Jenkins, M. Lipseorabe, D. O'Callaghan, G. Dnugan, and F. Y. Liew. 1990. Anti-viral immunity induced by recombinant nucleaprotein of influenza A virus. III. Delivery of recombinant nutleoprotein to the immune system using attenuated Salmonella typhimurium as a live carrier. Immunology 70:540-546.
57. Tite, J. P., S. M. Russel, G. Dougan, D. O'Callaghan, I. Jones, G. Brownlee, and F. Y. Liew. 1988. Antiviral immunity induced by recombinant nucleaprotein of influenza A virus. J. Immunol. 141:3980-3987.
58. VanCott, J. L., H. F. Staats, D. W. Paseual, M. Roberts, S. N. Chatfield, M. Yamamoto, M. Coste, P. B. Carter, H. Kiyono, and J. R. McGhee. 1916 Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J. Immunol. 156:1504-1514.
59. Van de Verg, L., D. A. Herrington, J. R. Murphy, S. S. Wasserman, S. B. Formal, and M. M. Levine. 1990. Specific immunoglobulin A-secreting cells in peripheral blood of humans following oral immunization with a bivalent Salmonella typhi-Shigella sonnei vaccine or infection by pathogenic S. sonnei. Infect. Immun. 58:2002-2004.
60. Vaz, N. M., and B. B. Levine. 1970. Immune responses to inbred mice to repeated low doses of antigen: relationship to histocompatibility (H-2) typo. Science 168:852-854.
61. Verjans, G. M. G. M., R. Janssen, F. G. C. M. UytdeHaag, C. E. M. van Doornik, and J. Tommassen. 1995. Intracellular processing and presentation of T cell epitopes, expressed by recombinant E. coli and S. typhimurium, to human T cells. Eur. J. Immunol. 25:405-410.
62. Verma, N. K., H. K. Ziegler, B. A. D. Stocker, and G. K. Schoolnik. 1995. Delivery of class I and class II MHC restricted T cell epitopes of listeriolysin of L monocytogenes by attenuated salmonella. Vaccine 13:142-150.
63. Wick, M. J., C. V. Harding, S. J. Normark, and J. D. Pfeifer. 1994. Parameters that influence the efficiency of processing antigenic epitopes expressed in Salmonella typhimurium. Infect. Immun. 62:4542-4548.
64. Woodrow, G. C., and M. M. Levine (ed.), 1990. New-generation vaccines, p. 231-459. Marcel Dekker, Inc., New York.
65. Yang, D. M., N. Fairweather, L. L. Button, W. R. McMaster, L. P. Kahl, and F. Y. Liew. 1990. Oral Salmonella typhimurium (AroA ) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis. J. Immunol. 145:2281-2285.