Isolation and characterization of a new rat P450 (CYP3A18) cDNA encoding P4506β-2 catalyzing testosterone 6β- and 16α- hydroxylations

Pharmacogenetics

Volumn 6, Issue 1, 1996, Pages 103-111

  Nagata, Kiyoshi ^b   Murayama, Norie ^a   Miyata, Masaaki ^a   Shimada, Miki ^b   Urahashi, Atsushi ^c   Yamazoe, Yasushi ^b   Kato, Ryuichi ^a  

^a KEIO UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c Amersham Central Laboratory   (Japan)

Author keywords

A male dominant expression; Cytochrome b5; Recombinant CYP3A; Testosterone 16 hydroxylation

Indexed keywords

16ALPHA CYANOPREGNENOLONE; 3 METHYLCHOLANTHRENE; COMPLEMENTARY DNA; CYTOCHROME P450 ANTIBODY; CYTOCHROME P450 ISOENZYME; DEXAMETHASONE; ENZYME ANTIBODY; MESSENGER RNA; PHENOBARBITAL; RECOMBINANT PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA LIBRARY; GEL ELECTROPHORESIS; GENE EXPRESSION; GENETIC TRANSFECTION; HYDROXYLATION; LIVER; MALE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; TESTOSTERONE METABOLISM;

AMINO ACID SEQUENCE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; BLOTTING, NORTHERN; CATALYSIS; CELL LINE; CLONING, MOLECULAR; CRICETINAE; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B5; DNA, COMPLEMENTARY; FEMALE; HYDROXYLATION; MALE; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RNA, MESSENGER; STEROID HYDROXYLASES; TESTOSTERONE; TRANSFECTION;

ANIMALIA; CRICETINAE;

EID: 0029993673     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199602000-00009     Document Type: Article

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