The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism

Journal of Molecular Biology

Volumn 257, Issue 5, 1996, Pages 1042-1051

  Domínguez, Roberto ^a   Souchon, Hélène ^a   Lascombe, Marie Bernard ^a   Alzari, Pedro M ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Catalytic mechanism; cis peptide bond; Evolution; Induced fit; Protein carbohydrate interactions

Indexed keywords

GLUCAN SYNTHASE; MUTANT PROTEIN;

ALPHA HELIX; ARTICLE; BETA CHAIN; CLOSTRIDIUM THERMOCELLUM; COMPARATIVE STUDY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME SUBSTRATE COMPLEX; GENETIC CONSERVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; R FACTOR;

CLOSTRIDIUM THERMOCELLUM;

EID: 0029993491     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0222     Document Type: Article

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