Lack of interaction between bromfenac and methotrexate in patients with rheumatoid arthritis

Journal of Rheumatology

Volumn 23, Issue 6, 1996, Pages 984-989

  Gumbhir Shah, Kavita ^a,b   Cevallos, William H ^a,b   DeCleene, Sheryl A ^a,b   Korth Bradley, Joan M ^a,b  

^a WYETH AYERST RESEARCH   (United States)

^b Dept of Clinical Pharmacokinetics ^*

Author keywords

BROMFENAC; INTERACTION; METHOTREXATE; PHARMACOKINETICS; RHEUMATOID ARTHRITIS

Indexed keywords

BECLOMETASONE DIPROPIONATE; BROMFENAC; CONJUGATED ESTROGEN; CORTISONE; ENALAPRIL MALEATE; HYDROXYCHLOROQUINE; LEVOTHYROXINE SODIUM; MEDROXYPROGESTERONE ACETATE; METHOTREXATE; PARACETAMOL; PREDNISONE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG SAFETY; DYSPEPSIA; FEMALE; HEADACHE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPERTENSION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ADULT; ANALGESICS; ARTHRITIS, RHEUMATOID; BENZOPHENONES; BROMOBENZENES; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; METHOTREXATE; MIDDLE AGED;

EID: 0029993203     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Sancilio LF, Nolan JC, Wagner LE, Ward JW: The analgesic and antiinflammatory activity and pharmacologic properties of bromfenac. Arzneimittelforschung 1987;37:513-9.
2. McQuay HJ, Carroll D, Frankland T, Harvey M, Moore A: Bromfenac, acetaminophen, and placebo in orthopedic postoperative pain. Clin Pharmacol Ther 1990;47:760-6.
3. Forbes JA, Edquist IA, Smith FG, Schwartz MK, Beaver WT: Evaluation of bromfenac, aspirin, and ibuprofen in postoperative oral surgery pain. Pharmacotherapy 1991;11:64-70.
4. Forbes JA, Beaver WT, Jones KF, et al: Analgesic efficacy of bromfenac, ibuprofen, and aspirin in postoperative oral surgery pain. Clin Pharmacol Ther 1992;51:343-52.
5. Nolan JC, Osman MA, Cheng LK, Sancilio LF: Bromfenac, a new nonsteroidal anti-inflammatory drug: Relationship between the anti-inflammatory and analgesic activity and plasma drug levels in rodents. J Pharmacol Exp Ther 1990;254:104-8.
6. Wajdula JS, Vavra I, Sullivan D, Ermer J, Osman M: Bromfenac. In: Lewis AJ, Furst DE, eds. Nonsteroidal Anti-inflammatory Drugs: Mechanisms and Clinical Uses. New York: Marcel Dekker Inc, 1994:267-84.
7. Shen DD, Azarnoff DL: Clinical pharmacokinetics of methotrexate. Clin Pharmacokinet 1978;3:1-13.
8. Sinnett MJ, Groff GD, Raddatz DA, Franck WA, Bertino JS Jr: Methotrexate pharmacokinetics in patients with rheumatic arthritis. J Rheumatol 1989;16:745-8.
9. Edelman J, Biggs DF, Jamali F, Russell AS: Low-dose methotrexate kinetics in arthritis. Clin Pharmacol Ther 1984;35:382-6.
10. Herman RA, Veng-Pedersen P, Hoffman J, Koehnke R, Furst DE: Pharmacokinetics of low-dose methotrexate in rheumatoid arthritis patients. J Pharm Sci 1989;78:165-71.
11. Seideman P, Beck O, Eksborg S, Wennberg M: The pharmacokinetics of methotrexate and its 7-hydroxy metabolite in patients with rheumatoid arthritis. Br J Clin Pharmacol 1995;35:409-12.
12. Jacobs SA, Stoller RG, Chabner BA, Johns DG: 7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate. J Clin Invest 1976;57:534-8.
13. Furst DE, Herman RA, Koehnke R, et al: Effect of aspirin and sulindac on methotrexate clearance. J Pharm Sci 1990;79:782-6.
14. Ahern M, Booth J, Loxton A, McCarthy P, Meffin P, Kevat S: Methotrexate kinetics in rheumatoid arthritis: Is there an interaction with nonsteroidal antiinflammatory drugs? J Rheumatol 1988;15:1356-60.
15. Stewart CF, Fleming RA, Bernard FG, Seleznick MJ, Evans WE: Aspirin alters methotrexate disposition in rheumatoid arthritis patients. Arthritis Rheum 1997;34:1514-20.
16. Tracy TS, Krohn K, Jones DR, Bradley JD, Hall SD, Brater DC: The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis. Eur J Clin Pharmacol 1992;42:121-5.
17. Cockcroft DW, Gault MH: Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
18. Osman MA, Dunning LK, Cheng LK, Wright GJ: Determination of bromfenac in plasma by high-performance liquid chromatography. J Chromatogr 1989;489:452-8.
19. Jusko WJ: Guidelines for collection and analysis of pharmacokinetic data. In: Evans WE, Schentag JJ, Jusko WJ, eds. Applied Pharmacokinetics. Principles of Therapeutic Drug Monitoring, 3rd ed. Spokane: Applied Therapeutics, 1992:2-1-2-43.
20. Jacobs SA, Stoller RG, Chabner BA, Johns D: Dose-dependent metabolism of methotrexate in man and rhesus monkeys. Cancer Treat Rep 1977;61:651-6.
21. Christophidis N, Louis WJ, Lucas I, Moon W, Vajda FJE: Renal clearance of methotrexate in man during high-dose oral and intravenous infusion therapy. Cancer Chemother Pharmacol 1981;6:59-64.