B cell-specific activation of the Epstein-Barr virus-encoded C promoter compared with the wide-range activation of the W promoter

Journal of General Virology

Volumn 77, Issue 6, 1996, Pages 1159-1162

  Contreras Brodin, Bertha ^a   Karlsson, Ann ^a   Nilsson, Tina ^b   Rymo, Lars ^b   Klein, George ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; VIRUS ANTIGEN;

ARTICLE; B LYMPHOCYTE; BURKITT LYMPHOMA; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; EPSTEIN BARR VIRUS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYBRID CELL; LYMPHOBLASTOID CELL LINE; LYMPHOMA CELL LINE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSACTIVATION; VIRUS TRANSCRIPTION;

HUMAN HERPESVIRUS 4;

EID: 0029993120     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-77-6-1159     Document Type: Article

References (21)

1. ALTIOK, E., MINAROVITS, J , HU, L. F., CONTRERAS-BRODIN, B., KLEIN, G. & ERNBERG, I. (1992). Host cell phenotype dependent control of the BCR2-BWR1 promoter complex regulates the Epstein-Barr virus nuclear antigens 2-6. Proceedings of the National Academy of Sciences, USA 89, 905-909.
2. BAER, R., BANKIER, A. T., BIGGIN, M. D., DEINTNGER, P. L., FARRELL, P. J., GIBSON, T. J., HATFULL, G. S., SATCHWELL, S. C., SEGUIN, C., TUFFNELL, P. S. & BARREL, B. G. (1984). DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310, 207-211.
3. BODESCOT, M., PERRICAUDET, M. & FARRELL, P. J. (1987). A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus. Journal of Virology 61, 3424-3430.
4. CONTRERAS-BRODIN, B., ANVRET, M., IMREH, S., ALTIOK, E., KLEIN, G. & MASUCCI, M. (1991). B cell phenotype-dependent expression of the Epstein-Barr virus nuclear antigens EBNA-2 to EBNA-6: studies with somatic cell hybrids. Journal of General Virology 72, 3025-3033.
5. ERNBERG, I , FALK, K., MINAROVITS, J., BUSSON, P., TURSZ, T., MASUCCI, M. G. & KLEIN. G. (1989). The role of methylation in the phenotype-dependent modulation of Epstein-Barr nuclear antigen 2 and latent membrane protein genes in cells latently infected with Epstein-Barr virus. Journal of General Virology 70, 2989-3002.
6. HENKEL, T , LING, P. D., HAYWARD, S. D. & PETERSON, M. G. (1994). Mediation of Epstein-Barr virus EBNA-2 transactivation by recombination signal-binding protein J Kappa. Science 169, 188-190.
7. JIN, X. W. & SPECK, S. (1992). Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter. Journal of Virology 66, 2846-2852.
8. KIEFF, E., WANG, F., BIRKENBACH, M., COHEN, J., SAMPLE, J., TOMKINSON, B., SWAMINATHAN, S., LONGNECKER, R., M ARCHINI, A., MANNICK, J., TSANG, S., SAMPLE, C. & KURILLA, M. (1991). Molecular biology of lymphocyte transformation by Epstein-Barr virus. In Origins of Human Cancer: A Comprehensive Review, pp. 563-576. Edited by J. Brigge, T. Curran, E. Harlow & F. McCormack. New York : Cold Spring Harbor Laboratory.
9. LING, P.D., RAWLINS, D. R & HAYWARD, S.D. (1993). The Epstein-Barr virus immortalizing protein EBNA-2 is targeted to DNA by a cellular enhancer binding protein. Proceedings of the National Academy of Sciences, USA 90, 9237-9241.
10. NILSSON, T., SJÖBLOM, A., MASUCCI, M. G. & RYMO, L. (1993). Viral and cellular factors influence the activity of the Epstein-Barr virus BCR2 and BWRl promoters in cells of different phenotype. Virology 193, 774-785.
11. RICKSTEN, A., OLSSON, A., ANDERSSON, T. & RYMO, L. (1988). The 5́ flanking region of the gene for the Epsein-Barr virus-encoded nuclear antigen 2 contains a cell type specific lu-acting regulatory element that activates transcription in transfected B cells. Nucleic Acids Research 16, 8391-8410.
12. ROBERTSON, E., GROSSMAN, S., JOHANSSEN, E., MILLER, C., LIN, J., TOMKINSON, B. & KIEFF, E. (1995). Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence specific DNA-binding protein JK. Journal of Virology 69, 3108-3116.
13. ROONEY, C., BRIMMELL, M., BUSCHLE, M., GORDON, A., FARRELL, P. J. & KOLMAN, J. (1992). Host cell and EBNA-2 regulation of Epstem-Barr virus latent cycle promoter activity in B-lymphocytes. Journal of Virology 66, 496-504.
14. ROWE, D. T., ROWE, M., EVAN, G. I., WALLACE, L. E., FARRELL, P. J. & RICKINSON, A. B. (1986). Restricted expression of EBV latent genes and T-lymphocyte detected membrane antigen in Burkitt lymphoma cells. EMBO Journal 5, 2599-2607.
15. SAMPLE, J., HUMMEL, M., BRAUN, D., BIRKENBACH, M. & KIEFF, E. (1986) Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins. A probable transcriptional initiation site. Proceedings of the National Academv of Sciences, USA 83, 5096-5100
16. SAMPLE, J., BROOKS, L., SAMPLE, C., YOUNG, L., ROWE, M., GREGORY, C., RICKINSON, A. & KIEFF, E. (1991). Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen l transcriptional activation site. Proceedings of the National Academy of Sciences, USA 88, 6343-6347.
17. SPECK, S. H., PFITZNER, A. J. & STROMTNGER, J. L. (1986). An Epstein-Barr virus transcript from a latently infected growth transformed B-cell line encodes a highly repetitive polypeptide. Proceedings of the National Academy of Sciences, USA 83, 9298-9302.
18. SUNG, N. S., KENNEY, S , GUTSCH, D. & PAGANO, J S. (1991). EBNA2 transactivates a lymphoid specific enhancer in the BamHl C promoter of Epstein-Barr virus. Journal of Virology 65, 2164-2169.
19. SUGDEN, B. & WARREN, N. (1989). A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1; a viral protein required for viral DNA replication during latent infection. Journal of Virology 63, 2664-2649.
20. WOISETSCHLAEGER, M., STROMINGER, J. L. & SPECK, S. H. (1989). Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes. Proceedings of the National Academv of Sciences, USA 86, 6498-6502.
21. WOISETSCHLAEGER, M., JlN, M. X-, YANDAVA, C. N., FURMANSKI, L. A., STROMINGER, J. L. & SPECK, S. H. (1991). Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection of B-lymphoctyes. Proceedings of the National Academy of Sciences, USA 88, 3942-3946.