Studies of tum- peptide analogs define an alternative anchor that can be utilized by Ld ligands lacking the consensus P2 anchor

Journal of Immunology

Volumn 156, Issue 11, 1996, Pages 4266-4273

  Robinson, Ruth A ^a   Lee, David R ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROLINE; TUMOR ANTIGEN;

ANTIGEN BINDING; ARTICLE; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; HISTOCOMPATIBILITY ANTIGENS; L CELLS (CELL LINE); LIGANDS; MICE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; VIRAL PROTEINS;

EID: 0029993109     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Townsend, A., and H. Bodmer. 1989. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:601.
2. Falk, K., O. Rötzschke, S. Stevanovic, O. Jung, and H.-G. Rammensee. 1991. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 351:290.
3. Bjorkman, P. J., M. A. Saper, B. Samraoui, W. S. Bennett, J. L. Strominger, and D. C. Wiley. 1987. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 329:512.
4. b. Science 257:919.
5. Garrett, T. P. J., M. A. Saper, P. J. Bjorkman, J. L. Strominger, and D. C. Wiley. 1989. Specificity pockets for the side chains of peptide antigens in HLA-AW68. Nature 342:692.
6. Jardelsky, T. S., W. S. Lane, R. A. Robinson, D. R. Madden, and D. C. Wiley. 1991. Identification of self-peptides bound to HLA-B27. Nature 353:326.
7. Madden, D. R., J. C. Gorga, J. L. Strominger, and D. C. Wiley. 1992. The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC. Cell 70:1035.
8. Matsumura, M., H. Fremont, P. A. Peterson, and I. A. Wilson. 1992. Emerging principles for the recognition of peptide antigens by MHC class 1 molecules. Science 257:927.
9. b at 2.4 Å resolution: implications for antigen-determinant selection. Cell 76:39.
10. Saper, M. A., and D. C. Wiley. 1991. Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution. J. Mol. Biol. 219:277.
11. s: sequence motif, quantitative binding and molecular modeling of the complex. J. Exp. Med. 176:1681.
12. d by cytolytic T cells. Cell 58:293.
13. + cytotoxic T lymphocytes in association with a class I MHC protein. Cell 69:989.
14. + T-cell clone. Proc. Natl. Acad. Sci. USA 90:11272.
15. - complexes. Int. Immunol. 6:1699.
16. Al-Ramadi, B. K., M. T. Jelonek, L. F. Boyd, D. H. Margulies, and A. L. M. Bothwell. 1995. Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR. J. Immunol. 155:662.
17. d-class 1 MHC molecule. Nature 344:439.
18. d serologic recognition. J. Immunol. 151:5387.
19. d antigen, the product of a third polymorphic locus of the mouse major histocompatibility complex. J. Immunol. 125: 2473.
20. Evans, G. A., D. H. Margulies, B. Shykind, J. G. Seidman, and K. Ozato. 1982. Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens. Nature 300:755.
21. 2m facilitates the folding of the α1 and α2 domains during de novo synthesis. J. Immunol. 140:3522.
22. d class I major histocompatibility complex molecules determines their antigenic structure. J. Exp. Med. 173:449.
23. Murre, C., E. Choi, J. Weiss, J. G. Seidman, K. Ozato, L. Lui, S. J. Burakoff, and C. S. Reiss. 1984. Dissection of serological and cytolytic T lymphocyte epitopes on murine major histocompatibility antigens by a recombinant H-2 gene separating the first two external domains. J. Exp. Med. 160:167.
24. Hämmerling, G. J., U. Hämmerling, and H. Lemke. 1979. Isolation of twelve monoclonal antibodies against Ia and H-2 antigens: serological characterization and reactivity of B and T lymphocytes. Immunogenetics 8:433.
25. Shiroishi, T., G. A. Evans, E. Appella, and K. Ozato. 1985. In vitro mutagenesis of a mouse MHC class I gene for the examination of structure-function relationships. J. Immunol. 134:623.
26. Ozato, K., N. Mayer, and D. H. Sachs. 1980. Hybridoma cell lines secreting monoclonal anybodies to mouse H-2 and Ia antigens. J. Immunol. 124:533.
27. Oi, V. T., P. P. Jones, J. W. Goding, and L. A. Herzenberg. 1978. Properties of monoclonal antibodies to mouse Ig allotypes, H-2, and Ia antigens. Curr. Top. Microbiol. Immunol. 81:115.
28. Reddehase, M. J., J. B. Rothbard, and U. H. Koszinowski. 1989. A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes. Nature 337:651.
29. Schultz, M., P. Aichele, M. Vollenweider, F. W. Bobe, F. Cardinaux, H. Hengartner, and R. M. Zinkemagel. 1989. Major histocompatibility complex-dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease. Eur. J. Immunol. 19:1657.
30. Oldstone, M. B. A., A. Tishon, R. Geckler, H. Lewicki, and J. L. Whitton. 1992. A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implications for vaccination. Proc. Natl. Acad. Sci. USA 89:2752.
31. Gavin, M. A., M. J. Gilbert, S. R. Riddell, P. D. Greenberg, and M. J. Bevan. 1993. Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I-restricted CTL epitopes. J. Immunol. 151:3971.
32. Townsend, A., C. Ohlen, J. Bastin, H.-G. Ljunggren, L. Foster, and K. Karre. 1989. Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 340:443.
33. w16 MHC class I molecule. Mol. Immunol. 31:943.
34. - mutation P35B generates the MHC-binding site of a new antigenic peptide. Immunogenetics 37:135.
35. 2-microglobulin. Proc. Natl. Acad. Sci. USA 89:7767.
36. Catipovic, B., J. Dal Porto, M. Mage, T. E. Johansen, and J. P. Schneck. 1992. Major histocompatibility complex conformational epitopes are peptide specific. J. Exp. Med. 176:1611.
37. Bluestone, J. A., S. Jameson, S. Miller, and R. Dick, II. 1992. Peptide-induced conformational changes in class I heavy chains alter major histocompatibility complex recognition. J. Exp. Med. 176:1757.
38. DiBrino, M., K. C. Parker, D. H. Margulies, J. Shiloach, R. V. Turner, W. E. Biddison, and J. E. Coligan. 1994. The HLA-B14 peptide binding site can accommodate peptides with different combinations of anchor residues. J. Biol. Chem. 269:32426.