Procaine microinjection into the lower midbrain increases brown fat and body temperatures in anesthetized rats

Brain Research

Volumn 716, Issue 1-2, 1996, Pages 171-179

  Shibata, Masaaki ^a   Iriki, Masami ^a   Arita, Jim ^a   Kiyohara, Toshikazu ^b   Nakashima, Toshihiro ^b   Miyata, Seiji ^b   Matsukawa, Takashi ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

indomethacin; interscapular brown adipose tissue; metabolic heat production; procaine; propranolol; temperature increase; tonic inhibition

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; INDOMETACIN; PROCAINE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; HISTOLOGY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; RAT; THERMOREGULATION;

EID: 0029993097     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00040-6     Document Type: Article

References (30)

1. Amini-Sereshki, L. and Zarrindast, M.R., Brainstem tonic inhibition of thermoregulation in the rat, Am. J. Physiol., 247 (1984) R154-R159.
2. Amini-Sereshki, L., Brainstem control of shivering in the cat. I. Inhibition, Am. J. Physiol., 232 (1977) R190-R197.
3. Amir, S., Shizgal, P. and Rompre, P.P., Glutamate injection into the suprachiasmatic nucleus stimulates brown fat thermogenesis in the rat, Brain Res., 498 (1989) 140-144.
4. Asami, T., Hori, T., Kiyohara, T. and Nakashima, T., Convergence of thermal signals on the reticulospinal neurons in the midbrain, pons and medulla oblongata, Brain Res. Bull., 20 (1988) 581-596.
5. Benzi, R.H., Shibata, M., Seydoux, J. and Girardier, L., Prepontine knife cut-induced hyperthermia in the rat, effect of chemical sympathectomy and surgical denervation of brown adipose tissue, Pflugers Arch., 411 (1988) 593-599.
6. 2 injected into the paraventricular nucleus of the hypothalamus on brown adipose tissue thermogenesis in spontaneously hypertensive rats, Brain Res., 613 (1993) 285-287.
7. Chambers, W.W., Seigel, M.S., Liu, J.C. and Liu, C.N., Thermoregulatory responses of decerebrate and spinal cats, Exp. Neurol., 42 (1974) 282-299.
8. Conner, J.D. and Crawford, I.L., Hyperthermia in mid-pontine lesioned cats, Brain Res., 15 (1969) 590-593.
9. Dib, B., Rompré, P.P., Amir, S. and Shizgal, P., Thermogenesis in brown adipose tissue is activated by electrical stimulation of the rat dorsal raphe nucleus, Brain Res., 650 (1994) 149-152.
10. Girardier, L. and Seydoux, J., Neural control of brown adipose tissue. In P. Trayhurn and D.G. Nicholls (Eds.), Brown Adipose Tissue, Edward Arnold, London, 1986, pp. 122-151.
11. Gronert, G.A. and Antognini, J.F., Malignant hyperthermia. In R.D. Miller (Ed.), Anesthesia, Vol. 1, Chuchill Livingstone, NY, 1994, pp. 1075-1093.
12. Haggendal, J., Jonsson, L. and Carlsten, J., The role of sympathetic activity in intiating malignant hyperthermia, Acta Anaesthesiol. Scand., 34 (1990) 677-682.
13. Hashimoto, M., Characterization and mechanism of fever induction by interleukin-1 beta, Pflugers Arch., 419 (1991) 616-621.
14. Iaizzo, P.A. and Wedel, D.J., Response to succinylcholine in porcine malignant hyperthermia, Anesth. Analg., 79 (1994) 143-151.
15. Jessen, K. and Rosendal, T., Hyperthermia under anaesthesia, Nord. Med., 86 (1971) 1001-1004.
16. Kitanaka, C., Inoh, Y., Toyoda, T., Sasaki, T. and Eguchi, T., Malignant brainstem hyperthermia caused by brainstem hemorrhage, Stroke, 25 (1994) 518-520.
17. Liu, J.C., Tonic inhibition of thermoregulation in the decerebrate monkey (Saimiri sciureus), Exp. Neurol., 64 (1979) 632-648.
18. Moragas, A. and Toran, N., Brown adipose tissue changes in anencephalic infants: image analysis study, Path. Res. Pract., 180 (1985) 207-210.
19. 2 receptor agonist talipexole in the rat, Pharmacol. Biochem. Behav., 43 (1992) 993-997.
20. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, Florida, 1986.
21. Quan, N. and Blatteis, C.M., Microdialysis: a system for localized drug delivery into the brain, Brain Res. Bull., 22 (1989) 621-625.
22. Rothwell, N.J., Stock, M.J. and Thexton, A.J., Decerebration activates thermogenesis in the rat, J. Physiol. (Lond.), 342 (1983) 15-22.
23. Seydoux, J., Benzi, R.H., Shibata, M. and Girardier, L., Underlying mechanisms of the atrophic state of brown adipose tissue in obese Zucker rats, Am. J. Physiol., 259 (1990) R61-R69.
24. Shibata, M., Benzi, R.H., Seydoux, J. and Girardier, L., Hyperthermia induced by pre-pontine knife-cut: evidence for a tonic inhibition of nonshivering thermogenesis in anesthetized rat, Brain Res., 436 (1987) 273-282.
25. Shibata, M., Hori, T. and Nagasaka, T., Effects of single cortical spreading depression on metabolic heat production in the rat, Physiol. Behav., 34 (1985) 565-567.
26. Shibata, M., Hori, T., Kiyohara, T. and Nakashima, T., Activity of hypothalamic thermosensitive neurons during cortical spreading depression in the rat, Brain Res., 308 (1984) 255-262.
27. Shibata, M., Leffler, C.W. and Busija, D.W., Prostanoids attenuate pial arteriolar dilation induced by cortical spreading depression in rabbits, Am. J. Physiol., 261 (1991) R828-R834.
28. Thornhill, J., Jugnauth, A. and Halvorson, I., Brown adipose tissue thermogenesis by medial preoptic stimulation is mediated via the ventromedial hypothalamic nucleus, Can. J. Physiol. Pharmacol., 72 (1994) 1042-1048.
29. Verburg, M.P., Oerlemans, F.T.J.J., Van Bennekom, C.A., Gielen, M.J.M, De Bruyn, C.H.M.M. and Crul, J.F., In vivo induced malignant hyperthermia in pigs. I. physiological and biochemical changes and the influence of dantrolene sodium, Acta Anaesthesiol. Scand., 28 (1984) 1-8.
30. Woods, A.J. and Stock, M.J., Biphasic brown fat temperature responses to hypothalamic stimulation in rats, Am. J. Physiol., 266 (1994) R328-R337.