Precolumn fluorescence derivatization of the antagonist [Arg6,D-Trp7,9,MePhe8]-substance P{6-11} with benzoin in high-performance liquid chromatography and selective detection of arginine-containing fragments in its degradation products

Journal of Chromatography A

Volumn 736, Issue 1-2, 1996, Pages 91-96

  Hua, Cui ^a,b   Reubsaet, J Leon E ^a   Bult, Auke ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Amino acids; Antagonist G; Arginine; Benzoin; Derivatization, LC; Peptides; Pharmaceutical analysis

Indexed keywords

SUBSTANCE P [6 ARGININE 7,9 DEXTRO TRYPTOPHAN 8 (4 METHYLPHENYLALALINE)]; SUBSTANCE P ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; DERIVATIZATION; DRUG DEGRADATION; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN ANALYSIS; TECHNIQUE;

AMINO ACID SEQUENCE; ARGININE; BENZOIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUORESCENT DYES; INDICATORS AND REAGENTS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTANCE P;

EID: 0029992921     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9673(95)01359-8     Document Type: Article

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