The prejunctional inhibitory effect of suramin on neuromuscular transmission in vitro

European Journal of Pharmacology

Volumn 301, Issue 1-3, 1996, Pages 91-97

  Henning, Robert H ^a   Rowan, Edward G ^b   Braga, M Fatima M ^b   Nelemans, Adriaan ^a   Harvey, Alan L ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Ca2+ channel; Neuromuscular transmission; Non depolarizing neuromuscular relaxant; P2 purinoceptor; Suramin

Indexed keywords

3,4 DIAMINOPYRIDINE; ACETYLCHOLINE; ADENOSINE; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); CALCIUM CHANNEL; CALCIUM ION; CHOLINE; ERABUTOXIN; MAGNESIUM ION; NEUROMUSCULAR BLOCKING AGENT; PURINE P2 RECEPTOR; PURINE P2 RECEPTOR ANTAGONIST; RADIOISOTOPE; SURAMIN; TETRYLAMMONIUM; TUBOCURARINE CHLORIDE; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIAPHRAGM; DRUG ANTAGONISM; DRUG MECHANISM; ENDPLATE POTENTIAL; MALE; MEMBRANE CURRENT; MINIATURE ENDPLATE POTENTIAL; MOUSE; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR TRANSMISSION; NONHUMAN; PARALYSIS; PHRENIC NERVE; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; RAT; SODIUM CURRENT;

EID: 0029992807     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00065-9     Document Type: Article

References (32)

1. + channels, on motor nerve terminals, Br. J. Pharmacol. 95, 1299.
2. Braga, M.F.M., E.G. Rowan and A.L. Harvey, 1991, Effects of tacrine, velnacrine (HP029), suronacrine (HP128), and 3,4-diaminopyridine on skeletal neuromuscular transmission in vitro, Br. J. Pharmacol. 102, 909.
3. Carlson B.J. and M.A. Raftery, 1993, Specific binding of ATP to extracellular sites on Torpedo acetylcholine receptor. Biochemistry 32, 7329.
4. Correia-de-Sá, P., A.M. Sebastião and J.A. Ribeiro, 1991, Inhibitory and excitatory effects of adenosine receptor agonists on evoked transmitter release from phrenic nerve endings of the rat, Br. J. Pharmacol. 103, 1614.
5. 2+ level accompanying initial nerve-muscle contact in tissue culture. Neuron 10, 827.
6. Den Hertog, A., J. Van den Akker and S.A. Nelemans, 1989, Suramin and the inhibitory junction potential in taenia caeci of the guinea-pig, Eur. J. Pharmacol. 173, 207.
7. 2 purinoceptor antagonist in mouse vas deferens, Br. J. Pharmacol. 93, 243.
8. 2 purinoceptor-stimulated phosphoinositide turnover in chick myotubes, FEBS Lett. 235, 133.
9. Hamilton, B.R. and D.O. Smith, 1991, Autoreceptor-mediated purinergic and cholinergic inhibition of motor nerve terminal calcium currents in the rat, J. Physiol. (London) 432, 327.
10. Henning, R.H., S.A. Nelemans, J. Van den Akker and A. Den Hertog, 1992a. The nucleotide receptors on mouse C2C12 myotubes, Br. J. Pharmacol. 106, 853.
11. Henning, R.H., S.A. Nelemans, A.H.J. Scaf, J. Van Eekeren, S. Agoston and A. Den Hertog, 1992b, Suramin reverses non-depolarizing neuromuscular blockade in rat diaphragm, Eur. J. Pharmacol. 216, 73.
12. 2 purinoceptors in C2C12 myotubes. Br. J. Pharmacol. 110, 747.
13. Henning, R.H., M.C. Houwertjes, S.A. Nelemans and S. Agoston, 1993b, Reversal by suramin of neuromuscular block produced by pancuronium in the anaesthetized rat, Br. J. Pharmacol. 108, 717.
14. 2 purinoceptor mediated cyclic AMP formation in mouse C2C12 myotubes, Br. J. Pharmacol. 110, 133.
15. Hourani, S.M.O. and J.A. Chown, 1989, The effects of some possible inhibitors of ectonucleotidases on the breakdown and pharmacological effects of ATP in the guinea pig urinary bladder, Gen. Pharmacol. 20, 177.
16. 2 purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli, Br. J. Pharmacol. 99, 617.
17. Kolb, H.A. and M.J.O. Wakelam, 1983, Transmitter-like action of ATP on patched membranes of cultured myoblasts and myotubes, Nature 303, 621.
18. 2 receptors in rabbit isolated ear artery, Br. J. Pharmacol. 101, 645.
19. Mallart, A., 1985, Electric current flow inside perineurial sheats of mouse motor nerves, J. Physiol. (London) 368, 565.
20. Nakazawa K., K. Fujimori, A., Takanaka and K. Inoue, 1991, Reversible and selective antagonism by suramin of ATP-activated inward current in PC12 phaeochromocytoma cells, Br. J. Pharmacol. 102, 581.
21. Penner, R. and F. Dreyer, 1986, Two different presynaptic calcium currents in mouse motor nerve terminals, Pflügers Arch. 406, 190.
22. Pillet, L., O. Tremeau, F. Ducancel, P. Drevet, S. Zinn-Justin, S. Pinkasfeld, J.C. Boulain and A. Menez, 1993, Genetic engineering of snake toxins. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis, J. Biol. Chem. 268, 909.
23. Ribeiro, J.A. and J. Walker, 1975, The effect of adenosine triphosphate and adenosine diphosphate on transmission at the rat and frog neuromuscular junctions. Br. J. Pharmacol. 54, 213.
24. Silinsky, E.M. and J.I. Hubbard, 1973. Release of ATP from rat motor nerve terminals, Nature 243, 404.
25. Silinsky, E.M., C. Solsona and J.K. Hirsh, 1989, Pertussis toxin prevents the inhibitory effect of adenosine and unmasks adenosine-induced excitation at mammalian motor nerve endings, Br. J. Pharmacol. 97, 16.
26. Smith, D.O., 1991, Sources of adenosine released during neuromuscular transmission in the rat. J. Physiol. (London) 432, 343.
27. 2--ATPase as a membrane ecto-enzym of human granulocytes: Inhibitors, activators and response to phagocytosis, Biochim. Biophys. Acta 512, 525.
28. Uchitel, O.D., D.A. Protti, V. Sanchez, B.D. Cherksey, M. Sugimori and R. Llinas, 1992, P-type voltage-dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses, Proc. Natl. Acad. Sci. USA 89, 3330.
29. Volknandt, W. and H. Zimmerman, 1986, Acetylcholine, ATP, and proteoglycan are common to synaptic vesicals isolated from the electric organs of eel and electric catfish as well as from rat diahragm, J. Neurochem. 47, 1449.
30. Wagner, J.A., S.S. Carlson and R.B. Kelly, 1978, Chemical and physical characterization of cholinergic synaptic vesicels, Biochemistry 17, 1199.
31. Webb, T.E., J. Simon, B.J., Krishek, A.N. Bateson, T.G. Smart, B.F. King, G. Burnstock and E.A. Barnard, 1993, Cloning and functional expression of a brain G-protein-coupled ATP receptor, FEBS Lett. 324, 219.
32. 3H]acetylcholine from a modified rat phrenic nerve-hemidiaphragm preparation, Naunyn-Schmied. Arch. Pharmacol. 334, 357.