Detection of transforming growth factor-β in sputum from patients with bronchial asthma by eosinophil survival assay and enzyme-linked immunosorbent assay

Clinical and Experimental Allergy

Volumn 26, Issue 5, 1996, Pages 557-562

  Adachi, T ^a   Motojima, S ^b,c   Hirata, A ^b   Fukuda, T ^b   Kihara, N ^a   Makino, S ^b  

^a Kihara Hospital   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

^c Dokkyo Univ Shchool of Medicine   (Japan)

Author keywords

Bronchial asthma; Enzyme linked immunosorbent assay; Eosinophil; Granulocyte macrophage colony stimulating factor; Guinea pig; Interleukin 5; Sputum; Transforming growth factor B

Indexed keywords

INTERLEUKIN 5; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; FEMALE; GUINEA PIG; HUMAN; MALE; PRIORITY JOURNAL; SPUTUM;

ADULT; AGED; ANIMALS; ANTIBODIES, MONOCLONAL; ASTHMA; CELL SURVIVAL; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EOSINOPHILS; FEMALE; GUINEA PIGS; HUMANS; INTERLEUKIN-5; MALE; MIDDLE AGED; SPUTUM; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029992438     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.1996.tb00576.x     Document Type: Article

References (36)

1. Gleich GJ. The eosinophil and bronchial asthma: Current understanding. J Allergy Clin Immunol 1990; 85:422-36.
2. Yamaguchi Y, Hayashi Y, Sugama Y et al. Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. J Exp Med 1988; 167:1737-42.
3. Lopez AF, Williamson J, Gamble JR et al. Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. J Clin Invest 1986; 78:1220-8.
4. Rothenberg ME, Owen WF, Silberstein DS et al. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest 1988; 81:1986-92.
5. Adachi T, Motojima S, Hirata A, Fukuda T, Makino S. Eosinophil viability-enhancing activity in sputum from patients with bronchial asthma: contributions of interleukin-5 and granulocyte-macrophage colony-stimulating factor. Am J Respir Crit Care Med 1995; 151:618-23.
6. Border WA, Ruoslahti E. Tranforming growth factor-b in disease: the dark side of tissue repair. J Clin Invest 1992; 90:1-7.
7. Kehrl JH, Wakefield LM, Roberts AB et al. Production of transforming growth factor b by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med 1986; 163:1037-50.
8. Tsunawaki S, Sporn M, Ding A, Nathan C. Deactivation of macrophages by transforming growth factor-b. Nature 1988; 334:260-2.
9. Gamble JR, Vadas MA. Endothelial cell adhesiveness for human T lymphocytes is inhibited by transforming growth factor-b1. J Immunol 1991; 146:1149-54.
10. Alam R, Forsythe P, Stafford S, Fukuda Y. Transforming growth factor b abrogates the effects of hematopoietins on eosinophils and induces their apoptosis. J Exp Med 1994; 179:1041-5.
11. Atsuta J, Fujisawa T, Iguchi K, Terada A. Inhibitory effect of TGF-b1 on cytokine-enhanced eosinophil survival. Jpn J Allergol 1994; 43:1194-200.
12. Adachi T, Motojima S, Hirata A et al. Guinea pig eosinophils possess receptors capable of binding to human interleukin-5 and human granulocyte/macrophage colony-stimulating factor. Dokkyo J Med Sci 1995; 22:171-7.
13. Wong DTW, Donoff RB, Yang J et al. Sequential expression of transforming growth factors a and b1 by eosinophils during cutaneous wound healing in the hamster. Am J Pathol 1993; 143:130-42.
14. Obberghen-Schilling EV, Roche NS, Flanders KC, Sporn MB, Roberts AB. Transforming growth factor b1 positively regulates its own expression in normal and transformed cells. J Biol Chem 1988; 263:7741-6.
15. Elovic A, Wong DTW, Weller PF, Matossian K, Galli SJ. Expression of transforming growth factors-a and b1 messenger RNA and product by eosinophils in nasal polyps. J Allergy Clin Immunol 1994; 93:864-9.
16. Romberger DJ, Beckmann JD, Claassen L, Ertl RF, Rennard SI. Modulation of fibronectin production of bovine bronchial epithelial cells by transforming growth factor-b. Am J Respir Cell Mol Biol 1992; 7:149-55.
17. Yamaguchi Y, Suda T, Ohta S et al. Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils. Blood 1991; 78:2542-7.
18. Takatsu K, Takaki S, Hitoshi Y. Interleukin-5 and its receptor system: implications in the immune system and inflammation. Adv Immunol 1994; 57:145-90.
19. Sakamaki K, Miyajima I, Kitamura T, Miyajima A. Critical cytoplasmic domains of the common b subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J 1992; 11:3541-9.
20. Duronio V, Clark LI, Federsppiel B, Wieler JS, Schrader JW. Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor. J Biol Chem 1992; 267:21856-63.
21. Mui AL, Cutler RL, Alai M et al. Steel factor and interleukin-3 stimulate the tyrosine phosphorylation of p95Vav in hematopoietic cell lines. Exp Hematol 1992; 20:752.
22. Hanazono Y, Chiba S, Sasaki K et al. c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor. EMBO J 1993; 12:1641-6.
23. Sato N, Sakamaki K, Terada N, Arai K, Miyajima A. Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common b subunit responsible for different signaling. EMBO J 1993; 12:4181-9.
24. Torigoe T, O'Connor R, Santoli D, Reed JC. Interleukin-3 regulates the activity of the Lyn protein-tyrosine kinase in myeloid-committed leukemic cell lines. Blood 1992; 80:617-24.
25. Pazdrak K, Schreiber D, Forsythe P, Justement L, Alam R. The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of Lyn tyrosine kinase and the Ras-Raf I-MEK-microtubule-associated protein kinase pathway. J Exp Med 1995; 181:1827-34.
26. c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region. Mol Cell Biol 1994; 14:4335-41.
27. Pazdrak K, Stafford S, Alam R. The activation of the Jak-STAT 1 signaling pathway by IL-5 in eosinophils. J Immunol 1995; 155:397-402.
28. Pazdrak K, Justement L, Alam R. Mechanism of inhibition of eosinophil activation by transforming growth factor-b: inhibition of Lyn, MAP, Jak 2 kinases and STAT 1 nuclear factor. J Immunol 1995; 155:4454-8.
29. Miyazono K, Hellman U, Wernstedt C, Heldin C-H. Latent high molecular weight complex of transforming growth factor b1. J Biol Chem 1988; 263:6407-15.
30. Lyons RM, Keski-Oja J, Moses HL. Proteolytic activation of latent transforming growth factor-b from tibroblast-conditioned medium. J Cell Biol 1988; 106:1659-65.
31. Miyazono K, Heldin C-H. Role for carbohydrate structures in TGF-b1 latency. Nature 1989; 338:158-60.
32. Grotendorst GR, Smale G, Pencev D. Production of transforming growth factor b by human peripheral blood monocytes and neutrophils. J Cell Physiol 1989; 140:396-402.
33. Sato Y, Rifkin DB. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-b1-like molecule by plasmin during co-culture. J Cell Biol 1989; 109:309-15.
34. Sacco O, Romberger D, Rizzino A et al. Spontaneous production of transforming growth factor-b2 by primary cultures of bronchial epithelial cells. J Clin Invest 1992; 90:1379-85.
35. Aubert J-D, Dalal BI, Bai TR et al. Transforming growth factor b1 gene expression in human airways. Thorax 1994; 49:225-32.
36. Wong DTW, Elovic A, Matossian K et al. Eosinophils from patients with blood eosinophilia express transforming growth factor b1. Blood 1991; 78:2702-7.