Mechanisms of loss of HLA class I expression on colorectal tumor cells

Tissue Antigens

Volumn 47, Issue 5, 1996, Pages 364-371

  Browning, M ^a,d   Petronzelli, F ^b   Bicknell, D ^a   Krausa, P ^a   Rowan, A ^c   Tonks, S ^b   Murray, N ^a   Bodmer, J ^a,b   Bodmer, W ^a,c  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c Cancer Genetics Laboratory   (United Kingdom)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Colorectal tumor cells; HLA class I expression

Indexed keywords

BETA 2 MICROGLOBULIN; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN HEAVY CHAIN;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; GENE MUTATION; HLA SYSTEM; IMMUNOGLOBULIN GENE; PRIORITY JOURNAL; TUMOR CELL LINE; TUMOR IMMUNITY;

EID: 0029992407     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.1996.tb02571.x     Document Type: Article

References (38)

1. Townsend A, Rothbard J, Gotch F, Bahadur B, Wraith D, McMichael A. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 1986: 44: 959-68.
2. Boon T, de Plaen E, Lurquin C et al. Identification of tumor rejection antigens recognised by T lymphocytes. Cancer Surveys 1992: 13: 23-52.
3. Brodsky FM, Parham P, Barnstable CJ, Crumpton MJ, Bodmer WF. Monoclonal antibodies for analysis of the HLA system. Immunol Rev 1979: 47: 3-61.
4. Fleming KA, McMichael A, Morton JA, Woods J, McGee J. Distribution of HLA-class I antigens in normal human tissue and in mammary cancer. J Clin Pathol 1981: 34: 779-84.
5. Kabawat S, Bast RJ, Welch W, Knapp R, Bhan A. Expression of major histocompatibility antigens and nature of inflammatory cellular infiltrate in ovarian neoplasms. Int J Cancer 1983: 32: 547-55.
6. Doyle A, Martin J, Funa K et al. Markedly decreased expression of class I histocompatibility antigens, protein and mRNA in human small-cell lung cancer. J Exp Med 1985: 161: 1135-51.
7. Smith MEF, Marsh SGE, Bodmer JG, Gelsthorpe K, Bodmer WF. Loss of HLA-A, B, C allele products and lymphocyte function-associated antigen 3 in colorectal neoplasia. Proc Natl Acad Sci U S A 1989: 86: 5557-61.
8. Pandolfi F, Boyle LA, Trentin L, Kurnick JT, Isselbacher KJ, Gattoni-Celli S. Expression of HLA-A2 antigen in human melanoma cell lines and its role in T cell recognition. Cancer Res 1991: 51: 3164-70.
9. Garrido F, Cabrera T, Concha A, Glew S, Ruiz-Cabello F, Stern P. Natural history of HLA expression during tumour development. Immunol Today 1993: 14: 491-9.
10. Bodmer WF, Browning MJ, Krausa P, Rowan A, Bicknell DC, Bodmer JG. Tumor escape from immune response by variation in HLA expression and other mechanisms. Ann N Y Acad Sci 1993: 690: 42-9.
11. Kaklamanis L, Gatter K, Hill AB et al. Loss of HLA class I alleles, heavy chains and β2-microglobulin in colorectal cancer. Int J Cancer 1992: 51: 1-7.
12. Barnstable CJ, Bodmer WF, Brown G et al. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens. Cell 1978: 14: 9-20.
13. Smith M, Bodmer W, Bodmer J. Selective loss of HLA-A, B, C locus products in colorectal adenocarcinoma. Lancet 1988: 1: 823-4.
14. Wang P, Vanky F, Li SL, Vegh Z, Persson U, Klein E. Expression of MHC class I antigens on human carcinomas and sarcomas analysed by iso-electric focusing. Int J Cancer 1991: 6(suppl): 106-16.
15. Moller P, Koretz K, Schlag P, Momburg F. Frequency of abnormal expression of HLA-A, B, C and HLA-DR molecules, invariant chain and LFA-3 (CD58) in colorectal carcinoma and its impact on tumor recurrence. Int J Cancer 1991: 6(suppl): 155-62.
16. Bicknell DC, Rowan A, Bodmer WF. β2-microglobulin mutations: a study of established colorectal cell lines and fresh tumors. Proc Natl Acad Sci U S A 1994: 91: 4751-5.
17. Browning MJ, Krausa P, Rowan A, Bicknell DC, Bodmer JG, Bodmer WF. Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines. Proc Natl Acad Sci U S A 1993: 90: 2842-5.
18. Krausa P, Bodmer JG, Browning MJ. Defining the common subtypes of HLA-A9, A10, A28 and A19 by use of ARMS PCR. Tissue Antigens 1993: 43: 91-9.
19. Sadler AM, Petronzelli F Krausa P et al. Low resolution DNA typing for HLA-B using sequence specific primers in allele or group specific ARMS PCR. Tissue Antigens 1994: 44: 148-54.
20. Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence specific primers (SSP-PCR) in two hours: and alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992: 39: 225-35.
21. Durbin H, Bodmer WF. A sensitive micro-immunoassay using β-galactosidase/anti-β-galactosidase complexes. J Immunol Meth 1987: 97: 19-27.
22. Lampson LA, Fisher CA, Whelan JP. Striking paucity of HLA-A,B,C and β2-microglobulin on human neuroblastoma cell lines. J Immunol 1983: 130: 2471-8.
23. Bodmer WF. The HLA system: structure and function. J Clin Pathol 1987: 40: 948-58.
24. Kaklamanis L, Townsend A, Doussis-Anagnostopoulou IA, Mortensen N, Harris AL, Gatter KC. Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer. Am J Pathol 1994: 145: 505-9.
25. Browning MJ, Krausa P, Rowan A et al. Loss of human leukocyte antigen expression on colorectal tumor cell lines: implications for anti-tumour immunity and immunotherapy. J Immunother 1993: 14: 163-8.
26. Smith MEF, Bodmer JG, Kelly AP, Trowsdale J, Kirkland SC, Bodmer WF. Variation in HLA expression on tumours: an escape from immune response. Cold Spring Harbor Symp Quant Biol 1989: 54: 581-6.
27. Salter RD, Cresswell P. Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO J 1986: 5: 943-9.
28. Rosa F, Berissi H, Weissenbach J, Maroteaux L, Fellous M, Revel M. The β2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon. EMBO J 1983: 2: 239-43.
29. d'Urso CM, Wang Z, Cao Y, Tatake R, Zeff RA, Ferrone S. Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in β2m gene expression. J Clin Invest 1991: 87: 284-92.
30. Marincola FM, Shamamian P, Alexander RB et al. Loss of HLA haplotype and B locus down-regulation in melanoma cell lines. J Immunol 1994: 153: 1225-37.
31. Ruiz-Cabello F, Perez-Ayala M, Redondo M, Concha A, Cabrera T, Garrido F. Molecular analysis of MHC class I alterations in human tumour cell lines. Int J Cancer 1991: 6(suppl): 123-30.
32. Restifo NP, Esquivel F, Kawakami Y et al. Identification of human cancers deficient in antigen processing. J Exp Med 1993: 177: 265-72.
33. Cromme FV, Airey J, Heemels M-T et al. Loss of transporter protein encoded by the TAP-1 gene is highly correlated with loss of HLA expression in cervical carcinomas. J Exp Med 1994: 179: 335-40.
34. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colon carcinogenesis. Nature 1993: 363: 558-61.
35. Peltomaki Aaltonen LA, Sistonen P et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science 1993: 260: 810-12.
36. Aaltonen LA, Peltomaki P, Leach FS et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993: 260: 812-16.
37. Branch P, Rowan A, Bicknell DC, Bodmer WF, Karran P. Immune surveillance in colorectal carcinoma. Nature Genet 1995: 9: 231-2.
38. Duggan-Keen MF, Keating PJ, Stevens FRA et al. Immunogenetic factors in HPV associated cervical cancer: influence on disease progression. Eur J Immunogenet (in press).