Efficient tumor eradication by adoptively transferred cytotoxic T-cell clones in allogeneic hosts

International Journal of Cancer

Volumn 66, Issue 5, 1996, Pages 686-691

  Toes, René E M ^a   Kast, W Martin ^a   Blom, Ria J J ^a   Bakker, Steven C ^a   Offringa, Rienk ^a   Melief, Cornelis J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RECOMBINANT INTERLEUKIN 2;

ADENOVIRUS; ADOPTIVE TRANSFER; ALLOIMMUNITY; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER; CANCER IMMUNOTHERAPY; CELL MEDIATED CYTOTOXICITY; CLONE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EMBRYO; H2 RESTRICTION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; VASCULAR ENDOTHELIUM; VIRUS CARCINOGENESIS;

AMINO ACID SEQUENCE; ANIMALS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOTHERAPY, ADOPTIVE; MICE; MICE, INBRED C57BL; MICE, NUDE; MOLECULAR SEQUENCE DATA; NEOPLASMS, EXPERIMENTAL; POLYMORPHISM, GENETIC; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0029992369     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960529)66:5<686::AID-IJC17>3.0.CO;2-2     Document Type: Article

References (30)

1. ANDO, K., GUIDOTTI, L.G., CERNY, A., ISHIKAWA, T. and CHISARI. F., CTL access to tissue antigen is restricted in vivo J. Immunol., 153, 482-488 (1994).
2. BUTTURINE, A., BORTIN, M.M. and GALE, R.P., Graft-versus leukemia following bone marrow transplantation. Bone Marrow Transplant., 2, 233-236 (1987).
3. DOHERTY, P.C. and ALLEN, J.E., Role of the major histocompatibiliry complex in targeting effector T cells into a site of virus infection. Europ. J. Immunol., 16, 1237-1242 (1986).
4. + T cells. Immunol. Today, 11, 55-59 (1990).
5. DOHERTY, P.C., CEREDIG, R. and ALLEN, J.E., Immunogenetic analysis of cellular interactions governing the recruitment of T lymphocytes and monocytes in lymphocytic choriomeningitis virus-induced immunopathology. Clin. Immunol. Immunopathol., 47, 19-26 (1988).
6. FABER, L.M., VAN LUXEMBURG-HEIJS, S.A.P., WILLEMZE, R. and FALKENBURG, J.H.F., Generation of leukemia-reactive cytotoxic T lymphocyte clones from the HLA-identical bone marrow donor of a patient with leukemia. J. exp. Med., 176, 1283-1289 (1992).
7. FALK, K., RÖTZSCHKE, O., STEVANOVIC, S., JUNG, G. and RAMMENSEE, H.-G., Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature (Lond.), 351, 290-296 (1991).
8. FELTKAMP, M.C.W., SMITS, H.L., VIERBOOM, M.P.M., MINNAAR, R.P., DE JONGH, B.M., DRIJFHOUT, J.W., TER SCHEGGET, J., MELIEF, C.J.M. and KAST, W.M., Vaccination with cytotoxic T lymphocyte epitopecontaining peptide protects against a tumor induced by human papillomavirus type 16-transformed cells. Europ. J. Immunol., 23, 2242-2249 (1993).
9. FISHER, B., PACKARD, B.S. READ, E.J., CARRASQUILLO, J.A., CARTER, C.S., TOPALIAN, S.L., YANG, J.Y., YOLLES, P., LARSON, S.M. and ROSENBERG, S.A., Tumor localization of adoptively transferred indium-111 labeled tumor infiltrating lymphocytes in patients with metastatic melanoma. J. clin. Oncol., 7, 250-261 (1989).
10. FOUROUET, A., TEILLAUD, J.L., LANDO, D. and FRIDMAN, W.H., Effects of low dose total body irradiation (LDTBI) and recombinant human interleukin-2 in mice. Radiother. Oncol., 26, 219-225 (1993).
11. GALE, R.P. and CHAMPLIN, R.E., How does bone marrow transplantation cure leukemia? Lancet, 2, 28-30 (1984).
12. GIRARD, J.-P. and SPRINGER, T.A., High endothelial venules (HEVs): specialized endothelium for lymphocyte migration. Immunol. Today, 16, 449-456 (1995).
13. GOUSEPOHL, H., KRAFT, M., BOULIN, CH. and FRANK, R.W., Automated multiple peptide synthesis with BOP activation. In: J.E. Rivier and G.R. Manshall (eds.), Proc. 11th American peptide symposium, p. 1003, ESCOM, Leiden (1990).
14. GREENBERG, P.D., Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells. Adv. Immunol., 49, 280-355 (1991).
15. HAMANN, A. and THIELE, H.G., Molecules and regulation in lymphocyte migration. Immunol. Rev., 108, 19-44 (1989).
16. b mutants are generated by genetic microrecombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness. J. exp. Med., 168, 2319-2335 (1988).
17. HOGG, N. and BERLIN, C., Structure and function of adhesion receptors in leukocyte trafficking. Immunol. Today, 16, 327-330 (1995).
18. KAST, W.M., OFFRINGA, R , PETERS, P.J., VOORDOUW, A., MELOEN, R.H., VAN DER EB, A.J. and MELIEF, C.J.M., Eradication of adenovirus E1-induced tumors by E1A-specific cytotoxic T lymphocytes. Cell, 59, 603-615 (1989).
19. KENNEDY, J.D., PIERCE, C.W. and LAKE, J.P., Extrathymic T cell maturation; phenotypic analysis of T cell subsets in nude mice as function of age. J. Immunol., 148, 1620-1628 (1992).
20. KOLB, H.J., MITTELMULLER, J., CLEMM, C., HOLLER, E., LEDDEROSE, G., BREHM, G., HEIM, M. and WILLMANNS, W., Donor leucocyte transfusions for treatment of recurrent chronic myelogenous leukemia in bone marrow transplant patients. Blood, 76, 2462-2465 (1990).
21. MARTIN, P.J., HANSEN, R., STORB, R. and THOMAS, E.D., Human marrow transplantation, an immunological perspective. Adv. Immunol., 40, 379-384 (1987).
22. MELIEF, C.J.M., Tumor eradication by adoptive transfer of cytotoxic T lymphocytes. Adv. Cancer Res., 58, 143-175 (1992).
23. b haplotype reveal genetic control of isotype expression. J. Immunol., 126, 317-321 (1981).
24. PABST, R. and BINNS, R.M., Heterogeneity of lymphocyte homing physiology: several mechanisms operate in the control of migration to lymphoid and non-lymphoid organs in vivo. Immunol. Rev., 108, 83-109 (1989).
25. ROSENSTEIN, M., ETTINGHAUSEN, S.E. and ROSENBERG, S.A., Extravasation of intiavascular fluid mediated by the systemic administration of recombinant interleukin 2. J. Immunol., 137, 1735-1742 (1986).
26. TOES, R.E.M., DEN HAAN, J.M.M., FELTKAMP, M.C.W., BLOM, R.J.J., MELIEF, C.J.M., CLAASSEN, E. and KAST, W.M., In vivo detection of fluorescent tumor-specific cytotoxic T cells J. Immunol. Meth., 163, 23-32 (1993).
27. TOES, R.E.M., OFFRINGA, R., BLOM, R.J.J., BRANDT, R.M.P., VAN DER EB, A.J., MELIEF, C.J.M. and KAST, W.M., An adenovirus type 5 early region 1B-encoded CTL epitope mediating tumor eradication by CTL clones is down-modulated by an activated ras oncogene. J. Immunol., 154, 3396-3405 (1995).
28. TOES, R.E.M., OFFRINGA, R., FELTKAMP, M.C.W., VISSEREN, M.J.W., SCHOENBERGER, S.P., MELIEF, C.J.M. and KAST, W.M., Tumor rejection antigens and tumor specific cytotoxic T lymphocytes. Behring Inst. Mitt., 94, 72-86 (1994).
29. TRAVERSARI, C.P., VAN DER BRUGGEN, P., VAN DEN EYNDE, B., HAINALT, P., LEMOINE, C., OHTA, N., OLD, L. and BOON, T., Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes. Immunogenet, 35, 145-152 (1992).
30. b at 2.4 A resolution: implication for antigen-determinant selection. Cell, 76, 39-50 (1994).