In vitro release test system of (D,L-lactic-glycolic) acid copolymer microcapsules for sustained release of LHRH agonist (leuprorelin)

Journal of Controlled Release

Volumn 40, Issue 3, 1996, Pages 269-276

  Kamijo, Akiko ^a   Kamei, Shigeru ^a   Saikawa, Akira ^a   Igari, Yasutaka ^a   Ogawa, Yasuaki ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Injectable microcapsules; Matrix degradation; PLGA; Release test

Indexed keywords

COPOLYMER; GLYCOLIC ACID; LACTIC ACID; LEUPRORELIN;

ARTICLE; BIODEGRADATION; CHEMICAL STRUCTURE; DRUG ANALYSIS; DRUG DEVELOPMENT; DRUG RELEASE; MICROCAPSULE; OSMOLARITY; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; WEIGHT REDUCTION;

EID: 0029992322     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00194-8     Document Type: Article

References (17)

1. Y. Ogawa, M. Yamamoto, H. Okada, T. Yashiki and T. Shimamoto, A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copolydactic/glycolic) acid, Chem. Pharm. Bull. 36 (1988) 1095-1103.
2. H. Okada, Y. Doken, Y. Ogawa and H. Toguchi, Preparation of three-month depot, Injectable microspheres of leuprorelin acetate using biodegradable polymers, Pharm. Res. 11 (1994) 1143-1147.
3. 6] luteinizing hormone-releasing hormone from injectable microcapsules, Proc. Natl. Acad. Sci. USA 81 (1984) 5845-5848.
4. M. Mason-Garcia. M. Vaccarella, J. Horvath, T.W. Redding, K. Groot, P. Orsolini and A.V. Schally, Radioimmunoassay for octapeptide analogs of somatostatin: measurement of serum levels after administration of long-acting microcapsule formulations, Proc. Natl. Acad. Sci. USA 85 (1988) 5688-5692.
5. I. Heron, F. Thomas, M. Dero, A. Cancel. J.M. Ruiz, B. Schatz and J.M. Kuhn, Pharmacokinetics and efficacy of a long-acting formulation of the new somatostatin analog BIM 23014 in patients with acromegaly, J. Clin. Endocrinol. Metab. 76 (1993) 721-727.
6. V.J. Csernus, B. Szende and A.V. Schally, Release of peptides from delivery systems (microcapsules and microparticles) in vivo, Int. J. Pharm. 35 (1990) 557-565.
7. J. Sandow, K. Stoeckemann and G. Jerabek-Sandow, Pharmacokinetics and endocrine effects of slow release formulations of LHRH analogues. J. Steroid Biochem. Mol. Biol. 37 (1990) 925-931.
8. T. Heya, H. Okada, Y. Tanigawara, Y. Ogawa and H. Toguchi. Effect of counteranion of TRH and loading amount on control of TRH release from copoly(dl-lactic/glycolic acid) microspheres prepared by an in-water drying method. Int. J. Pharm. 69 (1991) 69-75.
9. Y. Ogawa, H. Okada, M. Yamamoto and T. Shimamoto. In vivo release profiles of leuprolide acetate from microcapsules prepared with polylactic acids or copolyGactic/ glycolic) acids and in vivo degradation of these polymers. Chem. Pharm. Bull. 36 (1988) 2576-2581.
10. S. Kamei, Y. Inoue, H. Okada, M. Yamada, Y. Ogawa and H. Toguchi, New method for analysis of biodegradable polyesters by high-performance liquid chromatography after alkali hydrolysis, Biomaterials 13 (1992) 953-958.
11. G. Spenlehauer, M. Vert, J.P. Benoit and A. Boddaert, In vitro and in vivo degradation of poly(D,L-lactide/glycolide) type microspheres made by solvent evaporation method, Biomaterials 10 (1989) 557-563.
12. M. Therin, P. Christel, S. Li, H. Garreau and M. Vert, In vivo degradation of massive poly(α-hydroxy acids): Validation of in vitro findings. Biomaterials, 13 (1992) 594-600.
13. S.M. Li, H. Garreau and M. Vert, Structure-property relation-ships in the case of the degradation of massive aliphatic poly (α-hydroxy acids) in aqueous media. Part 1: Poly(DL-lactic acid), J. Mater. Sci. Mater. Med. 1 (1990) 123-130.
14. S.M. Li, H. Garreau and M. Vert, Structure-property relationships in the case of the degradation of massive poly(α-hydroxy acids) in aqueous media. Part 2: Degradation of lactide-glycolide copolymers: PLA37.5GA25 and PLA75GA25, J. Mater. Sci. Mater. Med. 1 (1990) 131-139.
15. S.M. Li, H. Carreau and M. Vert, Structure-property relationships in the case of the degradation of massive poly(α-hy-droxy acids) in aqueous media. Part 3: Influence of the morphology of poly(L-lactic acid), J. Mater. Sci. Mater. Med. 1 (1990) 198-206.
16. M. Vert, S. Li and H. Garreau, More about the degradation of LA/GA-derived matrices in aqueous media, J. Control. Rel. 16 (1991) 15-26.
17. S. Kamei, Y. Iinuma, Y. Yuasa, A. Saikawa, Y. Igari and Y. Ogawa, LHRH agonist depot formulations: Comparative studies of Decapeptyl with Enantone, Eur. Hosp. Pharm. 1 (1995) 113-120.