Partial C-terminal unfolding is required for channel formation by staphylococcal α-toxin

Journal of Biological Chemistry

Volumn 271, Issue 15, 1996, Pages 8655-8660

  Vécsey Semjén, Beatrix ^a,b   Möllby, Roland ^b   Van Der Goot, F Gisou ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CIRCULAR DICHROISM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STAPHYLOCOCCUS AUREUS;

BACTERIAL TOXINS; CHLORIDES; CIRCULAR DICHROISM; EXOTOXINS; HEMOLYSIN PROTEINS; HYDROGEN-ION CONCENTRATION; ION CHANNELS; PROTEIN STRUCTURE, SECONDARY; SPECTROPHOTOMETRY, ULTRAVIOLET; TRYPTOPHAN;

STAPHYLOCOCCUS AUREUS;

EID: 0029991990     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.15.8655     Document Type: Article

References (45)

1. Thelestam, M., and Blomqvist, L. (1988) Toxicon 26, 51-65
2. Bhakdi, S , and Tranum-Jensen, J. (1991) Microbiol. Rev. 55, 733-751
3. McCartney, C., and Arbuthnott, J. (1978) in Bacterial Toxins and Cell Membranes (Wadström, T., and Jeljaszewicz, J., eds) pp. 89-127, Academic Press Inc., London
4. Hildebrand, A., Pohl, M., and Bhakdi, S. (1991) J. Biol. Chem. 266, 17195-17200
5. Tobkes, N., Wallace, B. A., and Bayley, H. (1985) Biochemistry 24, 1915-1920
6. Gouaux, J. E , Braha, O., Hobaugh, M. H., Song, L., Cheley, S., Shustak, C., and Bayley, H. (1994) Proc. Natl. Acad Sci. U S. A. 91, 12828-12831
7. Ikigai, H., and Nakae, T. (1985) Biochem. Biophys. Res. Commun. 130, 175-181
8. Menestrina, G , Belmonte, G., Parisi, V., and Morante, S. (1992) FEMS Microbiol Immunol 105, 19-28
9. Blomqvist, L., Bergman, T., Thelestam, M , and Jórnvall, H (1987) Febs Lett. 211, 127-132
10. Walker, B., Krishnasastry, M., Zorn, L., and Bayley, H. (1992) J. Biol. Chem. 267, 21782-21786
11. Palmer, M., Weller, U., Messner, M., and Bhakdi, S. (1993) J. Biol. Chem. 268, 11963-11967
12. Walker, B., Krishnasastry, M., and Bayley, H. (1993) J. Biol. Chem. 268, 5285-5292
13. Valeva, A , Palmer, M., Hilgert, K., Kehoe, M., and Bhakdi, S. (1995) Biochim. Biophys Acta 1236, 213-218
14. Ward, R. J., Palmer, M., Leonard, K , and Bhakdi, S. (1994) Biochemistry 33, 7477-7484
15. Krishnasastry, M., Walker, B., Braha, O , and Bayley, H. (1994) FEBS Lett. 356, 66-71
16. Walker, B., and Bayley, H. (1994) Protein, Eng. 7, 91-97
17. Walker, B., and Bayley, H. (1995) J. Biol. Chem. 270, 23065-23071
18. Panchal, R. G., and Bayley, H. (1995) J. Biol. Chem. 270, 23072-23076
19. Forti, S., and Menestrina, G. (1989) Eur. J Biochem 181, 767-773
20. Harshman, S , Boquet, P., Duflot, E., Alouf, J. E., Montecucco, C., and Papini, E. (1989) J. Biol. Chem 264, 14978-14984
21. Lind, I, Ahnert-Hilger, G, Fuchs, G., and Gratzl, M. (1987) Anal. Biochem. 164, 84-89
22. Szoka, F. J., and Papahadjopoulos, D. (1978) Proc. Natl. Acad Sci. U. S A 75, 4194-4198
23. van der Goot, F. G., Wong, K. R., Pattus, F., and Buckley, J. T. (1993) Biochemistry 32, 2636-2642
24. Winiski, A. P., McLaughlin, A. C., McDaniel, R. V., Eisenberg, M., and McLaughlin, S. (1986) Biochemistry 25, 8206-8214
25. van der Goot, F. G., Gonzalez-Mañas, J. M., Lakey, J. H., and Pattus, F. (1991) Nature 354, 408-410
26. van der Goot, F. G , Hardie, K. R., Parker, M. W , and Buckley, J. T. (1994) J. Biol. Chem. 269, 30496-30501
27. Ikigai, H , and Nakae, T. (1987) J Biol. Chem. 262, 2156-2160
28. Tomita, T., Watanabe, M., and Yasuda, T. (1992) J. Biol. Chem 267, 13391-13397
29. Arnold, K., Hoekstra, D., and Ohki, S. (1992) Biochim. Biaphys. Acta 1124, 88-94
30. Menestrina, G. (1986) J. Membr. Biol. 90, 177-190
31. Thelestam, M., Olofsson, A., Blomqvist, L., and Hebert, H. (1991) Biochim. Biophys. Acta 1062, 245-254
32. Vaz, W. L C., Nicksch, A., and Jähnig, F (1978) Eur. J Biochem. 83, 299-305
33. Winiski, A. P., Eisenberg, M., Langner, M , and McLaughlin, S (1988) Biochemistry 27, 386-392
34. Freskgard, P.-O., Martensson, L.-G., Jonasson, P., Jonsson, B.-H., and Carlsson, U. (1994) Biochemistry 33, 14281-14288
35. Manavalan, P , and Johnson, W. C (1983) Nature 305, 831-832
36. Manning, M. C., and Woody, R. (1989) Biochemistry 28, 8609-8613
37. van der Goot, F., Ausio, J., Wong, K., Pattus, F., and Buckley, J. (1993) J. Biol. Chem. 268, 18272-18279
38. van der Goot, F. G., Lakey, J. H., and Pattus, F. (1992) Trends Cell Biol. 2, 343-348
39. London, E. (1992) Mol. Microbiol 6, 3277-3282
40. Parker, M. W., and Pattus, F. (1993) Trends Biochem. Sci. 18, 391-395
41. van der Goot, F. G., Parker, M., Pattus, F., and Buckley, J. T. (1994) Toxicology 87, 1-28
42. Milne, J C., Furlong, D., Hanna, P. C., Wall, J. S., and Collier, R. J. (1994) J. Biol. Chem 269, 20607-20612
43. Ballard, J., Sokolov, Y., Yuan, W.-L , Kagan, B. L., and Tweten, R. K. (1993) Mol. Microbiol. 10, 627-634
44. Boulnois, G. J., Paton, J. C., Mitchell, T. J , and Andrew, P. W. (1991) Mol. Microbiol 5, 2611-2616
45. Koehler, T. M., and Collier, R. J. (1991) Mol Microbiol 5, 1501-1506