메뉴 건너뛰기




Volumn 11, Issue 4, 1996, Pages 396-407

Current concepts of hepatic uptake, intracellular transport and biliary secretion of bile acids: Physiological basis and pathophysiological changes in cholestatic liver dysfunction

Author keywords

bile secretion; bile transport; cholestatic liver dysfunction; hepatic uptake; pathophysiological changes; physiological aspects

Indexed keywords

BILE ACID; CARRIER PROTEIN; CHLORPROMAZINE; ETHINYLESTRADIOL; TAUROLITHOCHOLIC ACID;

EID: 0029991949     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.1996.tb01390.x     Document Type: Review
Times cited : (16)

References (154)
  • 1
    • 0003742258 scopus 로고
    • Physiology of bile secretion and enterohepatic circulation, in: Physiology of the Gastrointestinal Tract
    • 1 Erlinger S. Physiology of bile secretion and enterohepatic circulation. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. New York: Raven Press, 1987 ; 1557–80.
    • (1987) , pp. 1557-80
    • Erlinger, S.1
  • 2
    • 0026562055 scopus 로고
    • Hepatic transport systems regulating pH, cell volume, and bile secretion
    • 2 Boyer JL, Graf J., Meier PJ. Hepatic transport systems regulating pH, cell volume, and bile secretion. Annu. Rev. Physiol. 1992 ; 54: 415–38.
    • (1992) Annu. Rev. Physiol. , vol.54 , pp. 415-38
    • Boyer, JL1    Graf, J.2    Meier, PJ.3
  • 3
    • 0024550129 scopus 로고
    • Overview of epithelial polarity
    • 3 Handler JS. Overview of epithelial polarity. Annu. Rev. Physiol. 1989 ; 51: 729–40.
    • (1989) Annu. Rev. Physiol. , vol.51 , pp. 729-40
    • Handler, JS.1
  • 4
    • 0023091381 scopus 로고
    • The effect of changes in the fluid state of rat liver plasma membrane in the transport of taurocholate
    • 4 Mills PR, Meier PJ, Smith DJ, Ballatori N., Boyer JL, Gordon ER. The effect of changes in the fluid state of rat liver plasma membrane in the transport of taurocholate. Hepatology 1987 ; 7: 61–6.
    • (1987) Hepatology , vol.7 , pp. 61-6
    • Mills, PR1    Meier, PJ2    Smith, DJ3    Ballatori, N.4    Boyer, JL5    Gordon, ER.6
  • 5
    • 0023882264 scopus 로고
    • The transport of bile acids in liver cells
    • 5 Frimmer M., Ziegler K. The transport of bile acids in liver cells. Biochim. Biophys. Acta 1988 ; 947: 75–99.
    • (1988) Biochim. Biophys. Acta , vol.947 , pp. 75-99
    • Frimmer, M.1    Ziegler, K.2
  • 6
    • 0020966926 scopus 로고
    • Characterization of the bile acid transport system in normal and transformed hepatocytes
    • 6 Von Dippe P., Levy D. Characterization of the bile acid transport system in normal and transformed hepatocytes. J. Biol. Chemistry 1983 ; 258: 8896–901.
    • (1983) J. Biol. Chemistry , vol.258 , pp. 8896-901
    • Von Dippe, P.1    Levy, D.2
  • 7
    • 0026048728 scopus 로고
    • Isolation and characterization of canalicular and basolateral plasma membrane fractions from human liver
    • 7 Wolters H., Spiering M., Gerding A. et al. Isolation and characterization of canalicular and basolateral plasma membrane fractions from human liver. Biochim. Biophys. Acta 1991 ; 1069: 61–69.
    • (1991) Biochim. Biophys. Acta , vol.1069 , pp. 61-69
    • Wolters, H.1    Spiering, M.2    Gerding, A.3
  • 8
    • 0027081369 scopus 로고
    • Adenosine triphosphate‐dependent taurocholate transport in human liver plasma membranes
    • 8 Wolters H., Kuipers F., Sloof MJH, Vonk RJ. Adenosine triphosphate‐dependent taurocholate transport in human liver plasma membranes. J. Clin. Invest. 1992 ; 90: 2321–6.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2321-6
    • Wolters, H.1    Kuipers, F.2    Sloof, MJH3    Vonk, RJ.4
  • 9
    • 0020464777 scopus 로고
    • Taurocholate transport by rat liver sinusoidal membrane vesicles: Evidence of sodium cotransport
    • 9 Inoue M., Kinne R., Trans T., Arias IM. Taurocholate transport by rat liver sinusoidal membrane vesicles: Evidence of sodium cotransport. Hepatology 1982 ; 2: 572–9.
    • (1982) Hepatology , vol.2 , pp. 572-9
    • Inoue, M.1    Kinne, R.2    Trans, T.3    Arias, IM.4
  • 10
    • 0021349075 scopus 로고
    • Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver
    • 10 Meier PJ, Sztul ES, Reuben A., Boyer JL. Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver. J. Cell Biol. 1984 ; 98: 991–1000.
    • (1984) J. Cell Biol. , vol.98 , pp. 991-1000
    • Meier, PJ1    Sztul, ES2    Reuben, A.3    Boyer, JL.4
  • 11
    • 0022981885 scopus 로고
    • Purification and reconstitution of the bile acid transport system from hepatocyte sinusoidal plasma membranes
    • 11 Von Dippe P., Anathanarayanan M., Drain P., Levy D. Purification and reconstitution of the bile acid transport system from hepatocyte sinusoidal plasma membranes. Biochim. Biophys. Acta 1986 ; 862: 352–60.
    • (1986) Biochim. Biophys. Acta , vol.862 , pp. 352-60
    • Von Dippe, P.1    Anathanarayanan, M.2    Drain, P.3    Levy, D.4
  • 12
    • 0021347303 scopus 로고
    • Further characterization of membrane proteins involved in the transport of organic anions in hepatocytes. Comparison of two different affinity labels: 4,4′‐Diisothiocyano‐1,2‐diphenylethane‐2,2′‐disulfonic acid and brominated taurodehydro‐cholic acid
    • 12 Ziegler K., Frimmer M., Fasold H. Further characterization of membrane proteins involved in the transport of organic anions in hepatocytes. Comparison of two different affinity labels: 4,4′‐Diisothiocyano‐1,2‐diphenylethane‐2,2′‐disulfonic acid and brominated taurodehydro‐cholic acid. Biochem. Biophys. Acta 1984 ; 769: 117–29.
    • (1984) Biochem. Biophys. Acta , vol.769 , pp. 117-29
    • Ziegler, K.1    Frimmer, M.2    Fasold, H.3
  • 13
    • 0021258518 scopus 로고
    • 3′‐Isothiocyanatobenzamido [3H]‐cholate: A new affinity label for hepatocellular membrane proteins responsible for the uptake of both bile acids and pholloidin
    • 13 Ziegler K., Frimmer M., Mullner S., Fasold H. 3′‐Isothiocyanatobenzamido [ 3 H]‐cholate: A new affinity label for hepatocellular membrane proteins responsible for the uptake of both bile acids and pholloidin. Biochim. Biophys. Acta 1984 ; 773: 11–22.
    • (1984) Biochim. Biophys. Acta , vol.773 , pp. 11-22
    • Ziegler, K.1    Frimmer, M.2    Mullner, S.3    Fasold, H.4
  • 14
    • 0021219288 scopus 로고
    • Identity of hepatic membrane transports systems for bile salts, phalloidin and antamahide by photoaffinity labelling
    • 14 Wieland T., Nassal M., Kramer W., Fricker G., Bickel U., Kurz G. Identity of hepatic membrane transports systems for bile salts, phalloidin and antamahide by photoaffinity labelling. Proc. Natl Acad. Sci. USA 1984 ; 81: 5232–6.
    • (1984) Proc. Natl Acad. Sci. USA , vol.81 , pp. 5232-6
    • Wieland, T.1    Nassal, M.2    Kramer, W.3    Fricker, G.4    Bickel, U.5    Kurz, G.6
  • 15
    • 0020420242 scopus 로고
    • Bile salt‐binding polypeptides in plasma membranes of hepatocytes revealed by photoaffanity labelling
    • 15 Kramer W., Bickel U., Buscher H‐P, Gerok W., Kurz G. Bile salt‐binding polypeptides in plasma membranes of hepatocytes revealed by photoaffanity labelling. Eur. J. Biochem. 1982 ; 129: 13–24.
    • (1982) Eur. J. Biochem. , vol.129 , pp. 13-24
    • Kramer, W.1    Bickel, U.2    Buscher, H‐P3    Gerok, W.4    Kurz, G.5
  • 16
    • 0024252246 scopus 로고
    • Transport systems for amphipathic compounds in normal and neoplastic hepatocytes
    • 16 Buscher HP, Gerok W., Kollinger M. et al. Transport systems for amphipathic compounds in normal and neoplastic hepatocytes. Adv. Enzyme Reg. 1988 ; 27: 173–92.
    • (1988) Adv. Enzyme Reg. , vol.27 , pp. 173-92
    • Buscher, HP1    Gerok, W.2    Kollinger, M.3
  • 17
    • 0023280162 scopus 로고
    • Biochemistry of bile secretion
    • 17 Coleman R. Biochemistry of bile secretion. Biochem. J. 1987 ; 244: 249–61.
    • (1987) Biochem. J. , vol.244 , pp. 249-61
    • Coleman, R.1
  • 18
    • 0019320931 scopus 로고
    • Characterization of the anion transport system in hepatocyte plasma membranes
    • 18 Cheng S., Levy D. Characterization of the anion transport system in hepatocyte plasma membranes. J. Biol. Chem. 1980 ; 255: 2637–40.
    • (1980) J. Biol. Chem. , vol.255 , pp. 2637-40
    • Cheng, S.1    Levy, D.2
  • 19
    • 0021929498 scopus 로고
    • Further characterization of 3′‐isothiocyanatobenzamido [3H]‐cholate binding to hepatocytes. Correlation with bile acid transport inhibition and protection by substrates and inhibitors
    • 19 Ziegler K. Further characterization of 3′‐isothiocyanatobenzamido [ 3 H]‐cholate binding to hepatocytes. Correlation with bile acid transport inhibition and protection by substrates and inhibitors. Biochim. Biophys. Acta 1985 ; 819: 37–44.
    • (1985) Biochim. Biophys. Acta , vol.819 , pp. 37-44
    • Ziegler, K.1
  • 20
    • 85120516899 scopus 로고
    • Characterization of the cloned rat liver sodium‐bile acid cotransporter using c‐terminal and fusin protein antibodies
    • 20 Ananthanarayanan M., Ng OC, Boyer JL, Suchy FJ. Characterization of the cloned rat liver sodium‐bile acid cotransporter using c‐terminal and fusin protein antibodies. Hepatology 1993 ; 18: 320A.
    • (1993) Hepatology , vol.18 , pp. 320A
    • Ananthanarayanan, M.1    Ng, OC2    Boyer, JL3    Suchy, FJ.4
  • 21
    • 84882776731 scopus 로고
    • Molecular properties of the Na+‐dependent taurocholate cotransporting polypeptide (Ntcp) of rat liver
    • 21 Stieger B., Hagenbuch B., Cornacchia L., Schroeder A., Landmann L., Meier PJ. Molecular properties of the Na + ‐dependent taurocholate cotransporting polypeptide (Ntcp) of rat liver. Hepatology 1993 ; 18: 345A.
    • (1993) Hepatology , vol.18 , pp. 345A
    • Stieger, B.1    Hagenbuch, B.2    Cornacchia, L.3    Schroeder, A.4    Landmann, L.5    Meier, PJ.6
  • 22
    • 0023449851 scopus 로고
    • cDNA cloning for a bile canaliculus domain‐specific membrane glycoprotein of rat hepatocytes
    • 22 Hong W., Doyle D. cDNA cloning for a bile canaliculus domain‐specific membrane glycoprotein of rat hepatocytes. Proc. Natl Acad. Sci. USA 1987 ; 84: 7962–6.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 7962-6
    • Hong, W.1    Doyle, D.2
  • 23
    • 0023735806 scopus 로고
    • Functional reconstitution of the canalicular bile‐salt transport system of rat liver
    • 23 Ruetz S., Hugetobler G., Meier PJ. Functional reconstitution of the canalicular bile‐salt transport system of rat liver. Proc. Natl Acad. Sci. USA. 1988 ; 85: 6147–51.
    • (1988) Proc. Natl Acad. Sci. USA. , vol.85 , pp. 6147-51
    • Ruetz, S.1    Hugetobler, G.2    Meier, PJ.3
  • 24
    • 0025349737 scopus 로고
    • Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: An analysis by tissue distribution, purification and N‐terminal amino acid sequence
    • 24 McCaughan GW, Wickson JE, Creswick PF, Gorrell MD. Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: An analysis by tissue distribution, purification and N‐terminal amino acid sequence. Heptology 1990 ; 11: 534–44.
    • (1990) Heptology , vol.11 , pp. 534-44
    • McCaughan, GW1    Wickson, JE2    Creswick, PF3    Gorrell, MD.4
  • 25
    • 0023726623 scopus 로고
    • Direct evidence for the binding of rat liver DPP IV to collagen in vitro
    • 25 Hanski C., Huhle T., Gossrau R., Reutter W. Direct evidence for the binding of rat liver DPP IV to collagen in vitro. Exp. Cell Res. 1988 ; 178: 64–72.
    • (1988) Exp. Cell Res. , vol.178 , pp. 64-72
    • Hanski, C.1    Huhle, T.2    Gossrau, R.3    Reutter, W.4
  • 26
    • 0026554451 scopus 로고
    • Derminants in the hepatic uptake of organic anions
    • 26 Tiribelli C. Derminants in the hepatic uptake of organic anions. J. Hepatol. 1992 ; 14: 385–90.
    • (1992) J. Hepatol. , vol.14 , pp. 385-90
    • Tiribelli, C.1
  • 27
    • 0025333328 scopus 로고
    • Isolation and characterization of the canalicular membrane bile acid transport protein of rat liver
    • 27 Sippel CJ, Ananthanarayanan M., Suchy F. Isolation and characterization of the canalicular membrane bile acid transport protein of rat liver. Am. J. Physiol. 1990 ; 258: G728–37.
    • (1990) Am. J. Physiol. , vol.258 , pp. G728-37
    • Sippel, CJ1    Ananthanarayanan, M.2    Suchy, F.3
  • 28
    • 0022349247 scopus 로고
    • Monoclonal antibodies to the glucose transporter from human erythrocytes. Identification of the transporter as a MW 55 000 protein
    • 28 Allard WJ, Lienhard GE. Monoclonal antibodies to the glucose transporter from human erythrocytes. Identification of the transporter as a MW 55 000 protein. J. Biol. Chem. 1985 ; 260: 8668–75.
    • (1985) J. Biol. Chem. , vol.260 , pp. 8668-75
    • Allard, WJ1    Lienhard, GE.2
  • 29
    • 85120516694 scopus 로고
    • Monoclonal antibodies that bind the renal Na+/glucose symport system. 1. Identification
    • 29 Wu JR, Lever JE. Monoclonal antibodies that bind the renal Na + /glucose symport system. 1. Identification. Biochim. Biophys. Ada 1989 ; 985: 133–8.
    • (1989) Biochim. Biophys. Ada , vol.985 , pp. 133-8
    • Wu, JR1    Lever, JE.2
  • 30
    • 0025250354 scopus 로고
    • Expression of the bile acid transport protein during liver development and in hepatoma cells
    • 30 Von Dippe P., Levy D. Expression of the bile acid transport protein during liver development and in hepatoma cells. J. Biol. Chem. 1990 ; 265: 5942–5.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5942-5
    • Von Dippe, P.1    Levy, D.2
  • 31
    • 0024972420 scopus 로고
    • Identification of an M 75 000 component of the H+/D‐glucose cotransporter from Zea mays with monoclonal antibodies directed against the mammalian Na+/D‐glucose cotransporter
    • 31 Rausch T., Raszeja‐Specht A., Koepsell H. Identification of an M 75 000 component of the H + /D‐glucose cotransporter from Zea mays with monoclonal antibodies directed against the mammalian Na + /D‐glucose cotransporter. Biochim. Biophys. Acta 1989 ; 985: 1333–8.
    • (1989) Biochim. Biophys. Acta , vol.985 , pp. 1333-8
    • Rausch, T.1    Raszeja‐Specht, A.2    Koepsell, H.3
  • 32
    • 0023916831 scopus 로고
    • Identification of the hepatocyte Na+‐dependent bile acid transport protein using monoclonal antibodies
    • 32 Ananthanarayanan M., Von Dippe P., Levy D. Identification of the hepatocyte Na + ‐dependent bile acid transport protein using monoclonal antibodies. J. Biol. Chem. 1988 ; 263: 8338–43.
    • (1988) J. Biol. Chem. , vol.263 , pp. 8338-43
    • Ananthanarayanan, M.1    Von Dippe, P.2    Levy, D.3
  • 33
    • 0019224595 scopus 로고
    • New concepts of mechanisms of hepatocyte bile formation
    • 33 Boyer JL. New concepts of mechanisms of hepatocyte bile formation. Physiol. Rev. 1980 ; 60: 303–26.
    • (1980) Physiol. Rev. , vol.60 , pp. 303-26
    • Boyer, JL.1
  • 34
    • 85120510940 scopus 로고
    • Scanning electron microscopy of the liver, in: Progress in Liver Diseases
    • 34 Motta PM. Scanning electron microscopy of the liver. In: Popper H., Schaffner F., eds., Progress in Liver Diseases. New York: Grune and Stratton, 1982 ; 1–16.
    • (1982) , pp. 1-16
    • Motta, PM.1
  • 35
    • 0019829944 scopus 로고
    • Transport of sodium, chloride and taurocholate by cultured rat hepatocytes
    • 35 Scharschmidt BF, Stephens JE. Transport of sodium, chloride and taurocholate by cultured rat hepatocytes. Proc. Natl Acad. Sci. USA 1981 ; 78: 986–90.
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , pp. 986-90
    • Scharschmidt, BF1    Stephens, JE.2
  • 36
    • 0017092068 scopus 로고
    • Uptake of bile acids by perfused rat liver
    • 36 Reichen J., Paumgartner G. Uptake of bile acids by perfused rat liver. Am. J. Physiol. 1976 ; 231: 735–40.
    • (1976) Am. J. Physiol. , vol.231 , pp. 735-40
    • Reichen, J.1    Paumgartner, G.2
  • 37
    • 0018237326 scopus 로고
    • Effect of Na+ mobile acid uptake by isolated rat hepatocytes. Evidence for a hetergonous system
    • 37 Anwer MS, Hegner D. Effect of Na + mobile acid uptake by isolated rat hepatocytes. Evidence for a hetergonous system. Hoppe-Seyler's Z. Physiol. Chem. 1978 ; 359: 181–92.
    • (1978) Hoppe-Seyler's Z. Physiol. Chem. , vol.359 , pp. 181-92
    • Anwer, MS1    Hegner, D.2
  • 38
    • 0022446332 scopus 로고
    • Effects of ethinyl estradiol on substrate uptake and efflux by isolated rat hepatocytes
    • 38 Stacey NH. Effects of ethinyl estradiol on substrate uptake and efflux by isolated rat hepatocytes. Biochem. Pharmacol. 1986 ; 35: 2495–500.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 2495-500
    • Stacey, NH.1
  • 39
    • 0023727843 scopus 로고
    • Effects of chlorpromazine on taurocholate transport in isolated rat hepatocytes
    • 39 Stacey NH. Effects of chlorpromazine on taurocholate transport in isolated rat hepatocytes. Biochem. Pharmacol. 1988 ; 37: 4129–34.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 4129-34
    • Stacey, NH.1
  • 40
    • 0023811891 scopus 로고
    • Inhibition of taurocholate transport by cyclosporin A in cultured rat hepatocytes
    • 40 Kukongviriyapan V., Stacey NH. Inhibition of taurocholate transport by cyclosporin A in cultured rat hepatocytes. J. Pharmacol. Exp. Ther. 1988 ; 247: 685–9.
    • (1988) J. Pharmacol. Exp. Ther. , vol.247 , pp. 685-9
    • Kukongviriyapan, V.1    Stacey, NH.2
  • 41
    • 0024359410 scopus 로고
    • Multispecificity of Na+‐dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane
    • 41 Zimmerli B., Valantinas J., Meier PJ. Multispecificity of Na + ‐dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane. J. Pharmacol. Exp. Ther. 1989 ; 250: 301–8.
    • (1989) J. Pharmacol. Exp. Ther. , vol.250 , pp. 301-8
    • Zimmerli, B.1    Valantinas, J.2    Meier, PJ.3
  • 42
    • 0021704435 scopus 로고
    • Driving forces in hepatocellular uptake of phalloidin and cholate
    • 42 Petzinger E., Frimmer M. Driving forces in hepatocellular uptake of phalloidin and cholate. Biochim. Biophys. Acta 1984 ; 778: 539–48.
    • (1984) Biochim. Biophys. Acta , vol.778 , pp. 539-48
    • Petzinger, E.1    Frimmer, M.2
  • 43
    • 0023642472 scopus 로고
    • Sodium‐dependent taurocholate uptake by isolated rat hepatocytes occurs through an electrogenic mechanism
    • 43 Bear CE, Davidson JS, Shaff EA. Sodium‐dependent taurocholate uptake by isolated rat hepatocytes occurs through an electrogenic mechanism. Biochim. Biophys. Acta 1987 ; 903: 388–94.
    • (1987) Biochim. Biophys. Acta , vol.903 , pp. 388-94
    • Bear, CE1    Davidson, JS2    Shaff, EA.3
  • 44
    • 84908825680 scopus 로고
    • Cloning and expression of a cDNA encoding the chloride‐dependent sulfobromophthalein (BSP) uptake system of rat liver
    • 44 Jacquemin E., Hagenkuch B., Steiger B., Wolkoff AW. Cloning and expression of a cDNA encoding the chloride‐dependent sulfobromophthalein (BSP) uptake system of rat liver. Hepatology 1992 ; 16: 89A.
    • (1992) Hepatology , vol.16 , pp. 89A
    • Jacquemin, E.1    Hagenkuch, B.2    Steiger, B.3    Wolkoff, AW.4
  • 45
    • 0004625655 scopus 로고
    • Mechanisms of bile secretion and hepatic transport, in: Physiology of Membrane Disorders
    • 45 Boyer JL. Mechanisms of bile secretion and hepatic transport: In: Andreoli TE, Hoffman JF, Fanestil DD, Schultz SG, eds., Physiology of Membrane Disorders. New York: Plenum Publishing, 1986 ; 609–36.
    • (1986) , pp. 609-36
    • Boyer, JL.1
  • 46
    • 0020617090 scopus 로고
    • Direct determination of the driving forces of taurocholate uptake into rat liver, plasma membrane vesicles
    • 46 Duffy MC, Blitzer BL, Boyer JL. Direct determination of the driving forces of taurocholate uptake into rat liver, plasma membrane vesicles. J. Clin. Invest. 1983 ; 72: 1470–81.
    • (1983) J. Clin. Invest. , vol.72 , pp. 1470-81
    • Duffy, MC1    Blitzer, BL2    Boyer, JL.3
  • 47
    • 0040276377 scopus 로고
    • Occurrence of a multispecific transporter for the hepatocellular accumulation of bile acids and various cyclopeptides, in: Bile Acids and the Liver
    • 47 Petzinger E., Ziegler K., Frimmer M. Occurrence of a multispecific transporter for the hepatocellular accumulation of bile acids and various cyclopeptides. In: Paumgartner G., Stiehl A., Gerok W., eds., Bile Acids and the Liver. Boston: MTP Press, 1987 ; 111–24.
    • (1987) , pp. 111-24
    • Petzinger, E.1    Ziegler, K.2    Frimmer, M.3
  • 48
    • 0026021332 scopus 로고
    • Specificity of the hepatocyte Na+‐dependent taurocholate transporter: Influence of side chain length and charge
    • 48 Hardison WG, Heasley VL, Shellhamer DF. Specificity of the hepatocyte Na + ‐dependent taurocholate transporter: Influence of side chain length and charge. Hepatology 1991 ; 13: 68–72.
    • (1991) Hepatology , vol.13 , pp. 68-72
    • Hardison, WG1    Heasley, VL2    Shellhamer, DF.3
  • 49
    • 0022136024 scopus 로고
    • Effect of glucagon on hepatic taurocholate uptake: Relationship to membrane potential
    • 49 Edmondson JW, Miller BA, Lumeng L. Effect of glucagon on hepatic taurocholate uptake: Relationship to membrane potential. Am. J. Physiol. 1985 ; 249: G427–33.
    • (1985) Am. J. Physiol. , vol.249 , pp. G427-33
    • Edmondson, JW1    Miller, BA2    Lumeng, L.3
  • 50
    • 0347071124 scopus 로고
    • Hepatocellular uptake of oleate is energy dependent, sodium linked, and inhibited by an antibody to a hepatocyte plasma membrane fatty acid binding protein
    • 50 Stremmel W., Strohmeyer G., Berk PD. Hepatocellular uptake of oleate is energy dependent, sodium linked, and inhibited by an antibody to a hepatocyte plasma membrane fatty acid binding protein. Proc. Natl Acad. Sci. USA 1986 ; 83: 3584–8.
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 3584-8
    • Stremmel, W.1    Strohmeyer, G.2    Berk, PD.3
  • 51
    • 0023106660 scopus 로고
    • Stremmel W. Role of plasma membrane ligand‐binding protein in the hepatocellular uptake of albumin‐bound organic anions
    • 51 Berk PD, Potter BJ. Stremmel W. Role of plasma membrane ligand‐binding protein in the hepatocellular uptake of albumin‐bound organic anions. Hepatology 1987 ; 7: 165–76.
    • (1987) Hepatology , vol.7 , pp. 165-76
    • Berk, PD1    Potter, BJ.2
  • 52
    • 0023034942 scopus 로고
    • Hydroxyl/bile acid exchange. A new mechanism for the uphill transport of cholate by basolateral plasma membrane vesicles
    • 52 Blitzer BL, Terzakis C., Scott KA. Hydroxyl/bile acid exchange. A new mechanism for the uphill transport of cholate by basolateral plasma membrane vesicles. J. Biol. Chem. 1986 ; 261: 12042–6.
    • (1986) J. Biol. Chem. , vol.261 , pp. 12042-6
    • Blitzer, BL1    Terzakis, C.2    Scott, KA.3
  • 53
    • 9844240987 scopus 로고
    • Identification of a single sinusoidal bile salt uptake system in skate liver
    • 53 Fricker G., Hugenber G., Meier PJ, Kurz G., Boyer JL. Identification of a single sinusoidal bile salt uptake system in skate liver. Am. J. Physiol. 1987 ; 253: G816–22.
    • (1987) Am. J. Physiol. , vol.253 , pp. G816-22
    • Fricker, G.1    Hugenber, G.2    Meier, PJ3    Kurz, G.4    Boyer, JL.5
  • 54
    • 0023258295 scopus 로고
    • Bile acid inhibition of taurocholate uptake by rat hepatocytes: Role of OH groups
    • 54 Bellentani S., Hardison WGM, Marchengiano P., Zanasi G., Manenti F. Bile acid inhibition of taurocholate uptake by rat hepatocytes: Role of OH groups. Am. J. Physiol. 1987 ; 252: G339–44.
    • (1987) Am. J. Physiol. , vol.252 , pp. G339-44
    • Bellentani, S.1    Hardison, WGM2    Marchengiano, P.3    Zanasi, G.4    Manenti, F.5
  • 55
    • 0021855165 scopus 로고
    • Modified somatostations as inhibitors of a multispecific transport system for bile acids and phallotoxins in isolated hepatocytes
    • 55 Ziegler K., Frimmer M., Kesser H. et al. Modified somatostations as inhibitors of a multispecific transport system for bile acids and phallotoxins in isolated hepatocytes. Biochim. Biophys. Acta 1985 ; 845: 86–93.
    • (1985) Biochim. Biophys. Acta , vol.845 , pp. 86-93
    • Ziegler, K.1    Frimmer, M.2    Kesser, H.3
  • 56
    • 85120516592 scopus 로고
    • Transport processes at the canalicular surface of rat hepatocytes, in: Modulation of Liver Cell Expression
    • 56 Meier PJ. Transport processes at the canalicular surface of rat hepatocytes. In: Reutter W., Popper H., Arias IM, Heinrich PC, Keppler D., Landmann L., eds. Modulation of Liver Cell Expression. Boston: MTP Press, 1986 ; 127–41.
    • (1986) , pp. 127-41
    • Meier, PJ.1
  • 57
    • 0025250504 scopus 로고
    • Role of intracellular organelles in the hepatic transport of bile acids
    • 57 Erlinger S. Role of intracellular organelles in the hepatic transport of bile acids. Biomed. Pharmacother. 1990 ; 44: 409–16.
    • (1990) Biomed. Pharmacother. , vol.44 , pp. 409-16
    • Erlinger, S.1
  • 58
    • 0020571418 scopus 로고
    • Newly identified bile acid binders in rat liver cytosol. Purification and comparison with glutathione S‐transferase
    • 58 Sugiyama Y., Yamada T., Kapolwitz N. Newly identified bile acid binders in rat liver cytosol. Purification and comparison with glutathione S‐transferase. J. Biol. Chem. 1983 ; 258: 3602–7.
    • (1983) J. Biol. Chem. , vol.258 , pp. 3602-7
    • Sugiyama, Y.1    Yamada, T.2    Kapolwitz, N.3
  • 59
    • 0021689219 scopus 로고
    • Identification and purification of a 36 kDa bile acid binder in human hepatic cytosol
    • 59 Stolz A., Sugiyama Y., Kuhlenkemp J., Kaplowitz N. Identification and purification of a 36 kDa bile acid binder in human hepatic cytosol. FEBS Lett. 1984 ; 177: 31–5.
    • (1984) FEBS Lett. , vol.177 , pp. 31-5
    • Stolz, A.1    Sugiyama, Y.2    Kuhlenkemp, J.3    Kaplowitz, N.4
  • 60
    • 0022531009 scopus 로고
    • Cytosolic bile acid binding proteins in rat liver: Radioimmunoassay, molecular forms developmental characteristics and organ distribution
    • 60 Stolz A., Sugiyama Y., Kuhlenkemp J. et al. Cytosolic bile acid binding proteins in rat liver: Radioimmunoassay, molecular forms developmental characteristics and organ distribution. Hepatology 1986 ; 6: 433–9.
    • (1986) Hepatology , vol.6 , pp. 433-9
    • Stolz, A.1    Sugiyama, Y.2    Kuhlenkemp, J.3
  • 61
    • 0022479074 scopus 로고
    • Comparison of the affinities of newly identified human bile acid binder and cationic glutathione S‐transferase for bile acid
    • 61 Takikawa H., Stolz A., Sugimoto M., Sugiyama Y., Kaplowitz N. Comparison of the affinities of newly identified human bile acid binder and cationic glutathione S‐transferase for bile acid. J. Lipid Res. 1986 ; 27: 652–7.
    • (1986) J. Lipid Res. , vol.27 , pp. 652-7
    • Takikawa, H.1    Stolz, A.2    Sugimoto, M.3    Sugiyama, Y.4    Kaplowitz, N.5
  • 63
    • 0023922017 scopus 로고
    • Comparison of the effects of bile acids and GSH on the fluorescence of bound 1‐anilino‐8‐naphthalene sulfonate and the enzymatic activity of cationic and neutral human hepatic GSH S‐transferases
    • 63 Takikawa H., Sugiyama Y., Kaplowitz N. Comparison of the effects of bile acids and GSH on the fluorescence of bound 1‐anilino‐8‐naphthalene sulfonate and the enzymatic activity of cationic and neutral human hepatic GSH S‐transferases. Biochim. Biophys. Acta 1988 ; 954: 37–43.
    • (1988) Biochim. Biophys. Acta , vol.954 , pp. 37-43
    • Takikawa, H.1    Sugiyama, Y.2    Kaplowitz, N.3
  • 64
    • 0023138036 scopus 로고
    • 3α‐hydroxysteroid dehydrogenase activity of the Y bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significance
    • 64 Stolz A., Takikawa H., Sugiyama Y., Kuhlenkamp J., Kaplowitz N. 3α‐hydroxysteroid dehydrogenase activity of the Y bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significance. J. Clin. Invest. 1987 ; 79: 427–34.
    • (1987) J. Clin. Invest. , vol.79 , pp. 427-34
    • Stolz, A.1    Takikawa, H.2    Sugiyama, Y.3    Kuhlenkamp, J.4    Kaplowitz, N.5
  • 66
    • 0025071722 scopus 로고
    • Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver
    • 66 Takikawa H., Stolz A., Sugiyama Y., Yoshida H., Yamanaka M., Kaplowitz N. Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver. J. Biol. Chem. 1990 ; 265: 2132–6.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2132-6
    • Takikawa, H.1    Stolz, A.2    Sugiyama, Y.3    Yoshida, H.4    Yamanaka, M.5    Kaplowitz, N.6
  • 67
    • 0022998098 scopus 로고
    • Binding of bile acids, oleic acid, and organic anions by rat and human hepatic Z protein
    • 67 Takikawa H., Kaplowitz N. Binding of bile acids, oleic acid, and organic anions by rat and human hepatic Z protein. Arch. Biochem. Biophys. 1986 ; 251: 385–92.
    • (1986) Arch. Biochem. Biophys. , vol.251 , pp. 385-92
    • Takikawa, H.1    Kaplowitz, N.2
  • 68
    • 0024519221 scopus 로고
    • The role of cytoplasmic proteins in hepatic bile acid transport
    • 68 Stolz A., Takikawa H., Ookhtens M., Kaplowitz N. The role of cytoplasmic proteins in hepatic bile acid transport. Annu. Rev. Physiol. 1989 ; 51: 161–76.
    • (1989) Annu. Rev. Physiol. , vol.51 , pp. 161-76
    • Stolz, A.1    Takikawa, H.2    Ookhtens, M.3    Kaplowitz, N.4
  • 69
    • 84955519043 scopus 로고
    • Intracellular bile acid transport in rat liver as visualized by electron microscopy autoradiography using a bile acid analogue
    • 69 Suchy FJ, Balistreri WF, Hung J., Miller P., Garfield SA. Intracellular bile acid transport in rat liver as visualized by electron microscopy autoradiography using a bile acid analogue. Am J. Physiol. 1983 ; 2465: G681–9.
    • (1983) Am J. Physiol. , vol.2465 , pp. G681-9
    • Suchy, FJ1    Balistreri, WF2    Hung, J.3    Miller, P.4    Garfield, SA.5
  • 70
    • 0020754069 scopus 로고
    • Hepatic handling of bile salts and protein during intrahepatic cholestasis
    • 70 Goldsmith MA, Huling S., Jones AL. Hepatic handling of bile salts and protein during intrahepatic cholestasis. Gastroenterology 1983 ; 84: 978–86.
    • (1983) Gastroenterology , vol.84 , pp. 978-86
    • Goldsmith, MA1    Huling, S.2    Jones, AL.3
  • 71
    • 0020373511 scopus 로고
    • Changes of the Golgi apparatus induced by diethylmaleate in rat hepatocytes
    • 71 Jezequel AM, Bonazzi P., Amabili P., Venturini C., Orlandi F. Changes of the Golgi apparatus induced by diethylmaleate in rat hepatocytes. Hepatology 1982 ; 2: 856–62.
    • (1982) Hepatology , vol.2 , pp. 856-62
    • Jezequel, AM1    Bonazzi, P.2    Amabili, P.3    Venturini, C.4    Orlandi, F.5
  • 72
    • 0023806390 scopus 로고
    • Immunoperoxidase localization of bile salts in rat liver cells: Evidence for a role of the Golgi apparatus in bile salt transport
    • 72 Lamri Y., Roda A., Dumont M., Feldmann G., Erlinger S. Immunoperoxidase localization of bile salts in rat liver cells: Evidence for a role of the Golgi apparatus in bile salt transport. J. Clin. Invest. 1988 ; 82: 1173–82.
    • (1988) J. Clin. Invest. , vol.82 , pp. 1173-82
    • Lamri, Y.1    Roda, A.2    Dumont, M.3    Feldmann, G.4    Erlinger, S.5
  • 73
    • 0023954159 scopus 로고
    • Role of the hepatocyte microtubular system in the excretion of bile salts and biliary lipid: Implications for intracellular vesicular transport
    • 73 Crawford JM, Berken CA, Gollan JL. Role of the hepatocyte microtubular system in the excretion of bile salts and biliary lipid: Implications for intracellular vesicular transport. J. Lipid Res. 1988 ; 29: 144–56.
    • (1988) J. Lipid Res. , vol.29 , pp. 144-56
    • Crawford, JM1    Berken, CA2    Gollan, JL.3
  • 74
    • 0022453515 scopus 로고
    • Biology of disease. Mechanisms of cholestasis
    • 74 Phillips MJ, Poucell S., Oda M. Biology of disease. Mechanisms of cholestasis. Lab. Invest. 1986 ; 54: 593–608.
    • (1986) Lab. Invest. , vol.54 , pp. 593-608
    • Phillips, MJ1    Poucell, S.2    Oda, M.3
  • 75
    • 0027685887 scopus 로고
    • Microtubule‐dependent transport of bile salts through hepatocytes: Cholic vs taurocholic acid
    • 75 Crawford JM, Crawford AR, Strahs DCJ. Microtubule‐dependent transport of bile salts through hepatocytes: Cholic vs taurocholic acid. Hepatology 1993 ; 18: 903–11.
    • (1993) Hepatology , vol.18 , pp. 903-11
    • Crawford, JM1    Crawford, AR2    Strahs, DCJ.3
  • 76
    • 0002343964 scopus 로고
    • The enterohepatic circulation, in: The Liver: Biology and Pathobiology
    • 76 Carey MC, Cahalane MJ. The enterohepatic circulation. In: Arias I., Jakoby WB, Popper H., Schacter D., Shafritz DA, eds. The Liver: Biology and Pathobiology. New York: Raven Press, 1988 ; 573–616.
    • (1988) , pp. 573-616
    • Carey, MC1    Cahalane, MJ.2
  • 77
    • 0000431508 scopus 로고
    • Metabolism of bile acids in intestinal microflora, in: Sterols and Bile Acids
    • 77 Hylemon PB. Metabolism of bile acids in intestinal microflora. In: Danielsson H., Sjovall J., eds., Sterols and Bile Acids, Vol. 12, Amsterdam: Elsevier, 1985 ; 331–43.
    • (1985) , vol.12 , pp. 331-43
    • Hylemon, PB.1
  • 78
    • 0021920983 scopus 로고
    • Ontogeny of hepatic bile acid conjugation in the rat
    • 78 Suchy FJ, Courchene SM, Balistreri WF. Ontogeny of hepatic bile acid conjugation in the rat. Pediatr. Res. 1985 ; 19: 97–101.
    • (1985) Pediatr. Res. , vol.19 , pp. 97-101
    • Suchy, FJ1    Courchene, SM2    Balistreri, WF.3
  • 79
    • 0023654462 scopus 로고
    • Bile acid: CoASH ligases from guinea‐pig and porcine liver microsomes: Purification and characterization
    • 79 Vessey DA, Benfatto AM, Kempner ES. Bile acid: CoASH ligases from guinea‐pig and porcine liver microsomes: Purification and characterization. J. Biol. Chem. 1987 ; 262: 5360–5.
    • (1987) J. Biol. Chem. , vol.262 , pp. 5360-5
    • Vessey, DA1    Benfatto, AM2    Kempner, ES.3
  • 80
    • 0025866940 scopus 로고
    • Purification and characterization of bile acid‐CoA amino acid N‐acyltransferase from human liver
    • 80 Johnson MR, Barnes S., Kwakye JB, Diasio RB. Purification and characterization of bile acid‐CoA amino acid N‐acyltransferase from human liver. J. Biol. Chem. 1991 ; 266: 10277–33.
    • (1991) J. Biol. Chem. , vol.266 , pp. 10277-33
    • Johnson, MR1    Barnes, S.2    Kwakye, JB3    Diasio, RB.4
  • 81
    • 0027320860 scopus 로고
    • Effects of dibutyryl cyclic AMP and papaverine on intrahepatocytic bile acid transport. Role of vesicle transport
    • 81 Hoshino M., Ohiwa T., Hayakawa T. et al. Effects of dibutyryl cyclic AMP and papaverine on intrahepatocytic bile acid transport. Role of vesicle transport. Scand. J. Gastroenterol. 1993 ; 28: 833–8.
    • (1993) Scand. J. Gastroenterol. , vol.28 , pp. 833-8
    • Hoshino, M.1    Ohiwa, T.2    Hayakawa, T.3
  • 82
    • 0023137161 scopus 로고
    • Properties of the canalicular bile acid transport system in rat liver
    • 82 Meier PJ, Meier‐Abt. A., Boyer JL. Properties of the canalicular bile acid transport system in rat liver. Biochem. J. 1987 ; 242: 465–9.
    • (1987) Biochem. J. , vol.242 , pp. 465-9
    • Meier, PJ1    Meier‐Abt, A.2    Boyer, JL.3
  • 83
    • 0021250574 scopus 로고
    • Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles
    • 83 Meier PJ, Meier‐Abt. A., Barrett C., Boyer JL. Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. J. Biol. Chem. 1984 ; 259: 10614–22.
    • (1984) J. Biol. Chem. , vol.259 , pp. 10614-22
    • Meier, PJ1    Meier‐Abt, A.2    Barrett, C.3    Boyer, JL.4
  • 84
    • 0022133449 scopus 로고
    • Influence of side‐chain charge on hepatic transport of bile acid and bile acid analogues
    • 84 Anwer MS, O'Maille ERL, Hofmann AF, Dipietro RA, Michelotti E. Influence of side‐chain charge on hepatic transport of bile acid and bile acid analogues. Am. J. Physiol. 1985 ; 249: G479–88.
    • (1985) Am. J. Physiol. , vol.249 , pp. G479-88
    • Anwer, MS1    O'Maille, ERL2    Hofmann, AF3    Dipietro, RA4    Michelotti, E.5
  • 85
    • 0026044685 scopus 로고
    • ATP‐dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110‐kDa glycoprotein binding ATP and bile salt
    • 85 Muller M., Ishikawa R., Berger U. et al. ATP‐dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110‐kDa glycoprotein binding ATP and bile salt. J. Biol. Chem. 1991 ; 226: 18920–6.
    • (1991) J. Biol. Chem. , vol.226 , pp. 18920-6
    • Muller, M.1    Ishikawa, R.2    Berger, U.3
  • 86
    • 0026077224 scopus 로고
    • ATP‐dependent taurocholate transport by rat‐liver canalicular membrane vesicles
    • 86 Adachi Y., Kobayashi H., Kurumi Y., Shouji M., Kitano M., Yamamoto T. ATP‐dependent taurocholate transport by rat‐liver canalicular membrane vesicles. Hepatology 1991 ; 14: 655–9.
    • (1991) Hepatology , vol.14 , pp. 655-9
    • Adachi, Y.1    Kobayashi, H.2    Kurumi, Y.3    Shouji, M.4    Kitano, M.5    Yamamoto, T.6
  • 87
    • 0025991571 scopus 로고
    • Rat liver canalicular membrane vesicles contain an ATP‐dependent bile acid transport system
    • 87 Nishida T., Gatmaitan Z., Che M., Arias IM. Rat liver canalicular membrane vesicles contain an ATP‐dependent bile acid transport system. Proc. Natl Acad. Sci. USA 1991 ; 88: 6590–4.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 6590-4
    • Nishida, T.1    Gatmaitan, Z.2    Che, M.3    Arias, IM.4
  • 88
    • 0026529394 scopus 로고
    • ATP‐dependent bile‐salt transport in canalicular rat liver plasma‐membrane vesicles
    • 88 Stieger B., O'Neill B., Meier PJ. ATP‐dependent bile‐salt transport in canalicular rat liver plasma‐membrane vesicles. Biochem. J. 1992 ; 284: 67–74.
    • (1992) Biochem. J. , vol.284 , pp. 67-74
    • Stieger, B.1    O'Neill, B.2    Meier, PJ.3
  • 89
    • 0020604269 scopus 로고
    • Rat liver canalicular membrane vesicles: Isolation and topological characterization
    • 89 Inoue M., Kienne R., Tran T., Biempica L., Arias IM. Rat liver canalicular membrane vesicles: Isolation and topological characterization. J. Biol. Chem. 1983 ; 258: 5183–8.
    • (1983) J. Biol. Chem. , vol.258 , pp. 5183-8
    • Inoue, M.1    Kienne, R.2    Tran, T.3    Biempica, L.4    Arias, IM.5
  • 90
    • 0020352520 scopus 로고
    • Effect of chlorpromazine on hepatic clearance and excretion of bile acids by the isolated perfused rat liver
    • 90 Tavolini N., Reed JS, Boyer JL. Effect of chlorpromazine on hepatic clearance and excretion of bile acids by the isolated perfused rat liver. Proc. Soc. Exp. Biol. Med. 1982 ; 170: 486–92.
    • (1982) Proc. Soc. Exp. Biol. Med. , vol.170 , pp. 486-92
    • Tavolini, N.1    Reed, JS2    Boyer, JL.3
  • 91
    • 0026707595 scopus 로고
    • Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes
    • 91 Okudaira K., Yamazaki M., Sawada Y., Sugiyama Y., Iga T., Hanano M. Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes. Pharm. Res. 1992 ; 9: 1152–6.
    • (1992) Pharm. Res. , vol.9 , pp. 1152-6
    • Okudaira, K.1    Yamazaki, M.2    Sawada, Y.3    Sugiyama, Y.4    Iga, T.5    Hanano, M.6
  • 92
    • 0026091090 scopus 로고
    • Effects of cyclosporin A in vivo on taurocholate uptake by rat hepatocytes
    • 92 Azer SA, Stacey NH. Effects of cyclosporin A in vivo on taurocholate uptake by rat hepatocytes. Biochem. Pharmacol. 1991 ; 42: 2053–7.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 2053-7
    • Azer, SA1    Stacey, NH.2
  • 93
    • 0023766272 scopus 로고
    • Inhibition of taurocholate and ouabain in isolated rat hepatocytes by cyclosporin A
    • 93 Stacey NH, Kotecka B. Inhibition of taurocholate and ouabain in isolated rat hepatocytes by cyclosporin A. Gastroenterology 1988 ; 95: 780–6.
    • (1988) Gastroenterology , vol.95 , pp. 780-6
    • Stacey, NH1    Kotecka, B.2
  • 94
    • 0027258109 scopus 로고
    • Differential effects of cyclosporin A on the transport of bile acids by human hepatocytes
    • 94 Azer SA, Stacey NH. Differential effects of cyclosporin A on the transport of bile acids by human hepatocytes. Biochem. Pharmacol. 1993 ; 46: 813–19.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 813-19
    • Azer, SA1    Stacey, NH.2
  • 95
    • 0025362577 scopus 로고
    • Inhibition of bile acid transport by cyclosporin A in rat liver plasma membrane vesicles
    • 95 Moseley RH, Johnson TR, Morrissette JM. Inhibition of bile acid transport by cyclosporin A in rat liver plasma membrane vesicles. J. Pharmacol. Exp. Ther. 1990 ; 253: 974–80.
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 974-80
    • Moseley, RH1    Johnson, TR2    Morrissette, JM.3
  • 96
    • 0019500767 scopus 로고
    • Protoporphyrininduced cholestasis in the isolated in situ perfused rat liver
    • 96 Avner DL, Lee RG, Berenson MM. Protoporphyrininduced cholestasis in the isolated in situ perfused rat liver. J. Clin. Invest. 1981 ; 67: 385–94.
    • (1981) J. Clin. Invest. , vol.67 , pp. 385-94
    • Avner, DL1    Lee, RG2    Berenson, MM.3
  • 97
    • 0020064726 scopus 로고
    • Uptake of cholic acid by freshly isolated rat hepatocytes: Presence of a common carrier for bile acid transports
    • 97 Ohkuma S., Kuriyama K. Uptake of cholic acid by freshly isolated rat hepatocytes: Presence of a common carrier for bile acid transports. Steroids 1982 ; 39: 7–19.
    • (1982) Steroids , vol.39 , pp. 7-19
    • Ohkuma, S.1    Kuriyama, K.2
  • 98
    • 0025840323 scopus 로고
    • Mechanism of inhibition of hepatic bile acid uptake by amiloride and 4,4′‐diisothiocyano‐2,2′‐disulfonicstilbene (DIDS)
    • 98 Anwer MS, Branson AU, Atkinson JM. Mechanism of inhibition of hepatic bile acid uptake by amiloride and 4,4′‐diisothiocyano‐2,2′‐disulfonicstilbene (DIDS). Biochem. Pharmacol. 1991 ; 42: S135–41.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. S135-41
    • Anwer, MS1    Branson, AU2    Atkinson, JM.3
  • 99
    • 0025190695 scopus 로고
    • Interference with hepatocellular substrate uptake by 1,1,1,‐trichloroethane and tetrachloroethylene
    • 99 Kukongviriyapan V., Kukongviriyapan U., Stacey NH. Interference with hepatocellular substrate uptake by 1,1,1,‐trichloroethane and tetrachloroethylene. Toxicol. Appl. Pharmacol. 1990 ; 102, 80–90.
    • (1990) Toxicol. Appl. Pharmacol. , vol.102 , pp. 80-90
    • Kukongviriyapan, V.1    Kukongviriyapan, U.2    Stacey, NH.3
  • 100
    • 0017658152 scopus 로고
    • Cholestatic steroid hormones inhibit taurocholate uptake into isolated rat hepatocytes
    • 100 Schwarz LR, Schenk M., Pfaff E., Greim H. Cholestatic steroid hormones inhibit taurocholate uptake into isolated rat hepatocytes. Biochem. Pharmacol. 1977 ; 26: 2433–7.
    • (1977) Biochem. Pharmacol. , vol.26 , pp. 2433-7
    • Schwarz, LR1    Schenk, M.2    Pfaff, E.3    Greim, H.4
  • 101
    • 0027294025 scopus 로고
    • Mechanism of trichloroethylene‐induced elevation of individual serum bile acids. II. In vitro and in vivo interference by trichloroethylene with bile acid transport in isolated rat hepatocytes
    • 101 Bai CL, Stacey NH. Mechanism of trichloroethylene‐induced elevation of individual serum bile acids. II. In vitro and in vivo interference by trichloroethylene with bile acid transport in isolated rat hepatocytes. Toxicol. Appl. Pharmacol 1993 ; 121: 296–302.
    • (1993) Toxicol. Appl. Pharmacol , vol.121 , pp. 296-302
    • Bai, CL1    Stacey, NH.2
  • 102
    • 0019430327 scopus 로고
    • The role of microfilaments and microtubules in taurocholate uptake by isolated rat liver cells
    • 102 Reichen J., Berman MD, Berk PD. The role of microfilaments and microtubules in taurocholate uptake by isolated rat liver cells. Biochim. Biophys. Acta 1981 ; 643: 126–33.
    • (1981) Biochim. Biophys. Acta , vol.643 , pp. 126-33
    • Reichen, J.1    Berman, MD2    Berk, PD.3
  • 104
    • 0023890366 scopus 로고
    • Hepatocellular cytoskeleton reorganization after phalloidin intoxication. An immunomorphological view
    • 104 Biagini G., Ballardini G., Fallani M. et al. Hepatocellular cytoskeleton reorganization after phalloidin intoxication. An immunomorphological view. Cell. Mol. Biol. 1988 ; 34: 165–74.
    • (1988) Cell. Mol. Biol. , vol.34 , pp. 165-74
    • Biagini, G.1    Ballardini, G.2    Fallani, M.3
  • 105
    • 0021353170 scopus 로고
    • Cholestasis induced by estradiol‐17β‐D‐glucuronide: Mechanisms and prevention by sodium taurocholate
    • 105 Adinolfi LE, Utili R., Gaeta GB, Abernathy CO, Zimmerman HJ. Cholestasis induced by estradiol‐17β‐D‐glucuronide: Mechanisms and prevention by sodium taurocholate. Hepatology 1984 ; 4: 30–7.
    • (1984) Hepatology , vol.4 , pp. 30-7
    • Adinolfi, LE1    Utili, R.2    Gaeta, GB3    Abernathy, CO4    Zimmerman, HJ.5
  • 106
    • 0023259578 scopus 로고
    • Increase in biliary permeability subsequent to intrahepatic cholestasis by estradiol valerate in rats
    • 106 Jaeschke H., Trummer E., Krell H. Increase in biliary permeability subsequent to intrahepatic cholestasis by estradiol valerate in rats. Gastroenterology 1987 ; 93: 533–8.
    • (1987) Gastroenterology , vol.93 , pp. 533-8
    • Jaeschke, H.1    Trummer, E.2    Krell, H.3
  • 107
    • 0024397618 scopus 로고
    • Chlorpromazine administrated in vivo and in vitro inhibits the efflux of bile acids in freshly isolated rat hepatocytes
    • 107 Willson RA, Hart JR, Hall T. Chlorpromazine administrated in vivo and in vitro inhibits the efflux of bile acids in freshly isolated rat hepatocytes. Pharmacol. Toxicol. 1989 ; 64: 454–8.
    • (1989) Pharmacol. Toxicol. , vol.64 , pp. 454-8
    • Willson, RA1    Hart, JR2    Hall, T.3
  • 108
    • 77952031701 scopus 로고
    • Two separate transport systems for nonbile acid organic anions: Studies in normal and TR‐rat canalicular membrane vesicles
    • 108 Nishida T., Gatmaitan Z., Che M., Arias IM. Two separate transport systems for nonbile acid organic anions: Studies in normal and TR‐rat canalicular membrane vesicles. Hepatology 1991 ; 14: 92A.
    • (1991) Hepatology , vol.14 , pp. 92A
    • Nishida, T.1    Gatmaitan, Z.2    Che, M.3    Arias, IM.4
  • 109
    • 0026516095 scopus 로고
    • ATP‐dependent organic anion transport system in normal and TR‐rat liver canalicular membranes
    • 109 Nishida T., Hardenbrook C., Gatmaitan Z., Arias IM. ATP‐dependent organic anion transport system in normal and TR‐rat liver canalicular membranes. Am. J. Physiol. 1992 ; 262: G629–35.
    • (1992) Am. J. Physiol. , vol.262 , pp. G629-35
    • Nishida, T.1    Hardenbrook, C.2    Gatmaitan, Z.3    Arias, IM.4
  • 110
    • 0023940614 scopus 로고
    • Ethinylestradiol administration selectively alters liver sinusoidal membrane lipid fluidity and protein composition
    • 110 Rosario J., Sutherland E., Zaccaro L., Simon FR. Ethinylestradiol administration selectively alters liver sinusoidal membrane lipid fluidity and protein composition. Biochemistry 1988 ; 27: 3939–46.
    • (1988) Biochemistry , vol.27 , pp. 3939-46
    • Rosario, J.1    Sutherland, E.2    Zaccaro, L.3    Simon, FR.4
  • 111
    • 0018973009 scopus 로고
    • Alteration of rat liver plasma membrane fluidity and ATPase activity by chlorpromazine hydrochloride and its metabolites
    • 111 Keeffe EB, Blankenship NM, Scharschmidt BF. Alteration of rat liver plasma membrane fluidity and ATPase activity by chlorpromazine hydrochloride and its metabolites. Gastroenterology 1980 ; 79: 222–31.
    • (1980) Gastroenterology , vol.79 , pp. 222-31
    • Keeffe, EB1    Blankenship, NM2    Scharschmidt, BF.3
  • 112
    • 0027372874 scopus 로고
    • Organic solvents increase membrane fluidity and affect bile flow and K+ transport in rat liver
    • 112 Thalhammer T., Kaschnitz R., Mittermayer K., Haddad P., Graf J. Organic solvents increase membrane fluidity and affect bile flow and K + transport in rat liver. Biochem. Pharmacol. 1993 ; 46: 1207–15.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1207-15
    • Thalhammer, T.1    Kaschnitz, R.2    Mittermayer, K.3    Haddad, P.4    Graf, J.5
  • 113
    • 0027333214 scopus 로고
    • Cholestatic potentials of α‐naphthylisothiocyanate (ANIT) and β‐naphthylisothiocyanate in the isolated perfused rat liver
    • 113 Kossor DC, Handler JA, Dulik DM, Meunier PC, Leonard TB, Goldstein RS. Cholestatic potentials of α‐naphthylisothiocyanate (ANIT) and β‐naphthylisothiocyanate in the isolated perfused rat liver. Biochem. Pharmacol. 1993 ; 46: 2061–6.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 2061-6
    • Kossor, DC1    Handler, JA2    Dulik, DM3    Meunier, PC4    Leonard, TB5    Goldstein, RS.6
  • 114
    • 0024351792 scopus 로고
    • Oestradiol 17β‐glucuronide increases tight‐junctional permeability in rat liver
    • 114 Kan KS, Monte MJ, Parslow RA, Coleman R. Oestradiol 17β‐glucuronide increases tight‐junctional permeability in rat liver. Biochem. J. 1989 ; 261: 297–300.
    • (1989) Biochem. J. , vol.261 , pp. 297-300
    • Kan, KS1    Monte, MJ2    Parslow, RA3    Coleman, R.4
  • 115
    • 0014287967 scopus 로고
    • Effects of sodium taurolithocholate on bile flow and bile acid excretion
    • 115 Javitt NB, Emerman S. Effects of sodium taurolithocholate on bile flow and bile acid excretion. J. Clin. Invest. 1968 ; 47: 1002–14.
    • (1968) J. Clin. Invest. , vol.47 , pp. 1002-14
    • Javitt, NB1    Emerman, S.2
  • 116
    • 0023948979 scopus 로고
    • Cholestasis and the interactions of sulfated glyco‐ and taurolithocholate with calcium
    • 116 Van der Meer R., Vonk RJ, Kuipers F. Cholestasis and the interactions of sulfated glyco‐ and taurolithocholate with calcium. Am. J. Physiol. 1988 ; 254: G644–9.
    • (1988) Am. J. Physiol. , vol.254 , pp. G644-9
    • Van der Meer, R.1    Vonk, RJ2    Kuipers, F.3
  • 117
    • 0025369522 scopus 로고
    • Formation of biliary thrombi in protoporphyrininduced cholestasis in perfused rat liver
    • 117 Berenson MM, Gunther C., Samowitz WS, Bjorman DJ. Formation of biliary thrombi in protoporphyrininduced cholestasis in perfused rat liver. Hepatology 1990 ; 11: 757–63.
    • (1990) Hepatology , vol.11 , pp. 757-63
    • Berenson, MM1    Gunther, C.2    Samowitz, WS3    Bjorman, DJ.4
  • 118
    • 0022571349 scopus 로고
    • Modification of biliary tree permeability in rats treated with a manganese‐bilirubin combination
    • 118 Ayotte P., Plaa GL. Modification of biliary tree permeability in rats treated with a manganese‐bilirubin combination. Toxicol. Appl. Pharmacol. 1986 ; 84: 295–303.
    • (1986) Toxicol. Appl. Pharmacol. , vol.84 , pp. 295-303
    • Ayotte, P.1    Plaa, GL.2
  • 119
    • 0027340407 scopus 로고
    • Temporal relationship of changes in hepatobiliary function and morphology in rats following α‐naphthylisothiocyanate (ANIT) administration
    • 119 Kossor DC, Meunier PC, Handler JA, Sozio RS, Goldstein RS. Temporal relationship of changes in hepatobiliary function and morphology in rats following α‐naphthylisothiocyanate (ANIT) administration. Toxicol. Appl. Pharmacol. 1993 ; 119: 108–14.
    • (1993) Toxicol. Appl. Pharmacol. , vol.119 , pp. 108-14
    • Kossor, DC1    Meunier, PC2    Handler, JA3    Sozio, RS4    Goldstein, RS.5
  • 120
    • 0017736306 scopus 로고
    • Relationship between bile flow and Na, K‐adenosine triphosphate in liver plasma membranes enriched in bile canaliculi
    • 120 Reichen J., Paumgartner G. Relationship between bile flow and Na, K‐adenosine triphosphate in liver plasma membranes enriched in bile canaliculi. J. Clin. Invest. 1977 ; 60: 429–34.
    • (1977) J. Clin. Invest. , vol.60 , pp. 429-34
    • Reichen, J.1    Paumgartner, G.2
  • 121
    • 0018710515 scopus 로고
    • Inhibition of hepatic Na, K‐adenosine triphosphtase in taurolithocholate induced cholestasis in the rat
    • 121 Reichen J., Paumgartner G. Inhibition of hepatic Na, K‐adenosine triphosphtase in taurolithocholate induced cholestasis in the rat. Experientia 1979 ; 35: 1186–8.
    • (1979) Experientia , vol.35 , pp. 1186-8
    • Reichen, J.1    Paumgartner, G.2
  • 122
    • 0018152061 scopus 로고
    • Effects of chlorpromazine hydrochloride and its metabolites on Mg‐ and Na, K‐ATPase activities of canalicular enriched rat liver plasma membranes
    • 122 Samuels AM, Carey MC. Effects of chlorpromazine hydrochloride and its metabolites on Mg‐ and Na, K‐ATPase activities of canalicular enriched rat liver plasma membranes. Gastroenterology 1978 ; 74: 1183–90.
    • (1978) Gastroenterology , vol.74 , pp. 1183-90
    • Samuels, AM1    Carey, MC.2
  • 123
    • 0021503299 scopus 로고
    • Ethynylestradiol impairs bile salt uptake and Na‐K pump function of rat hepatocytes
    • 123 Berr F., Simon FR, Reichen J. Ethynylestradiol impairs bile salt uptake and Na‐K pump function of rat hepatocytes. Am. J. Physiol. 1984 ; 247: G437–43.
    • (1984) Am. J. Physiol. , vol.247 , pp. G437-43
    • Berr, F.1    Simon, FR2    Reichen, J.3
  • 124
    • 84915665541 scopus 로고
    • Effect of a cholestatic agent on isolated rat hepatocyte function. Toxicol. Appl
    • 124 Lavigne J., Priestly BG, Plaa GL. Effect of a cholestatic agent on isolated rat hepatocyte function. Toxicol. Appl. Pharmacol. 1978 ; 45: 263A.
    • (1978) Pharmacol. , vol.45 , pp. 263A
    • Lavigne, J.1    Priestly, BG2    Plaa, GL.3
  • 125
    • 0028204407 scopus 로고
    • Differential effects of cyclosporin A on transport of bile acids by rat hepatocytes: Relationship to individual serum bile acid levels
    • 125 Azer SA, Stacey NH. Differential effects of cyclosporin A on transport of bile acids by rat hepatocytes: Relationship to individual serum bile acid levels. Toxicol. Appl. Pharmacol. 1994 ; 124: 302–9.
    • (1994) Toxicol. Appl. Pharmacol. , vol.124 , pp. 302-9
    • Azer, SA1    Stacey, NH.2
  • 126
    • 0023773286 scopus 로고
    • Photoaffinity labeling of membrane proteins from rat liver and pig kidney with cyclosporine diazirine
    • 126 Ziegler K., Frimmer M., Koepsell Photoaffinity labeling of membrane proteins from rat liver and pig kidney with cyclosporine diazirine. Transplantation 1988 ; 46: S15–20.
    • (1988) Transplantation , vol.46 , pp. S15-20
    • Ziegler, K.1    Frimmer, M.2    Koepsell3
  • 127
    • 0021251386 scopus 로고
    • Specificity of an Na+‐dependent taurocholate transport site in isolated rat hepatocytes
    • 127 Hardison WGM, Bellentani S., Heasley V., Shellhamer D. Specificity of an Na + ‐dependent taurocholate transport site in isolated rat hepatocytes. Am. J. Physiol. 1984 ; 246: G477–83.
    • (1984) Am. J. Physiol. , vol.246 , pp. G477-83
    • Hardison, WGM1    Bellentani, S.2    Heasley, V.3    Shellhamer, D.4
  • 128
    • 0028962949 scopus 로고
    • Mechanisms of ketoconazole‐induced serum bile acid rises in rats: Relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes
    • 128 Azer SA, Kukongviriyapan V., Stacey NH. Mechanisms of ketoconazole‐induced serum bile acid rises in rats: Relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes. J. Pharmacol. Exp. Ther. 1995 ; 272: 1231–7.
    • (1995) J. Pharmacol. Exp. Ther. , vol.272 , pp. 1231-7
    • Azer, SA1    Kukongviriyapan, V.2    Stacey, NH.3
  • 129
    • 0003078576 scopus 로고
    • Cholestasis, in: The Liver: Biology and Pathobiology
    • 129 Reichen J., Simon FR. Cholestasis. In: Arias WB, Jakoby H., Popper H., Schachter D., Shafritz DA, eds. The Liver: Biology and Pathobiology. New York: Raven Press, 1988 ; 1105–24.
    • (1988) , pp. 1105-24
    • Reichen, J.1    Simon, FR.2
  • 130
    • 0018598941 scopus 로고
    • Chlorpromazine and its metabolites alter polymerization and gelatin of actin
    • 130 Elias E., Boyer JL. Chlorpromazine and its metabolites alter polymerization and gelatin of actin. Science 1979 ; 206: 1404–6.
    • (1979) Science , vol.206 , pp. 1404-6
    • Elias, E.1    Boyer, JL.2
  • 131
    • 0024412436 scopus 로고
    • Hepatic immunohistochemical localization of tight junction protein ZO‐1 in rat models of cholestasis
    • 131 Anderson JM, Glade JL, Stevenson BR, Boxer JL, Mooseker MS. Hepatic immunohistochemical localization of tight junction protein ZO‐1 in rat models of cholestasis. Am. J. Pathol. 1989 ; 134: 1055–62.
    • (1989) Am. J. Pathol. , vol.134 , pp. 1055-62
    • Anderson, JM1    Glade, JL2    Stevenson, BR3    Boxer, JL4    Mooseker, MS.5
  • 132
    • 0001855664 scopus 로고
    • Mechanisms of cholestasis, in: Hepatic Transport of Bile Secretion: Physiology and Pathophysiology
    • 132 Reichen J. Mechanisms of cholestasis. In: Tavoloni N., Berk PD, eds., Hepatic Transport of Bile Secretion: Physiology and Pathophysiology. New York: Raven Press, 1993 ; 665–72.
    • (1993) , pp. 665-72
    • Reichen, J.1
  • 133
    • 0026668255 scopus 로고
    • Ethinylestradiol increases volume and decreases sinusoidal membrane surface in the rat liver: A stereslogical analysis
    • 133 Hornstein B., Stammer L., Bianchi L., Landmann L. Ethinylestradiol increases volume and decreases sinusoidal membrane surface in the rat liver: A stereslogical analysis. Hepatology 1992 ; 16: 217–23.
    • (1992) Hepatology , vol.16 , pp. 217-23
    • Hornstein, B.1    Stammer, L.2    Bianchi, L.3    Landmann, L.4
  • 134
    • 0029063415 scopus 로고
    • Hepatoprotection in ethinyl estradiol treated rats is provided by tauroursodeoxycholic acid but not by ursodeoxycholic acid
    • 134 Azer SA, Canfield PJ, Stacey NH. Hepatoprotection in ethinyl estradiol treated rats is provided by tauroursodeoxycholic acid but not by ursodeoxycholic acid. J. Gastroenterol. Hepatol. 1995 ; 10: 261–9.
    • (1995) J. Gastroenterol. Hepatol. , vol.10 , pp. 261-9
    • Azer, SA1    Canfield, PJ2    Stacey, NH.3
  • 136
    • 0023153771 scopus 로고
    • Benign recurrent cholestasis: A light and electron microscopic study with emphasis on sinusoidal cells
    • 136 Raymond JM, Dubuisson L., Quinton A., Bioulac‐Sage P., Balaband C. Benign recurrent cholestasis: A light and electron microscopic study with emphasis on sinusoidal cells. Ultrastruct. Pathol. 1987 ; 11: 11–17.
    • (1987) Ultrastruct. Pathol. , vol.11 , pp. 11-17
    • Raymond, JM1    Dubuisson, L.2    Quinton, A.3    Bioulac‐Sage, P.4    Balaband, C.5
  • 137
    • 0024452479 scopus 로고
    • Extrahepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocyte
    • 137 Fricker G., Landmann L., Meier PJ. Extrahepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocyte. J. Clin. Invest. 1989 ; 84: 876–85.
    • (1989) J. Clin. Invest. , vol.84 , pp. 876-85
    • Fricker, G.1    Landmann, L.2    Meier, PJ.3
  • 138
    • 0025353627 scopus 로고
    • Bile duct ligation‐induced redistribution of canalicular antigen in rat hepatocyte plasma membranes demonstrated by immunogold quantification
    • 138 Landmann L., Meier PJ, Bianchi L. Bile duct ligation‐induced redistribution of canalicular antigen in rat hepatocyte plasma membranes demonstrated by immunogold quantification. Histochemistry 1990 ; 94: 373–9.
    • (1990) Histochemistry , vol.94 , pp. 373-9
    • Landmann, L.1    Meier, PJ2    Bianchi, L.3
  • 139
    • 0023608934 scopus 로고
    • Biogenesis of rat hepatocyte plasma membrane in vivo: Comparison of the pathway taken by spiral and basolateral proteins using subcellular fractionation
    • 139 Bartles JR, Feracci HM, Stieger B., Hubbard AL. Biogenesis of rat hepatocyte plasma membrane in vivo: Comparison of the pathway taken by spiral and basolateral proteins using subcellular fractionation. J. Cell Biol. 1987 ; 105: 1241–51.
    • (1987) J. Cell Biol. , vol.105 , pp. 1241-51
    • Bartles, JR1    Feracci, HM2    Stieger, B.3    Hubbard, AL.4
  • 140
    • 0021733997 scopus 로고
    • The fate of polymeric and secretory immunoglobulin A after retrograde infusion into the common bile duct in rats
    • 140 Jones AL, Mradek GT, Schmucker DL, Underdown BJ. The fate of polymeric and secretory immunoglobulin A after retrograde infusion into the common bile duct in rats. Hepatology 1984 ; 4: 1173–83.
    • (1984) Hepatology , vol.4 , pp. 1173-83
    • Jones, AL1    Mradek, GT2    Schmucker, DL3    Underdown, BJ.4
  • 141
    • 0014586876 scopus 로고
    • Study on the permeability barriers between Disse's space and the bile canaliculi
    • 141 Matter A., Orci L., Rouiller CA. Study on the permeability barriers between Disse's space and the bile canaliculi. J. Ultrasound. Res. Suppl. 1969 ; 11: 1–71.
    • (1969) J. Ultrasound. Res. Suppl. , vol.11 , pp. 1-71
    • Matter, A.1    Orci, L.2    Rouiller, CA.3
  • 142
    • 0021416447 scopus 로고
    • Induction of rat hepatic and intestinal alkaline phosphatase activity produced by bile from bile duct ligated animals
    • 142 Komoda T., Kumegawa M., Yajima T., Tamura G., Alpers DH. Induction of rat hepatic and intestinal alkaline phosphatase activity produced by bile from bile duct ligated animals. Am. J. Physiol. 1984 ; 246: G393–400.
    • (1984) Am. J. Physiol. , vol.246 , pp. G393-400
    • Komoda, T.1    Kumegawa, M.2    Yajima, T.3    Tamura, G.4    Alpers, DH.5
  • 143
    • 0022004092 scopus 로고
    • Liver plasma membrane: The source of high molecular weight alkaline phosphatase in human serum
    • 143 de Brode ME, Roels F., Nouwen EJ, Claeys L., Wieme R. Liver plasma membrane: The source of high molecular weight alkaline phosphatase in human serum. Hepatology 1985 ; 5: 118–28.
    • (1985) Hepatology , vol.5 , pp. 118-28
    • de Brode, ME1    Roels, F.2    Nouwen, EJ3    Claeys, L.4    Wieme, R.5
  • 144
    • 0025083750 scopus 로고
    • Quantitative changes in acid phosphatase, alkaline phosphatase and 5′‐nucleotidase activity in rat liver after experimentally induced cholestasis
    • 144 Frederiks WM, Van Noorden CJF, Aronson DC et al. Quantitative changes in acid phosphatase, alkaline phosphatase and 5′‐nucleotidase activity in rat liver after experimentally induced cholestasis. Liver 1990 ; 10: 158–66.
    • (1990) Liver , vol.10 , pp. 158-66
    • Frederiks, WM1    Van Noorden, CJF2    Aronson, DC3
  • 145
    • 0026723564 scopus 로고
    • Modulation of the liver in cholestasis
    • 145 Desmet VJ. Modulation of the liver in cholestasis. J. Gastroenterol. Hepatol. 1992 ; 7: 313–23.
    • (1992) J. Gastroenterol. Hepatol. , vol.7 , pp. 313-23
    • Desmet, VJ.1
  • 146
    • 0021329124 scopus 로고
    • Role of portal and splenic vein shunts and impaired hepatic extraction in the elevated serum bile acids in liver cirrhosis
    • 146 Ohkubo H., Okuda K., Iida S., Ohnishi K., Ikawa S., Makino I. Role of portal and splenic vein shunts and impaired hepatic extraction in the elevated serum bile acids in liver cirrhosis. Gastroenterology 1984 ; 86: 514–20.
    • (1984) Gastroenterology , vol.86 , pp. 514-20
    • Ohkubo, H.1    Okuda, K.2    Iida, S.3    Ohnishi, K.4    Ikawa, S.5    Makino, I.6
  • 147
    • 0022383994 scopus 로고
    • Hepatic microcirculation in the perfused cirrhotic rat liver
    • 147 Varin F., Huet PM. Hepatic microcirculation in the perfused cirrhotic rat liver. J. Clin. Invest. 1985 ; 76: 1904–12.
    • (1985) J. Clin. Invest. , vol.76 , pp. 1904-12
    • Varin, F.1    Huet, PM.2
  • 148
    • 0024261721 scopus 로고
    • Determinants of hepatic function in liver cirrhosis in the rat. Multivariate analysis
    • 148 Reichen J., Egger B., Ohara N., Zeltner TB, Zysset T., Zimmermann A. Determinants of hepatic function in liver cirrhosis in the rat. Multivariate analysis. J. Clin. Invest. 1988 ; 82: 2069–76.
    • (1988) J. Clin. Invest. , vol.82 , pp. 2069-76
    • Reichen, J.1    Egger, B.2    Ohara, N.3    Zeltner, TB4    Zysset, T.5    Zimmermann, A.6
  • 149
    • 0027372350 scopus 로고
    • Selectivity and sensitivity of changes in serum bile acids during induction of cirrhosis in rats
    • 149 Azer SA, Murray M., Farrell GC, Stacey NH. Selectivity and sensitivity of changes in serum bile acids during induction of cirrhosis in rats. Hepatology 1993 ; 18: 1224–31.
    • (1993) Hepatology , vol.18 , pp. 1224-31
    • Azer, SA1    Murray, M.2    Farrell, GC3    Stacey, NH.4
  • 150
    • 0025277595 scopus 로고
    • Origin, pattern, and mechanisms of bile duct proliferation following biliary obstruction in the rat
    • 150 Slott PA, Liu MH, Tavoloni N. Origin, pattern, and mechanisms of bile duct proliferation following biliary obstruction in the rat. Gastroenterology 1990 ; 99: 466–77.
    • (1990) Gastroenterology , vol.99 , pp. 466-77
    • Slott, PA1    Liu, MH2    Tavoloni, N.3
  • 151
    • 0023014011 scopus 로고
    • Current problems in diagnosis of biliary disease and cholestasis
    • 151 Desmet VJ. Current problems in diagnosis of biliary disease and cholestasis. Semin. Liver Dis. 1986 ; 6: 233–45.
    • (1986) Semin. Liver Dis. , vol.6 , pp. 233-45
    • Desmet, VJ.1
  • 152
    • 0016723035 scopus 로고
    • Fibrosis in chronic liver diseases
    • 152 Popper H., Kent G. Fibrosis in chronic liver diseases. Clin. Gastroenterol. 1975 ; 4: 315–32.
    • (1975) Clin. Gastroenterol. , vol.4 , pp. 315-32
    • Popper, H.1    Kent, G.2
  • 153
    • 84988105354 scopus 로고
    • Fibrogenesis, in: The Liver: Biology and Pathobiology
    • 153 Rojkind M. Fibrogenesis. In: Arias IM, Schacter M., Popper H., Shafritz DA, eds, The Liver: Biology and Pathobiology, New York: Raven Press, 1982 ; 801–9.
    • (1982) , pp. 801-9
    • Rojkind, M.1
  • 154
    • 0025760494 scopus 로고
    • Cellular sources of matrix proteins in experimentally induced cholestatic rat liver
    • 154 Abdel‐Aziz G., Roscan PY, Clement B. et al. Cellular sources of matrix proteins in experimentally induced cholestatic rat liver. J. Pathol. 1991 ; 164: 167–74.
    • (1991) J. Pathol. , vol.164 , pp. 167-74
    • Abdel‐Aziz, G.1    Roscan, PY2    Clement, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.