Preparation of 2-carboxy-3,4-substituted pyrrole haptens and synthesis of porphobilinogen

Tetrahedron Letters

Volumn 37, Issue 14, 1996, Pages 2325-2326

  Adamczyk, Maciej ^a   Reddy, Rajarathnam E ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PORPHOBILINOGEN; PYRROLE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029991944     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00286-9     Document Type: Article

References (16)

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3. c). Environmental Protection Agency, Scientific Advisory Board, Doc. EAP-SAB-CASAC-90-002, 1990.
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6. For reviews see a). Frydman, R. B.; Frydman, B.; Valasinas, A. "The Porphyrins", Ed. Dolphin, D., Acad. Press, New York, 1978, Vol. VI, P 1-123.
7. b). Akthar, M.; Jordan, P. M. in "Comprehensive Organic Chemistry", Ed. Haslam, E., Pergamon Press: Oxford 1979, Vol.5, P.1121.
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9. b). Silbergeld, E. K. U. S. Patent 5,354,652, 1994.
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11. a). Lash, T. D.; Bellettini, J. R.; Bastian, J. A.; Couch, K. B. Synthesis 1994,170.
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13. All new compounds were fully characterized and the yield referred to the homogeneous materials.
14. Battersby, A. R.; Evans, D. A.; Gibson, K. H.; McDonald, E.; Nixon, L. J. Chem. Soc. Perkin Trans 1 1973, 1546.
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16. Battersby, A. R.; Hunt, E.; McDonald, E.; Paine III, J. B. J. Chem. Soc. Perkin Trans 1 1976, 1008.