Value of clinical symptoms, intrathecal specific antibody production and PCR in CSF in the diagnosis of childhood lyme neuroborreliosis

Klinische Padiatrie

Volumn 208, Issue 3, 1996, Pages 106-109

  Issakainen, Jouni ^a,b   Gnehm, Hanspeter E ^a   Lucchini, Gladys Martinetti ^c   Zbinden, Reinhard ^b  

^a Children's Hospital   (Switzerland)

^b CANTONAL HOSPITAL AARAU   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY;

ADOLESCENT; ARTICLE; BORRELIA BURGDORFERI; CEREBROSPINAL FLUID; CHILD; CHILDHOOD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; LYME DISEASE; MALE; POLYMERASE CHAIN REACTION;

EID: 0029991808     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1046456     Document Type: Article

References (14)

1. American Academy of Pediatrics. Committee on Infectious Diseases: Treatment of Lyme borreliosis. Pediatrics 88 (1991) 176-179
2. Aufricht, D., W. Tenner, C. Kohlhauser: Anamnese, Klinik und Labor der kindlichen "aseptischen Meningitis" bei Lymeborreliose - eine Metaanalyse. Klin. Pädiatr. 202 (1990) 396-398
3. Christen, H.-J., F. Hanefeld, H. Eiffert, R. Thomssen: Epidemiology and clinical manifestations of Lyme borreliosis in childhood. A prospective multicentre study with special regard to neuroborreliosis. Acta Paediatr. 82 (1993) S1-S76
4. Halperin, J., B. Luft, A. Anand, C. Roque, O. Alvarez, D. Volkman, R. Dattwyler: Lyme neuroborreliosis: central nervous system manifestations. Neurology 39 (1989) 753-759
5. Hansen, K., M. Crus, H. Link: Oligoclonal Borrelia burgdorferi-specific IgG antibodies in cerebrospinal fluid in Lyme neuroborreliosis. J. Infect. Dis. 161 (1990) 1194-1202
6. Hansen, K., A.-M. Lebech: Lyme neuroborreliosis: a new sensitive diagnostic assay for intrathecal synthesis of Borrelia burgdorferi-specific immunoglobulin G, A and M. Ann. Neurol. 30 (1991) 197-205
7. Horneff, G., H.-I. Huppertz, K. Müller, T. Voit, H. Karch: Demonstration of Borrelia burgdorferi infection in a child with Guillain-Barré syndrome. Eur. J. Pediatr. 152 (1993) 810-812
8. Huppertz, H.-I., H. Schmidt, H. Karch: Detection of Borrelia burgdorferi by nested polymerase chain reaction in cerebrospinal fluid and urine of children with neuroborreliosis. Eur. J. Pediatr. 152 (1993) 414-417
9. Karlsson, M., K. Hovind-Hougen, B. Svenungsson, G. Stiernstedt: Cultivation and characterization of spirochetes from cerebrospinal fluid of patients with Lyme borreliosis. J. Clin. Microbiol. 28 (1990) 473-479
10. Logigian, E., R. Kaplan, A. Steere: Chronic neurologic manifestations of Lyme disease. N. Engl. J. Med. 323 (1990) 1438-1444
11. Nadal, D., R. Gundelfinger, U. Flüeler, E. Boltshauser: Acrodermatitits chronica atrophicans. Arch. Dis. Child. 63 (1988) 72-74
12. Péter, O., A.-G. Bretz, R. Zenhäusern, H. Roten, E. Roulet: Isolement de Borrelia burgdorferi du liquide céphalorachidien de trois enfants avec une atteinte neurologique. Schweiz. Med. Wschr. 123 (1993) 14-19
13. Zbinden, R., J. Stech, W. Bürgi, Th. Meier: Nachweis der intrathekalen Antikörperbildung gegen Borrelia burgdorferi bei Lyme-Neuroborreliose. Schweiz. Med. Wschr. 123 (1993) 2293-2298
14. Zbinden, R., D. Goldenberger, G. Martinetti Lucchini, M. Altwegg: Comparison of two methods for detecting intrathecal synthesis of Borrelia burgdorferi specific antibodies and PCR for diagnosis of Lyme neuroborreliosis. J. Clin. Microbiol. 32 (1994) 1795-1798