Detection of minimal residual disease in childhood acute lymphoblastic leukemia after termination of therapy

Pediatric Hematology and Oncology

Volumn 13, Issue 3, 1996, Pages 257-263

  Wu, Nan Hai ^a   Lu, Shan Gen ^b   Zhu, Ping ^c   Peng, Yu Yun ^a  

^a Yanjing Hospital   (China)

^b Great Wall Hospital   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

acute lymphoblastic leukemia; minimal residual disease; polymerase chain reaction; restriction map

Indexed keywords

ANTINEOPLASTIC AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; FEMALE; GENE REARRANGEMENT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MINIMAL RESIDUAL DISEASE; PATIENT MONITORING; POLYMERASE CHAIN REACTION; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0029991418     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.3109/08880019609030825     Document Type: Article

References (10)

1. Taylor JJ, Rowe D, Williamson IK, Christmas SE, Proctor SJ, Middleton PG. Detection of T-cell receptor γ chain V gene rearrangements using the polymerase chain reaction: Application to the study of clonal disease cells in acute lymphoblastic leukemia. Blood. 1991;77:1989.
2. Brisco MJ, Condon J, Sykes PJ, Neoh SH, Morley AA. Detection and quantitation of neoplastic cells in acute lymphoblastic leukemia, by use of the polymerase chain reaction. Br J Haematol. 1991;79:211.
3. H gene rearrangement events can modify the immunoglobulin heavy chain during progression of B lineage acute lymphoblastic leukemia. Blood. 1992;79:223.
4. Saiki RF, Gelfand DH, Stoffel S, et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science. 1988;239:487.
5. Brisco MJ, Tan LW, Orsborn AM, Morley AA. Development of a highly sensitive assay, based on the polymerase chain reaction, for rare B-lymphocyte clones in a polyclonal population. Br J Haematol. 1990;75:163.
6. Brisco MJ, Condon J, Hughes E, et al. Prognostic significance of detection of monoclonality in remission marrow in acute lymphoblastic leukemia in childhood. Leukemia. 1993;7:1514.
7. γ gene locus. EMBO J. 1987;6:1949.
8. Potter MN, Steward CC, Oakhill A. The significance of detection of minimal residual disease in childhood acute lymphoblastic leukemia. Br J Haematol. 1993;83:412.
9. Nizet Y, Daele V, Lewalle P, et al. Long-term follow-up of residual disease in acute lymphoblastic leukemia patients in complete remission using clongenic IgH probes and the polymerase chain reaction. Blood 1993;82:1618.
10. Hagenbeek A. Minimal residual disease in leukemia: State of the art 1991. Leukemia. 1992;6(Suppl 2):12.