Change in platelet GTP-binding protein in drug-free depressed patients

Human Psychopharmacology

Volumn 11, Issue 2, 1996, Pages 115-121

  Karege, Félicien ^a   Bovier, Philippe ^a   Stepanian, Renata ^a   Gaillard, Jean Michel ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

alpha2 adrenoceptor; depression; GTP S; GTP binding protein; platelet

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SUBUNIT;

ADULT; ARTICLE; CLINICAL ARTICLE; DEPRESSION; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; THROMBOCYTE;

EID: 0029991294     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1077(199603)11:2<115::AID-HUP762>3.0.CO;2-B     Document Type: Article

References (33)

1. Avissar, S. and Schreiber, G. (1992). The involvement of guanine nucleotide binding proteins in the pathogenesis and treatment of affective disorders. Biological Psychiatry, 31, 435-459.
2. Birnbaumer, L., Abramowitz, J. and Brown, A. M. (1990). Receptor-effector coupling by G proteins. Biochimica and Biophysica Acta, 1031, 163-224.
3. Birnbaumer, L. (1992). Receptor-to-effector signaling through G proteins: Roles for βγ dimers as well as α subunits. Cell, 71, 1069-1072.
4. Bobon, D. P. (1981). Le Système AMDP. Manuel de Documentation et de Quantification de la Psychopathologie, 2nd edn. Mardaga, Brussels.
5. Bradford, M. (1976). A rapid and sensitive method for the quantitation of micrograms quantities of protein utilizing the principle of protein dye binding. Analytical Biochemistry, 72, 248-254.
6. 2-adrenoceptor levels on platelet of patients with major depressive disorders. Psychiatry Research, 18, 312-331.
7. Escriba, P. V., Sastre, M. and Garcia-Sevilla, J. A. (1994). Increased density of guanine nucleotide-binding (G) proteins in the postmortem brain of heroin addicts. Archives of General Psychiatry, 51, 494-501.
8. 2-adrenoceptors in major affective disorder. Archives of General Psychiatry, 43, 51-57.
9. Gierschik, P., Moghtader, R., Straub, C., Dieterich, K. and Jakobs, K. H. (1991). Signal amplification in HL-60 granulocytes. Evidence that chemotactic peptide receptor catalytically activates guanine-nucleotide-binding regulatory proteins in native plasma membranes. European Journal of Biochemistry, 197, 725-732.
10. Gilman, A. G. (1987). G proteins: Transduction of receptor-generated signals. Annual Review of Biochemistry, 56, 615-649.
11. Hepler, J. R., Kozasa, T., Smrcka, A. V., Simon, M. I., Rhee, S. G., Sternweis, P. C. and Gilman, A. G. (1993). Purification from Sf9 cells and characterization of recombinant Gqα and G11α. Activation of purified phospholipase C isozymes by Gα subunit. Journal of Biological Chemistry, 268, 14367-14375.
12. Hudson, C. J., Young, L. T., Li, P. P. and Warsh, J. J. (1993). CNS transmembrane signal transduction abnormalities in the pathophysiology and pharmacotherapy of affective disorders and schizophrenia. Synapse, 13, 278-293.
13. Kaneko, M., Kanno, T., Honda, K., Mashiko, H., Oosuga, N., Watanabe, K. and Kumashiro, H. (1992). Platelet α2-adrenergic receptor binding and plasma-free MHPG in depressed patients before and after treatment with mianserin. Neuropsychobiology, 25, 14-19.
14. Karege, F., Bovier, Ph., Gaillard, J.-M. and Tissot, R. (1991). Regulation of platelet α2-adrenoceptors in depression. Biological Psychiatry, 29, 333S-701S.
15. Karege, F., Bovier, P., Widmer, J., Gaillard, J.-M. and Tissot, R. (1992). Decrease in epinephrine-induced attenuation of platelet adenylate cyclase activity in depressed patients: relation with plasma electrolytes. Neuropsychobiology, 26, 129-135.
16. Karege, F., Bovier, P., Rudolph, W. and Gaillard, J.-M. (1996). Platelet phosphoinositide signaling system. An overstimulated pathway. Biological Psychiatry, 39, in press.
17. Lachman, H. M. and Papolos, D. F. (1989). Abnormal signal transduction: a hypothetical model for bipolar affective disorder. Life Sciences, 45, 1413-1426.
18. Manji, H. K. (1992). G Proteins: implications for psychiatry. American Journal of Psychiatry, 149, 746-759.
19. Manji, H. K., Chen, G., Shimon, H., Hsiao, J. K., Potter, W. Z. and Belmaker, R. H. (1995). Guanine nucleotide-binding proteins in bipolar disorder. Effects of long-term treatment. Archives of General Psychiatry, 52, 135-144.
20. Mooney, J. J., Schatzberg, A. F., Cole, J. O., Kizuka, P. P., Salomon, M., Lerbinger, J., Pappalardo, K. M., Gerson, B. and Schildkraut, J. J. (1988). Rapid antidepressant response to alprazolam in depressed patients with high catecholamine output and heterologous desensitization of platelet adenylate cyclase. Biological Psychiatry, 23, 543-559.
21. 2-adrenergic receptor-mediated phosphoinositide responses in endogenous depression. Life Sciences, 48, 741-748.
22. Odagaki, Y., Koyama, T. and Yamashita, I. (1994). Platelet pertussis toxin-sensitive G proteins in affective disorders. Journal of Affective Disorders, 31, 173-177.
23. Ozawa, H., Gsell, W., Frolich, L., Zochling, R., Pantucek, F., Beckmann, H. and Riederder, P. (1993): Imbalance of the Gs and Gi/o function in postmortem brain of depressed patients. Journal of Neural Transmission, 94, 63-69.
24. 3H-para-amino-clonidine binding to platelet purified plasma membranes from depressed patients. Neuropsychopharmacology, 3, 201-210.
25. Sánchez-Blanque, A. (1989). In European Handbook of Psychiatry and Mental Health. Seva, A. (ed). University Press of Zaragoza, Anthropos, pp. 639-647.
26. Schreiber, G., Avissar, S., Danon, A. and Belmaker, R. H. (1991). Hyperfunctional G proteins in mononuclear leukocytes of patients with mania. Biological Psychiatry, 29, 273-280.
27. Siever, L. J., Kafka, M. S., Targum, S. and Lake, C. R. (1984). Platelet alpha-adrenergic binding and biochemical responsiveness in depressed patients and controls. Psychiatry Research, 11, 287-302.
28. Spiegel, A. M. (1992). Heterotrimeric GTP-binding proteins: an expanding family of signal transducers. Medical Research Review, 12, 55-71.
29. Spiegel, A. M., Weinstein, L. S. and Shenker, A. (1993). Abnormalities in G proteins-coupled signal transduction pathways in human disease. Journal of Clinical Investigation, 92, 119-1125.
30. 3H-imipramine binding and plasma cortisol level in depression. Biological Psychiatry, 26, 52-60.
31. Wachtel, H. (1989). Dysbalance of neuronal second messenger function in the aetiology of affective disorders: a pathophysiological concept hypothesizing defects beyond first messenger receptors. Journal of Neural Transmission, 7, 21-29.
32. Young, L. T., Li, P. P., Kish, S. J., Siu, K. P. and Warsh, J. J. (1991). Postmortem cerebral cortex Gsα-subunit levels are elevated in bipolar affective disorder. Brain Research, 553, 323-326.
33. Young, L. T., Li, P. P., Kamble, A. R., Siu, K. P. and Warsh, J. J. (1994). Mononuclear leukocyte levels of G proteins in depressed patients with bipolar disorder or major depressive disorder. American Journal of Psychiatry, 151, 594-596.