The toxin-coregulated pilus is a colonization factor and protective antigen of Vibrio cholerae El Tor

Microbial Pathogenesis

Volumn 20, Issue 3, 1996, Pages 141-153

  Voss, Elena ^a   Manning, Paul A ^a   Attridge, Stephen R ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Colonization factor; Protective antigen; Toxin coregulated pilus; Vibrio cholerae

Indexed keywords

ANTISERUM; BACTERIAL ANTIGEN; BACTERIAL TOXIN; CHOLERA VACCINE;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM PILUS; CHOLERA; CONTROLLED STUDY; IMMUNOBLOTTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SERUM; VIBRIO CHOLERAE;

ANIMALIA; BACTERIA (MICROORGANISMS); VIBRIO CHOLERAE; VIBRIO CHOLERAE O1 BIOVAR ELTOR;

EID: 0029991175     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.1996.0013     Document Type: Article

References (25)

1. Taylor RK, Miller VL, Furlong DB, Mekalanos JJ. The use of phoA gene fusions to identify a pilus colonisation factor co-ordinately regulated with cholera toxin. Proc Natl Acad Sci USA 1987; 84: 2833-7.
2. Herring ton DA, Hall RH, Losonsky G, Mekalanos JJ, Taylor RK, Levine MM. Toxin, toxin-coregulated pili and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med 1988; 168: 1487-92.
3. Sharma D, Thomas CJ, Hall RH, Levine MM, Attridge SR. Significance of toxin-coregulated pill as protective antigens of Vibrio cholerae in the infant mouse model. Vaccine 1989; 7: 451-6.
4. Sun D, Mekalanos JJ, Taylor RK. Antibodies directed against the toxin-coregulated pilus from Vibrio cholerae provide protection in the infant mouse experimental cholera model. J Infect Dis 1990; 161: 1231-6.
5. Sun D, Tillman DM, Marion TN, Taylor RK. Production and characterisation of monoclonal antibodies to the toxin-coregulated pilus (TCP) of Vibrio cholerae that protect against experimental cholera in infant mice. Serodiag Immunother Infect Dis 1990; 4: 73-81.
6. Hall RH, Losonsky G, Silviera APD et al. Immunogenicity of Vibrio cholerae O1 toxin-coregulated pili in experimental and clinical cholera. Infect Immun 1991; 59: 2508-12.
7. Jonson G, Holmgren J, Svennerholm AM. Epitope differences in toxin-coregulated pili produced by classical and El Tor Vibrio cholerae O1. Microb Pathog 1991; 11: 179-88.
8. Voss E, Attridge SR. In vitro production of toxin-coregulated pili by Vibrio cholerae El Tor. Microb Pathog 1993; 15: 255-68.
9. Attridge SR, Voss E, Manning PA. The role of toxin-coregulated pili in the pathogenesis of Vibrio cholerae O1 El Tor. Microb Pathog 1993; 15: 421-31.
10. Rhine J, Taylor RK. TcpA pilin sequences and colonisation requirements for O1 and O139 Vibrio cholerae. Mol Microbiol 1994; 13: 1013-20.
11. Nair BG, Ramamurthy SK, Mukhopadhyay K et al. Spread of Vibrio cholerae O139 Bengal in India. J infect Dis 1994; 169: 1029-34.
12. Johnson JA, Salles CA, Panigrahi P et al. Vibrio cholerae O139 synonym Bengal is closely related to Vibrio cholerae El Tor but has important differences. Infect Immun 1994; 62: 2108-10.
13. Iredell J, Manning PA. Biotype-specific tcpA genes in Vibrio cholerae. FEMS Microbiol Lett 1994; 121: 47-54.
14. Jones DH, Howard BH. A rapid method for recombination and site-specific mutagenesis by placing homologous ends on DNA using polymerase chain reaction. Biotech 1991; 10: 62-6.
15. Kaniga K, Delor I, Cornelis GR. A wide-host-range suicide vector for improving reverse genetics in Gram-negative bacteria: inactivation of the blaA gene of Yersinia enterocolitica. Gene 1993; 109: 137-41.
16. Williams SG, Attridge SR, Manning PA. The transcriptional activator HlyU of Vibrio cholerae: nucleotide sequence and role in gene expression. Mol Microbiol 1993; 9: 751-60.
17. Donnenberg MS, Kaper JB. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect Immun 1991; 59: 4310-7.
18. Blomfield IC, Vaughn V, Fest RF, Einstein BI. Allelic exchange in Escherichia coli using the Bacillus subtilis sacB gene and temperature sensitive pSC101 replicon. Mol Microbiol 1991; 5: 1447-57.
19. Sharma D, Stroeher UH, Thomas CJ, Manning PA, Attridge SR. The toxin-coregulated pilus (TCP) of Vibrio cholerae: molecular cloning of genes involved in pilus biosynthesis and evaluation of TCP as a protective antigen in the infant mouse model. Microb Pathog 1989; 7: 437-48.
20. Brown RC, Taylor RK. Organization of tcp, acf and toxT genes within a ToxT-dependent operon. Mol Microbiol 1995; 16: 425-39.
21. Shaw CE, Peterson KM, Mekalanos JJ, Taylor RK. Genetic studies of Vibrio cholerae TCP pilus biogenesis. In: Sack RB, Zinnaka Y, eds. Advances in Research on Cholera and Related Diarrheas. Tokyo: KTK Scientific Publications, 1990: 51-8.
22. Osek J, Jonson G, Svennerholm A-M, Holmgren J. Role of antibodies against biotype-specific Vibrio cholerae pili in protection against experimental classical and El Tor cholera. Infect Immun 1994; 62: 2901-7.
23. Vieira J, Messing J. The pUC plasmids, a M 13mp-7 derived system for insertion mutagenesis and sequencing with synthetic universal primers. Gene 1982; 19: 259-68.
24. Attridge SR, Rowley D. Prophylactic significance of the non-lipopolysaccharide antigens of Vibrio cholerae. J Infect Dis 1983; 148: 931-9.
25. Attridge SR, Rowley D. The role of the flagellum in the adherence of Vibrio cholerae. J Infect Dis 1983; 147: 864-72.